Hematopathology Resident / Fellow Manual - Department of ...

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Chronic Myeloproliferative Neoplasms Chronic Myelogenous Leukemia Myelodysplastic/Myeloproliferative Disease Juvenile Myelomonocytic Leukemia Myelodysplastic Syndromes Childhood Myelodysplastic Syndromes Refractory cytopenia <strong>of</strong> childhood Mature Lymphoid Neoplasms Burkitt Lymphoma Diffuse Large B-cell Lymphoma Anaplastic Large Cell Lymphoma, ALK+ Pediatric Nodal Marginal Zone Lymphoma Pediatric Follicular Lymphoma Systemic EBV+ T-cell LPD <strong>of</strong> Childhood Hydroa Vacciniforme-like Lymphoma Nodular Lymphocyte Predominant Hodgkin Lymphoma Classical Hodgkin Lymphoma Histiocytic Neoplasms Langerhans cell histiocytosis Mast Cell Disease Metastatic Tumors Neuroblastoma Rhabdomyosarcoma Ewing sarcoma NON-NEOPLASTIC DISORDERS Congenital Disorders/Syndromes with Prominent Hematologic Abnormalities (Hereditary bone marrow failure) Fanconi Anemia
Diamond Blackfan Syndrome Congenital Dyserythropoietic Anemia Congenital Sideroblastic Anemia Pearson Syndrome Severe Congenital Neutropenia/Kostmann’s Syndrome Cyclic Neutropenia Shwachman-Diamond Syndrome Dyskeratosis Congenita Reticular Dysgenesis May-Hegglin Anomaly Bernard-Soulier Syndrome Wiskott-Aldrich Syndrome Congenital Amegakaryocytic Thrombocytopenia
Page 1 and 2: DIVISION OF HEMATOPATHOLOGY HEMATOP
Page 3 and 4: TABLE OF CONTENTS (cont.) LYMPH NOD
Page 5 and 6: HEMATOPATHOLOGY FACULTY Long Range
Page 7 and 8: General Outline for Hematopathology
Page 9 and 10: General/Special Hematology Laborato
Page 11 and 12: Hematopathology Progressive Goals a
Page 13 and 14: Competency Core Rotation - 1st to 3
Page 19 and 20: CONFERENCE SCHEDULE AND RESPONSIBIL
Page 21 and 22: RESIDENT AND FELLOW CONFERENCE RESP
Page 23 and 24: y the faculty member. Case presenta
Page 25 and 26: Additional information regarding Sh
Page 27 and 28: Pediatric Hematopathology and Gener
Page 29 and 30: General/Special Hematology Experien
Page 31 and 32: General Hematology Laboratory (ATL)
Page 33 and 34: QC/QA Procedures, graphing Running
Page 35 and 36: • Test of RBC function Know how t
Page 37 and 38: HEMOGLOBIN ANALYSIS CASE LOG ACCESS
Page 39 and 40: PB AND FLUID REVIEW LOG ACCESSION N
Page 41: Pediatric Hematopathology Checklist
Page 45 and 46: Drugs/toxins Infection-associated T
Page 47 and 48: PRESENTED THE FOLLOWING PEDIATRIC B
Page 49 and 50: UPMC PRESBYTERIAN SHADYSIDE Automat
Page 51 and 52: Clinical Experience in Hematology
Page 53 and 54: Performance of Bone Marrow Aspirati
Page 55 and 56: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. HEMA
Page 57 and 58: Flow Cytometry Laboratory Experienc
Page 59 and 60: Chronic leukemia Hairy Cell Leukemi
Page 61 and 62: MDS / Cytopenia Panel (BM and PB) F
Page 63 and 64: Mini (T) Acute Lymphoblastic Leukem
Page 65 and 66: Validated Extra Tubes: FITC PE PerC
Page 67 and 68: FITC PE PerCP PerCP- CY5.5 X PE- Cy
Page 69 and 70: of the results, or the morphologic
Page 71 and 72: TEST SPECIFICATIONS: CLINICAL FLOW
Page 73 and 74: ICD9 Codes for Flow A list of ICD9
Page 75 and 76: Adult Bone Marrow Experience (~4 we
Page 77 and 78: 7. In consultation with staff patho
Page 79 and 80: IV. Quality assurance is very impor
Page 81 and 82: APPENDIX C LOCATION OF BONE MARROW
Page 83 and 84: ADULT BONE MARROW SERVICE REQUEST F
Page 85 and 86: Promyel ___________% __________(ABS
Page 87 and 88: ADULT BONE MARROW WORKSHEET INSIDE
Page 89 and 90: Plasma Cells _____________% 2.0 ( 0
Page 91 and 92: DAY 14 BONE MARROW WORKSHEET Techno
Page 93 and 94:
Blasts _________% __________(ABS) P
Page 95 and 96:
Case number:_______________________
Page 97 and 98:
Surgical Pathology Cancer Case Summ
Page 99 and 100:
___ Acute myelomonocytic leukemia _
Page 101 and 102:
___ Classical Hodgkin lymphoma type
Page 103 and 104:
Explanatory Notes A. Specimen Compl
Page 105 and 106:
Hemoglobin less than 8.5 g/dL (85 g
Page 107 and 108:
6. Lymphoid neoplasms. In: Edge SB,
Page 109 and 110:
TEST SPECIFICATIONS: BONE MARROW LA
Page 111 and 112:
Summary of Test Specifications for
Page 113 and 114:
AFTER-HOURS PROCEDURES (CHILDREN’
Page 115 and 116:
6. Cytogenetics: Monday through Th
Page 117 and 118:
Lymph Node Pathology Experience (~4
Page 119 and 120:
(Warning: Formalin is a suspected c
Page 121 and 122:
6.8 Cut a small paper thin slice, p
Page 123 and 124:
6.13.2 Fresh tissue for special lab
Page 125 and 126:
How to handle very small specimens
Page 127 and 128:
Surgical Pathology Manual: Spleen P
Page 129 and 130:
Policy for solid tissue specimens s
Page 131 and 132:
Fresh Case Lymph Nodes and Other So
Page 133 and 134:
RULES FOR HISTOLOGY All exceptions
Page 135 and 136:
All recuts, special stains, and imm
Page 137 and 138:
EXAMPLE: Consult material descripti
Page 139 and 140:
For multiple parts with one or more
Page 141 and 142:
CLINICAL HISTORY In the clinic
Page 143 and 144:
6.2.3 Determine if any slides that
Page 145 and 146:
J chain AJ BCL2 ABCL2 BCL2 E17 ABCL
Page 147 and 148:
MOLECULAR DNA/RNA (Already Stored)
Page 149 and 150:
Lymph Node Rotation Checklist Note:
Page 151 and 152:
Diagnosis / Finding Observed Actual
Page 153 and 154:
Diagnosis / Finding Observed Actual
Page 155 and 156:
Angiosarcomas Nonvascular sarcom
Page 157 and 158:
UTILIZED THE FOLLOWING LYMPH NODE R
Page 159 and 160:
Surgical Pathology Cancer Case Summ
Page 161 and 162:
Lymphomatoid papulosis Primary cuta
Page 163 and 164:
Explanatory Notes A. Specimen Any n
Page 165 and 166:
### The number of lymph node region
Page 167 and 168:
Hairy Cell Leukemia: sIG+ (IGM, IGD
Page 169 and 170:
t(8;22)(q24;q11); rearranged MYC ge
Page 171 and 172:
F. Clinical Prognostic Factors and
Page 173 and 174:
33. Osterman B, Cavallin-Stahl E, H
Page 175 and 176:
where the differential diagnosis in
Page 177 and 178:
Immunophenotypes 1,4-8 The followin
Page 179 and 180:
Immunohistochemistry
Page 181 and 182:
2. If you are ordering the panel us
Page 183 and 184:
CD57 (Leu 7) ALEU7 NK-cells, Neural
Page 185 and 186:
Complete Immunohistochemical Stain
Page 187 and 188:
CD5 CD5 CD56 CD56 CD57 CD57 CD61 CD
Page 189 and 190:
HHV8 HMB45 Melanoma HPV Papilloma V
Page 191 and 192:
P501S P504S P53 Tumor Suppressor Pr
Page 193 and 194:
CODES FOR DOUBLE LABELING ICKDE AE1
Page 195 and 196:
PHS/B:______________________ PARAFF
Page 197:
Molecular Diagnostic and Cytogeneti
Page 200:
PITTSBURGH CYTOGENETICS LABORATORY
Page 204 and 205:
FISH panels for Hematologic Maligna
Page 206 and 207:
CML Strategy ES probe 1. BCR/ABL ES
Page 208 and 209:
COPATH Related Instructions for Dic
Page 210 and 211:
Division of Hematopathology Dictati
Page 212 and 213:
Wording for Provisional Reports on
Page 214 and 215:
Bone Marrow/Peripheral Blood Hemato
Page 216 and 217:
Page 218 and 219:
Page 220 and 221:
Page 222 and 223:
Non-Hodgkins Lymphoma Biopsy/Resect
Page 224 and 225:
Page 226 and 227:
Page 228 and 229:
Hodgkin Lymphoma Biopsy/Staging Syn
Page 230 and 231:
Web-Based Resources
Page 232:
Educational Site 1. http://www.cyto
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