168. Marathe, Punit H., Sandefer, Erik P., Kollia, Georgia E., Greene, Douglas S., Barbhaiya, Rashmi H., Lipper, Robert A., Page, Richard C., Doll, Walter J., Ryo, U.Y. and <strong>Digenis</strong>, <strong>George</strong> A., "In Vivo Evaluation <strong>of</strong> the Absorption and Gastrointestinal Transit <strong>of</strong> Avitriptan in Fed and Fasted Subjects Using Gamma Scintigraphy", J. <strong>of</strong> <strong>Ph</strong>armacokinetics and Biopharmaceutics, 26(1), 1-20, 1998. 169. Parr, Alan F., Sandefer, Erik P., Wissel, Paul, McCartney, Mike, McClain, Craig, Ryo, U.Y., and <strong>Digenis</strong>, <strong>George</strong> A., "Evaluation <strong>of</strong> the Feasibility and Use <strong>of</strong> a Prototype Remote Drug Delivery Capsule (RDDC) for Non-Invasive Regional Drug Absorption Studies in the GI Tract <strong>of</strong> Man and Beagle Dog", <strong>Ph</strong>armaceutical Research, 16(2), 266- 271, 1999. 170. <strong>Digenis</strong>, G.A., Nosek, D., Mohammadi, F., Darwazeh, N.B., Anwar, H.S., and Zavos, P.M., "Novel Vaginal Controlled-Delivery Systems Incorporating Coprecipitates <strong>of</strong> Nonoxynol-9", <strong>Ph</strong>arm. Dev. and Tech., 4(3) 421-430, 1999. 171. Li-Pan, Zhanyi Sky, Joshi, Hemant V., and <strong>Digenis</strong>, <strong>George</strong> A., "Synthesis and Mechanism <strong>of</strong> Action <strong>of</strong> Novel Thiocarbamate Inhibitors <strong>of</strong> Human Leukocyte Elastase", J. Enzyme Inhibition, 15, 63-77,1999. 172. <strong>Digenis</strong>, <strong>George</strong> A., Sandefer, Erik P., Page, Richard C., and Doll, W.J., "Recent Advances in Formulation Development with Gamma Scintigraphy", <strong>Ph</strong>arm. Tech. Japan, Part I, 15(8), 1125-1133, (1999). 173. <strong>Digenis</strong>, <strong>George</strong> A., Sandefer, Erik P., Page, Richard C., and Doll, W.J., "Recent Advances in Formulation Development with Gamma Scintigraphy", <strong>Ph</strong>arm. Tech. Japan, Part II, 15(9), 1289-1293, (1999). 174. <strong>Digenis</strong>, <strong>George</strong> A., Sandefer, Erik P., Page, Richard C., and Doll, W.J., "Recent Advances in Formulation Development with Gamma Scintigraphy", <strong>Ph</strong>arm. Tech. Japan, Part III, 15(10), 1453-1457, (1999). 175. <strong>Digenis</strong>, <strong>George</strong> A., Sandefer, Erik P., Page, Richard C., and Doll, W.J., "Recent Advances in Formulation Development with Gamma Scintigraphy", <strong>Ph</strong>arm. Tech. Japan, Part IV, 15(11), 1633-1638, (1999). 176. <strong>Digenis</strong>, G.A., Sandefer, E.P., Page, R.C., Doll, W.J., Gold, T.B., and Darwazeh, N.B., “Bioequivalence Study <strong>of</strong> Stressed and Nonstressed Hard Gelatin Capsules Using Amoxicillin as a Drug Marker and Gamma Scintigraphy to Confirm Time and GI Location <strong>of</strong> In Vivo Capsule Rupture”, <strong>Ph</strong>arm. Res., 17, 5:572-582, 2000. 177. Rodis, Nikolaos P. and <strong>Digenis</strong>, <strong>George</strong> A., “Synthesis and In-Vitro Evaluation <strong>of</strong> Novel Low Molecular Weight Thiocarbamates as Inhibitors <strong>of</strong> Human Leukocyte Elastase”, J. <strong>of</strong> Enzyme Inhibition, 16:2, 95-105, 2001. 178. Fowler, <strong>Ph</strong>illip T., Matsumoto, Kazuya, Page, Richard C., and <strong>Digenis</strong>, <strong>George</strong> A., “Synthesis <strong>of</strong> Novel Iodinated Derivatives <strong>of</strong> Nonoxynol-9 and Their Bioavailability in Rats”, Nucl. Med. Biol, 29(7):771-775, 2002. 179. Qasem, J.G., Bummer, Paul M., and <strong>Digenis</strong>, <strong>George</strong> A., “Kinetics <strong>of</strong> Paclitaxel 2-Nmethylpyridinium Mesylate Decomposition”, <strong>Ph</strong>armSciTech, 4(2), 2003. 180. Fowler, <strong>Ph</strong>illip T., Doncel, Gustavo F., Bummer, Paul M., and <strong>Digenis</strong>, <strong>George</strong> A., “Complexation <strong>of</strong> Nonoxynol-9 with Polyvinylpyrroliodone to Decrease Vaginal Irritation Potential”. <strong>Ph</strong>armSciTech, 4(3), 2003. 181. Hussain, M.A., Chang, R-K, C., Sandefer, E., Page, R.C., and <strong>Digenis</strong>, G.A., “Evaluation <strong>of</strong> the in vivo disintegration <strong>of</strong> solid dosage forms <strong>of</strong> a bile acid sequestrant in dogs using γ-scintigraphy and correlation to in vitro disintegration”. <strong>Ph</strong>arm. Res. 20 (3), 460- 464, 2003. 29
182. Gao, Z.J., Hussain, M.D., Motheram, R., Gray, D.A., Denedek, I.H., Fiske, W.D., Doll, W.J., Sandefer, E., Page, R.C., and <strong>Digenis</strong> G.A., “Investigation <strong>of</strong> human pharmacoscientigraphic behavior <strong>of</strong> two tablets and a capsule formulation <strong>of</strong> a high dose, poorly water soluable/high permeable drug (Efaverenz)”, J. <strong>Ph</strong>arm. Sci., (in press). 183. Al-Ghananeem, A.M., Sandefer, E.P., Doll, W., Page, R.C., Chang, Y., and <strong>Digenis</strong>, G.A., “Gamma Scintigraphy for Testing Bioequivalence: A Case Study on Two Cromolyn Sodium Nasal Spray Preparations”, Inter. J. <strong>of</strong> <strong>Ph</strong>armaceutics, 2008 (in press). 30 Books and Chapters 1. <strong>Digenis</strong>, G.A. and Swintosky, J.V., "Drug Latentiation," in Handbook <strong>of</strong> Experimental <strong>Ph</strong>armacology (Concepts in Biochemical <strong>Ph</strong>armacology), Vol. 28/3, J.R. Gillette and B.B. Brodie, editors, Springer-Verlag Berlin, New York (1975). 2. <strong>Digenis</strong>, G.A., "Toxicology Studies: Utilization <strong>of</strong> Short-lived Radionuclides in the Assessment <strong>of</strong> the Safety and Disposition <strong>of</strong> Novel Products," in Research Frontiers in Fertility Regulation, G.I. Zatuchni, Mirian H. Labbok, John J. Sciarra, eds., pp. 23-31, Harper and Row Publishers, New York (1980). 3. <strong>Digenis</strong>, G.A., "The Utilization <strong>of</strong> Short-lived Radionuclides in the Assessment <strong>of</strong> Formulation and In Vivo Disposition <strong>of</strong> Drugs," Radionuclide Imaging in Drug Research, Edited by C.G. Wilson, J.G. Hardy, with S.S. Davis and M. Frier (Croom Helm, London, 1982) pp. 103-143. 4. <strong>Digenis</strong>, G.A. and Ansell, J., editors, "Proceedings <strong>of</strong> the First International Symposium on Povidone," Lexington, <strong>Kentucky</strong>, <strong>University</strong> <strong>of</strong> <strong>Kentucky</strong>, 1983. 5. Mlodozeniec, A.R., Caldwell, L., Jay, Michael, Beihn, R.M., and <strong>Digenis</strong>, <strong>George</strong> A.; Noninvasive Monitoring <strong>of</strong> the In Vivo Release Characteristics <strong>of</strong> Rectal Drug Delivery Devices, Recent Advances in Drug Delivery Systems, Edited by James M. Anderson and Sung Wan Kim, Plenum Publishing Corporation, (1984). 6. <strong>Digenis</strong>, <strong>George</strong> A., Jay, Michael, Beihn, Robert M., Tice, Thomas R., Beck, Lee R., External Scintigraphy in the Study <strong>of</strong> Long-Acting Contraceptive Delivery Systems. Long-Acting Contraceptive Delivery Systems, Edited by G. I. Zatuchni, Alfredo Goldsmith, J.D. Shelton and John J. Sciarra, Harper and Row, (1984). 7. <strong>Digenis</strong>, G.A. and Agha, B.J., editors, "Proceedings <strong>of</strong> the Second International Symposium on Povidone" <strong>University</strong> <strong>of</strong> <strong>Kentucky</strong>, Lexington, <strong>Kentucky</strong>. (1987). 8. <strong>Digenis</strong>, G.A., Parr, A., Jay, M., "Neutron Activation Methods for Evaluation <strong>of</strong> <strong>Ph</strong>armaceutical Dosage Forms", in Drug Delivery to the Gastrointestinal Tract, edits. J.G. Hardy, S.S. Davis and C.G. Wilson, Ellis Horwood Press, Chichester, England 1989, pp 111-119. 9. <strong>Digenis</strong>, <strong>George</strong> A. and Sandefer, Erik, "Gamma Scintigraphy and Neutron Activation Techniques in the In Vivo Assessment <strong>of</strong> Orally Administered Dosage Forms", in Critical Reviews in Therapeutic Drug Carrier Systems, 7, 309-346 (1991) CRC Press, Inc. 10. <strong>Digenis</strong>, <strong>George</strong> A., "In Vivo Behavior <strong>of</strong> Multiparticulate Versus Single-Unit Dose Formulations", in Multiparticulate Oral Drug Delivery, Edited by Isaac Ghebre-Sellassie, Marcel Dekker, Inc., 1994, pp 333-355. 11. <strong>Digenis</strong>, <strong>George</strong> A.and Erik P. Sandefer, "Acceleration <strong>of</strong> <strong>Ph</strong>armaceutical Research and Development with Application <strong>of</strong> Gamnma Scintigraphy", in European <strong>Ph</strong>armaceutical Contractor, pp 22-32, 1999.
- Page 1 and 2: 1 Curriculum Vitae George A. Digeni
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