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George A. Digenis, Ph.D. - University of Kentucky - College of ...

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National Institutes <strong>of</strong> Health, "Preparation and Disposition <strong>of</strong> 11 C- D- and L-Amino Acids,"<br />

$51,137 (3rd year renewal).<br />

Program for Applied Research Fertility Regulation, "Development <strong>of</strong> Methodology for<br />

Following Microcapsule Transcervical Transport in Baboons Utilizing External Scintigraphy,"<br />

$10,966.<br />

Rowell Laboratories, "Cortenema Imaging Studies," $31,232 (lst year) Co- investigators: T.<br />

Foster and M. Jay (1983).<br />

INTERx, Merck, Sharp & Dohme Research Labs, "External Scintigraphy to Study Disposition<br />

<strong>of</strong> Rectal Dosage Form Matrix In Vivo," $20,000 (2nd year). Co-investigator: M. Jay.<br />

Ortho <strong>Ph</strong>armaceutical Corporation, "A Study on the Disposition <strong>of</strong> Vaginally Administered<br />

Nonoxynol-9 in Barren and Pregnant Rats," $10,000 (1983).<br />

"Ciba-Geigy Corporation, "External Scintigraphic Studies <strong>of</strong> Labeled Slow-K Tablets," $8,000<br />

(1983).<br />

"Polyamines and Suicide Inhibitors in Tumor Imaging," $178,000 (direct costs) National<br />

Cancer Institute (1984-1987).<br />

"Tobacco and Health Research Institute, "Design and Synthesis <strong>of</strong> Specific Human Leukocyte<br />

Elastase Inhibitors", $55,139. (84-85).<br />

"GI Transit Times <strong>of</strong> Two Radiolabelled Placebo Formulations", $7,000, (1984).<br />

"Radionuclide Studies", $12,000, (G.A. <strong>Digenis</strong> and M.Jay), INTERx, Merck and Company<br />

(1984).<br />

"Neutron Activation Study", $15,000 (G.A. <strong>Digenis</strong> and M. Jay) $15,000, INTERx, Merck and<br />

Company (84-85).<br />

"Correlation <strong>of</strong> In Vitro and In Vivo Dissolution to Bioavailability by External Scintigraphy<br />

and Perturbed Angular Correlation", $45,000, (84-86).<br />

"Comparative Serum Concentratins <strong>of</strong> Theophylline in the Dog after Oral Administration <strong>of</strong><br />

111In-labelled Searle Theophylline CR-24 Preparation With and Without Food", $12,000,<br />

Searle Research and Developement, Division <strong>of</strong> G.D. Searle and Company (1985).<br />

"Radionuclide Studies" Interx, Merck and Company (continued), $20,025 (with Dr. M. Jay),<br />

(85-86).<br />

"Kinetics and Mechanism <strong>of</strong> Degradation <strong>of</strong> Aspartame", $25,000, Searle Research and<br />

Development (Searle Food Resources) (with Dr. A. Hussain) (1986).<br />

"Correlation <strong>of</strong> the GI Behavior <strong>of</strong> Erythromycin Beads to the Bioavailability <strong>of</strong> the Drugs",<br />

pending, (b) "Disposition <strong>of</strong> Calcium Carbonate After Oral Administration in Man", Warner-<br />

Lambert Co. $25,000 (1986)<br />

"(a)"Synthesis <strong>of</strong> C-Alprazolam", pending; (b)"Synthesis and Preliminary Disposition studies<br />

with 19 F-Flurbipr<strong>of</strong>en", The Upjohn Company, $110,000 (1986).<br />

"Assessment <strong>of</strong> a Bioadhesive Coating on the GI Transit Time <strong>of</strong> Pellets in Humans", $75,000<br />

(1986), "Purchase <strong>of</strong> Gamma Camera", $25,000, Eli Lilly, Company (1986).<br />

"Novel Elastase Inhibitors: Mechanism and In Vivo Studies, $331,988 (3 years) National<br />

Institute <strong>of</strong> Health, Pending (1986).<br />

"Clinical Evaluation <strong>of</strong> Polymeric Dosage Forms <strong>of</strong> 5ASA", Eastman Kodak Company,<br />

$70,000 (with Dr. T. Foster) December, 1986 - June, 1988.<br />

"Studies on Polymerbound Peptidyl Carbamates", $43,500, Tobacco and Health Research<br />

Institute, July, 1987 - June 1988.<br />

47

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