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visual method of diagnosis can detect dentine caries with<br />

a sensitivity in excess of 0.6 and a specificity in excess of<br />

0.8 in a sample of borderline lesions.<br />

In the Downer histology the enamel-dentine junction<br />

is taken as a diagnostic threshold to calculate diagnostic<br />

accuracy at the D3 level (code 2–3), whereas in the ERK<br />

histological system the enamel-dentine junction is not<br />

used and the histological threshold 2–3 corresponds to<br />

deeper dentine lesions (a threshold between outer third<br />

of dentine and middle third of dentine). Despite this, similar<br />

levels of sensitivity and specificity were obtained<br />

when the same ICDAS-II cut-off 2–3 was used. Using<br />

these ICDAS-II cut-offs and ERK histological threshold<br />

allowed comparison with previous work where higher<br />

sensitivity (0.92–0.97) and specificity (0.85–0.93) values<br />

were obtained [Ekstrand et al., 1997]. In the present study,<br />

when a higher ICDAS-II cut-off 3–4 was used, specificity<br />

values increased to a mean of 0.90 at the expense of sensitivity,<br />

which fell to a mean of 0.60. However, the level of<br />

overall accuracy (sensitivity plus specificity) was of the<br />

same order of magnitude as when ICDAS-II cut-off 2–3<br />

was used.<br />

A review of studies that included the validation of diagnostic<br />

techniques against a histological gold standard<br />

[Ie and Verdonschot, 1994] showed that visual inspection<br />

performed comparatively poorly for occlusal caries diagnosis<br />

compared to electrical resistance measurements<br />

and fibre-optic transillumination. In addition to this, another<br />

systematic review of the literature has shown that<br />

for visual examination specificity is high but sensitivity<br />

is low [Bader et al., 2001]. In these two reviews meta-analyses<br />

have either not been carried out or the results should<br />

be regarded with caution because of the heterogeneity of<br />

the studies included. However, it would appear that in<br />

general, visual examination has been regarded as poor for<br />

caries detection. In contrast, this study has shown that by<br />

meticulously examining clean dry teeth sensitivity of a<br />

visual examination can be improved after a short training<br />

period.<br />

In summary, after a relatively short training period 3<br />

examiners were able to achieve results using the ICDAS-<br />

II system that were comparable to that of the examiner<br />

carrying out the training. The ICDAS-II system demonstrated<br />

reproducibility and diagnostic accuracy for the<br />

detection of occlusal caries at varying stages of the disease<br />

process comparable to those published in previous<br />

studies using similar visual criteria. The moderate to<br />

strong relationship with histological extent also demonstrates<br />

its potential to monitor lesions with time. With the<br />

development of more extensive and advanced training<br />

packages and calibration exercises there may be scope to<br />

improve the reproducibility and accuracy further. In addition,<br />

such packages would allow further dissemination<br />

of ICDAS-II, allowing data from clinical studies in primary<br />

dental care, clinical trials and epidemiological surveys<br />

to have greater clarity and comparability for metaanalyses.<br />

References<br />

Bader JD, Shugars DA: A systematic review of the<br />

performance of a laser fluorescence device<br />

for detecting caries. J Am Dent Assoc 2004;<br />

135: 1413–1426.<br />

Bader JD, Shugars DA, Bonito AJ: Systematic reviews<br />

of selected dental caries diagnostic and<br />

management methods. J Dent Educ 2001; 65:<br />

960–968.<br />

Chesters RK, Pitts NB, Matuliene G, Kvedariene<br />

A, Huntington E, Bendinskaite R, Balciuniene<br />

I, Matheson JR, Nicholson JA, Gendvilyte<br />

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trial design validated over 24 months. J<br />

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Downer MC: Concurrent validity of an epidemiological<br />

diagnostic system for caries with<br />

the histological appearance of extracted<br />

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Downer MC: Validation of methods used in dental<br />

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Ekstrand KR, Kuzmina I, Bjørndal L, Thylstrup<br />

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Ekstrand KR, Ricketts DN, Kidd EA: Reproducibility<br />

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caries: pathology, diagnosis and logical management.<br />

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Fyffe HE, Deery CH, Nugent ZJ, Nuttall NM,<br />

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2000a;28: 42–51.<br />

Fyffe HE, Deery C, Nugent ZJ, Nuttall NM, Pitts<br />

NB: In vitro validity of the Dundee Selectable<br />

Threshold Method for caries diagnosis<br />

(DSTM). Community Dent Oral Epidemiol<br />

2000b;28: 52–58.<br />

Ie YL, Verdonschot EH: Performance of diagnostic<br />

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compared. Community Dent Oral Epidemiol<br />

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Ismail AI: Visual and visuo-tactile detection of<br />

dental caries. J Dent Res 2004; 83(special No<br />

C):C56–C66.<br />

Longbottom C, Huysmans MC: Electrical measurements<br />

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Dent Res 2004; 83(special No C):C76–C79.<br />

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Caries Res 2008;42:79–87<br />

Jablonski-Momeni /Stachniss /Ricketts /<br />

Heinzel-Gutenbrunner /Pieper

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