atrial fibrillation and stroke prevention - Continuing Medical ...
atrial fibrillation and stroke prevention - Continuing Medical ...
atrial fibrillation and stroke prevention - Continuing Medical ...
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Essentials in Primary Care Conference<br />
Wednesday, July 31, 2013<br />
Balancing the Risk of Stroke Vs Bleeding:<br />
Risk of ICH is Very Low when INR Between 2 <strong>and</strong> 3<br />
20<br />
Ischemic <strong>stroke</strong><br />
Odds Ratio<br />
15<br />
10<br />
5<br />
IDEAL<br />
Intracranial hemmorhage (ICH)<br />
1<br />
1.0 2.0 3.0 4.0 5.0 6.0 7.0 8.0<br />
INR<br />
Fuster et al. J Am Coll Cardiol. 2001;38:1231-1265.<br />
Hylek et al. Ann Intern Med. 1994;120:897-902.<br />
Intracranial Hemorrhage During Long-<br />
Term Anticoagulation With Warfarin<br />
ICH %/Year<br />
2.0<br />
1.8<br />
1.6<br />
1.4<br />
1.2<br />
1.0<br />
0.8<br />
0.6<br />
0.4<br />
0.2<br />
INR<br />
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