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DEVELOPING OUR<br />
ORGANISATION<br />
Using our resources efficiently and effectively.<br />
TAKING STOCK<br />
A rapid response minimised the<br />
impact of the global financial crisis<br />
on the <strong>Wellcome</strong> <strong>Trust</strong>’s asset base.<br />
With financial markets looking vulnerable,<br />
in 2008 the <strong>Trust</strong> moved swiftly to protect<br />
the value of its investment portfolio. It<br />
expanded its equity sale programme<br />
from £3 billion to a total of over £4.5bn<br />
and disposed of certain other assets,<br />
generating record levels of cash holdings.<br />
While this provided considerable<br />
protection from the year’s turmoil, the<br />
depth of the financial crisis led to a net<br />
fall in the <strong>Trust</strong>’s investment asset base<br />
to £13.1bn at 30 September 2008, a<br />
drop of 10.8 per cent over the year.<br />
This compares favourably with the falls<br />
in global and UK equities of 16 per<br />
cent and 21 per cent, respectively.<br />
Ten-year returns for equities have<br />
reached their lowest levels since the<br />
US War of Independence in the 1770s.<br />
With equities now offering relatively<br />
good value, the <strong>Trust</strong> has begun to<br />
reinvest, while maintaining sufficient<br />
reserves of cash to support charitable<br />
activities without having to dispose<br />
of assets at distressed prices.<br />
Overall, the <strong>Trust</strong>’s financial position<br />
remains strong. Since the flotation of<br />
<strong>Wellcome</strong> plc in October 1985, returns<br />
have averaged 14.9 per cent a year,<br />
considerably exceeding both the global<br />
equity index and the <strong>Trust</strong>’s targeted<br />
return (6 per cent real returns).<br />
A HIGHER PROFILE<br />
The <strong>Wellcome</strong> <strong>Trust</strong> has been<br />
a keen participant in global<br />
health discussions.<br />
Although UK-based, the <strong>Wellcome</strong> <strong>Trust</strong><br />
has an international agenda. It funds<br />
considerable research in developing<br />
countries and has played a pivotal role<br />
in numerous international consortia.<br />
Human health is an international issue.<br />
This year, the <strong>Trust</strong> has been involved<br />
in multilateral discussions to develop a<br />
road map for avian influenza research,<br />
spanning vaccine and drug development,<br />
surveillance and epidemiology. Fred<br />
Hayden, seconded from the University<br />
of Virginia, has been appointed to<br />
coordinate this work and is spending one<br />
week a month at the <strong>Trust</strong>’s offices.<br />
The <strong>Trust</strong> is also in discussion with the<br />
WHO about a coordinated distribution<br />
policy for vaccines and drugs, should an<br />
avian influenza pandemic break out.<br />
ACTIVE ENGAGEMENT<br />
More efforts are being made to<br />
engage with the scientific community.<br />
While response-mode funding remains<br />
core to the <strong>Trust</strong>’s work, more proactive<br />
strategies are also being developed.<br />
Central to this approach has been<br />
the recruitment of senior scientific<br />
figures. Recent years have seen the<br />
arrival of Professor Richard Morris,<br />
a leading neuroscientist from the<br />
University of Edinburgh, and Dr Alan<br />
Schafer, a geneticist and former head<br />
of GlaxoSmithKline’s Technology<br />
Development Department.<br />
With other senior scientific staff, Pat<br />
Goodwin and Jimmy Whitworth, they<br />
have set out to build stronger links with<br />
the research community and other key<br />
groups. The aim has been to gather input<br />
on the possible ways in which the <strong>Trust</strong><br />
can act catalytically to drive forward<br />
fields of research and application of new<br />
knowledge into practical benefits.<br />
The <strong>Trust</strong> has been active in organising<br />
Frontiers Meetings, bringing together<br />
key individuals to discuss emerging and<br />
important areas, including, in 2007/08,<br />
autism research and the ethics of<br />
genome-wide analyses.<br />
With a diverse portfolio of funding<br />
schemes, including response-mode<br />
grants, Strategic Awards and special<br />
initiative funding, the <strong>Trust</strong> is well placed<br />
to take these new ideas forward.