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DEVELOPING OUR<br />

ORGANISATION<br />

Using our resources efficiently and effectively.<br />

TAKING STOCK<br />

A rapid response minimised the<br />

impact of the global financial crisis<br />

on the <strong>Wellcome</strong> <strong>Trust</strong>’s asset base.<br />

With financial markets looking vulnerable,<br />

in 2008 the <strong>Trust</strong> moved swiftly to protect<br />

the value of its investment portfolio. It<br />

expanded its equity sale programme<br />

from £3 billion to a total of over £4.5bn<br />

and disposed of certain other assets,<br />

generating record levels of cash holdings.<br />

While this provided considerable<br />

protection from the year’s turmoil, the<br />

depth of the financial crisis led to a net<br />

fall in the <strong>Trust</strong>’s investment asset base<br />

to £13.1bn at 30 September 2008, a<br />

drop of 10.8 per cent over the year.<br />

This compares favourably with the falls<br />

in global and UK equities of 16 per<br />

cent and 21 per cent, respectively.<br />

Ten-year returns for equities have<br />

reached their lowest levels since the<br />

US War of Independence in the 1770s.<br />

With equities now offering relatively<br />

good value, the <strong>Trust</strong> has begun to<br />

reinvest, while maintaining sufficient<br />

reserves of cash to support charitable<br />

activities without having to dispose<br />

of assets at distressed prices.<br />

Overall, the <strong>Trust</strong>’s financial position<br />

remains strong. Since the flotation of<br />

<strong>Wellcome</strong> plc in October 1985, returns<br />

have averaged 14.9 per cent a year,<br />

considerably exceeding both the global<br />

equity index and the <strong>Trust</strong>’s targeted<br />

return (6 per cent real returns).<br />

A HIGHER PROFILE<br />

The <strong>Wellcome</strong> <strong>Trust</strong> has been<br />

a keen participant in global<br />

health discussions.<br />

Although UK-based, the <strong>Wellcome</strong> <strong>Trust</strong><br />

has an international agenda. It funds<br />

considerable research in developing<br />

countries and has played a pivotal role<br />

in numerous international consortia.<br />

Human health is an international issue.<br />

This year, the <strong>Trust</strong> has been involved<br />

in multilateral discussions to develop a<br />

road map for avian influenza research,<br />

spanning vaccine and drug development,<br />

surveillance and epidemiology. Fred<br />

Hayden, seconded from the University<br />

of Virginia, has been appointed to<br />

coordinate this work and is spending one<br />

week a month at the <strong>Trust</strong>’s offices.<br />

The <strong>Trust</strong> is also in discussion with the<br />

WHO about a coordinated distribution<br />

policy for vaccines and drugs, should an<br />

avian influenza pandemic break out.<br />

ACTIVE ENGAGEMENT<br />

More efforts are being made to<br />

engage with the scientific community.<br />

While response-mode funding remains<br />

core to the <strong>Trust</strong>’s work, more proactive<br />

strategies are also being developed.<br />

Central to this approach has been<br />

the recruitment of senior scientific<br />

figures. Recent years have seen the<br />

arrival of Professor Richard Morris,<br />

a leading neuroscientist from the<br />

University of Edinburgh, and Dr Alan<br />

Schafer, a geneticist and former head<br />

of GlaxoSmithKline’s Technology<br />

Development Department.<br />

With other senior scientific staff, Pat<br />

Goodwin and Jimmy Whitworth, they<br />

have set out to build stronger links with<br />

the research community and other key<br />

groups. The aim has been to gather input<br />

on the possible ways in which the <strong>Trust</strong><br />

can act catalytically to drive forward<br />

fields of research and application of new<br />

knowledge into practical benefits.<br />

The <strong>Trust</strong> has been active in organising<br />

Frontiers Meetings, bringing together<br />

key individuals to discuss emerging and<br />

important areas, including, in 2007/08,<br />

autism research and the ethics of<br />

genome-wide analyses.<br />

With a diverse portfolio of funding<br />

schemes, including response-mode<br />

grants, Strategic Awards and special<br />

initiative funding, the <strong>Trust</strong> is well placed<br />

to take these new ideas forward.

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