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56 | acknowledgements<br />
Acknowledgements<br />
We are grateful to everyone who agreed<br />
to be reviewed in this issue, everyone<br />
who supplied images or gave us<br />
permission for their images to be used,<br />
and the many members of <strong>Wellcome</strong><br />
<strong>Trust</strong> staff who helped to produce this<br />
volume.<br />
Editor<br />
Ian Jones, Isinglass Consultancy<br />
Project Manager<br />
Lucy Moore<br />
Writers<br />
Penny Bailey<br />
Ian Jones<br />
Mun-Keat Looi<br />
Editorial staff<br />
Tom Freeman<br />
Design<br />
Anja Fouad<br />
Photography<br />
David Sayer<br />
Mark Jones (Malawi images)<br />
Publisher<br />
Hugh Blackbourn<br />
Comments on the <strong>Wellcome</strong> <strong>Trust</strong><br />
Annual Review are welcomed and<br />
should be sent to:<br />
Hugh Blackbourn<br />
Publishing Department<br />
<strong>Wellcome</strong> <strong>Trust</strong><br />
Gibbs Building<br />
215 Euston Road<br />
London NW1 2BE, UK<br />
F +44 (0)20 7611 8270<br />
E publishing@wellcome.ac.uk<br />
The <strong>Wellcome</strong> <strong>Trust</strong> Annual Review is<br />
distributed via a mailing list held by the<br />
<strong>Wellcome</strong> <strong>Trust</strong>. If you would like to be<br />
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contact:<br />
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FREEPOST<br />
RLYJ-UJHU-EKHJ<br />
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T +44 (0)20 7611 8651<br />
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E publishing@wellcome.ac.uk<br />
www.wellcome.ac.uk/publications<br />
ISBN 978 1 84129 081 2<br />
The <strong>Wellcome</strong> <strong>Trust</strong> is a charity<br />
registered in England, no. 210183. Its<br />
sole trustee is The <strong>Wellcome</strong> <strong>Trust</strong><br />
Limited, a company registered in<br />
England, no. 2711000, whose registered<br />
office is at 215 Euston Road, London<br />
NW1 2BE, UK.<br />
First published by the <strong>Wellcome</strong> <strong>Trust</strong>,<br />
2009.<br />
© The trustee of the <strong>Wellcome</strong> <strong>Trust</strong>,<br />
London.<br />
This is an open access publication and,<br />
with the exception of images and<br />
illustrations, the content may, unless<br />
otherwise stated, be reproduced free of<br />
charge in any format or medium, subject<br />
to the following conditions: content must<br />
be reproduced accurately; content must<br />
not be used in a misleading context; the<br />
<strong>Wellcome</strong> <strong>Trust</strong> must be attributed as the<br />
original author and the title of the<br />
document specified in the attribution.<br />
<strong>Wellcome</strong> <strong>Trust</strong><br />
Gibbs Building<br />
215 Euston Road<br />
London NW1 2BE, UK<br />
T +44 (0)20 7611 8888<br />
F +44 (0)20 7611 8545<br />
E contact@wellcome.ac.uk<br />
www.wellcome.ac.uk<br />
All images are courtesy of <strong>Wellcome</strong> Images<br />
(http://images.wellcome.ac.uk) except as follows:<br />
Contents and p. 1: 2 (D Furness), 6 (A Weston);<br />
pp. 2–3: 1 (A Cavanagh); pp. 6–7: 1 (adapted from<br />
Chamberlain et al., reproduced with permission from<br />
AAAS), 2 (I van Bussel), 3 (A Weston), 4 (A Cavanagh);<br />
pp. 8–9: 1 (from Wang et al., reproduced with<br />
permission from AAAS), 2 (Medical Microscopy<br />
Sciences, Cardiff University); pp. 10–11: 1 (D Furness),<br />
2 (MRC NIMR), 3, 4 (from Abrahamsen et al.,<br />
reproduced with permission from AAAS), 5, 6<br />
(L Trinkle-Mulcahy); pp. 12–13: 1 (E Martino/Panos);<br />
pp. 14–15: ion channel (P Stansfeld, M Sansom,<br />
F Ashcroft/OXION); pp. 18–19: 2 (K Whitley);<br />
pp. 20–21: 1 (D Scharf/SPL), 2 (from Plouffe et al.,<br />
reproduced with permission from PNAS), 3, 4 (from<br />
Newton et al., reproduced with permission from<br />
PLoS Medicine); pp. 22–23: 1 (W Page/Panos),<br />
2 (N Durrell McKenna), 3 (A Vardhan/iStockphoto),<br />
4 (S Schuller), protein structure (B Marsden/Structural<br />
Genomics Consortium); pp. 26–27: 3 (Windfall Films);<br />
pp. 28–29: 1 (Cardboard Citizens/Robert Day),<br />
2 (Media <strong>Trust</strong> Productions), Science Gallery (Science<br />
Gallery Dublin); p. 31: 1 (Rex Features), 3 (S Nosten);<br />
pp. 32–33: 1 (from Mangale et al., reproduced with<br />
permission from AAAS), 2 (O Burston); pp. 34–35: 1<br />
(M Terao/iStockphoto), 2 (I Macrae); p. 37: 1 (S Klein/<br />
iStockphoto), 2 (iStockphoto); pp. 38–39: 1 (T Lang),<br />
2 (Y Nikas); p. 46: top left (A Tanczos), top right<br />
(Y Nikas), centre left (A Cavanagh), centre right<br />
(University of Edinburgh), bottom left (MI Walker),<br />
bottom right (D Furness); p. 47: top left (A Boyde), top<br />
right (D Furness), centre right (A Sieveking), bottom left<br />
(C Riley); p. 48 (A Cavanagh).<br />
Cover image:<br />
Salbutamol crystals. Salbutamol is used in inhalers<br />
for conditions where there is a narrowing of the<br />
airways, such as bronchitis, asthma and emphysema.<br />
The cluster of crystals is about 600 μm in diameter.<br />
Annie Cavanagh<br />
Cert no. SGS-COC-2524<br />
Printed by the colourhouse using their pureprint ® environmental print<br />
technology. The printing inks are made from vegetable-based oils and 95<br />
per cent of cleaning solvents are recycled for further use. The colourhouse is<br />
a carbon-neutral company, accredited with environmental management<br />
system ISO 14001. This document was printed on material made from 25 per<br />
cent post-consumer waste, 25 per cent pre-consumer waste and 50 per<br />
cent virgin fibre from Forest Stewardship Council Mixed Sources and was<br />
manufactured at a mill with ISO 14001.<br />
DO-4306.2/8.5K/01-2009/AF