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Lessons from Micronutrient Studies in Patients with Glucose ...

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Reported Beneficial Effects<br />

of Chromium Supplementation<br />

Steroid-<strong>in</strong>duced <strong>in</strong>duced diabetes<br />

• 47 out of 50 patients improved <strong>with</strong> 600 µg Cr as<br />

CrPic for 14 d<br />

Rav<strong>in</strong>a et al, J Trace Elem Exp Med 12: 375, 2000<br />

Gestational diabetes<br />

• 4 and 8 µg Cr/kg as CrPic for 8 wk decreased<br />

fast<strong>in</strong>g <strong>in</strong>sul<strong>in</strong>, glucose and <strong>in</strong>sul<strong>in</strong> conc. . dur<strong>in</strong>g OGTT<br />

• With severe glucose <strong>in</strong>tolerance, Cr did not reduce<br />

<strong>in</strong>sul<strong>in</strong> requirement<br />

Jovanovic et al, J Trace Elem Exp Med 12: 91, 1999

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