Lessons from Micronutrient Studies in Patients with Glucose ...

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Cr Supplementation and Human Diabetes: Summary Doses of Cr > 200 µg/d as CrPic elicit positive effects Increased insulin sensitivity Improved diabetic control fasting glucose fasting insulin HbA1C No relationship between serum Cr and diabetic control
Activation of Insulin Receptor Activity by Chromium apo chromodulin IR I Cr +3 Cr +3 -Transferrin IR I Insulin-sensitive sensitive cell Insulin receptor activated chromodulin [insulin] in blood apochromodulin +3 + 4 Cr +3 K f ~ 10 18 m M -1 chromodulin Urine IR I K m ~ 250 pM IR I Insulin receptor fully activated Chromodulin loaded with Cr Adapted from Vincent, J Nutr 130:715, 2000
Page 1 and 2: Lessons from Micronutrient Studies
Page 3 and 4: Chromium and Glucose/Insulin: Hypot
Page 5 and 6: Chromium Supplementation in Type II
Page 7 and 8: Effects of Chromium on Fasting Insu
Page 9 and 10: 180 Reduced Fasting Glucose with *
Page 11: Reported Beneficial Effects of Chro
Page 15 and 16: Vanadium in Glucose Metabolism and
Page 17 and 18: Vanadyl Sulfate: Diabetic Control H
Page 19 and 20: 1200 Serum Vanadium Concentrations
Page 21 and 22: V Supplementation and Human Diabete
Page 23 and 24: Adverse Effects of Cr & V Supplemen

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