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<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

1


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<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

3


Here&Now August<br />

2012 • Volume 3, Issue 8<br />

25 Hyperglycemia in<br />

the Hospital Setting<br />

When it comes to inpatient<br />

management of insulin levels,<br />

appropriate protocol selection<br />

is often a key decision in the<br />

course of hospital care. Heidi<br />

Rymaszewski, ANP-BC, BC-ADM,<br />

CDE, uses a case presentation<br />

to illustrate this essential point.<br />

25<br />

Columns & Departments<br />

First & Foremost ..............................6<br />

Front & Center ................................8<br />

Role & Growth ...............................10<br />

Calendar ...................................29<br />

Ad Index ...................................33<br />

Career Opportunities ..........................38<br />

Comments & Feedback ........................50<br />

Articles<br />

12 Head Lice Update<br />

It’s back-to-school time and that often means head lice outbreaks. Kara<br />

L. Caruthers, MSPAS, PA-C, and Patricia Jennings, DrPH, PA-C, describe<br />

the life cycle of head lice and how these organisms can be removed.<br />

(cover image by John Ciuppa/Doris Mohr)<br />

15<br />

21<br />

15 Patient Care<br />

Issues in Mild TBI<br />

This month’s CME/CE article<br />

provides in<strong>for</strong>mation on mild<br />

traumatic brain injury, which is<br />

diagnosed more often today<br />

thanks to better understanding<br />

and recognition. Karen Williams,<br />

MSN, CRNP, outlines diagnostic<br />

criteria and treatment strategies.<br />

21 Symptom Overlap<br />

in the Irritable Bowel<br />

Irritable bowel syndrome is a<br />

functional bowel disorder whose<br />

symptoms can be confused with<br />

those of gluten sensitivity and<br />

celiac disease. Susan Andersen,<br />

PhD, RN, FNP-BC, explains how<br />

to decipher symptom overlap<br />

through careful history taking.<br />

The new season of <strong>ADVANCE</strong> Job Fairs &<br />

Career Events is here!<br />

Register now <strong>for</strong> your chance to meet recruiters in your<br />

area, attend top-notch sessions and enter to win prizes like<br />

a $500 Visa gift card! Visit www.advanceweb.com/events<br />

to see our complete schedule of FREE in-person and online<br />

events.<br />

Copyright 2012 by Merion Matters. All rights reserved. Reproduction in any <strong>for</strong>m is <strong>for</strong>bidden without written<br />

permission of publisher. <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong> (ISSN 1096-6293) is published monthly by Merion<br />

Publications, Inc., 2900 Horizon Drive, Box 61556, King of Prussia, PA 19406-0956.<br />

Periodicals Postage Paid at Norristown, PA and additional mailing offices. Postmaster: send address changes<br />

to: <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong>, Circulation Department, Merion Publications, Inc.,<br />

2900 Horizon Drive, Box 61556, King of Prussia, PA 19406-0956.<br />

websites <strong>for</strong> health in<strong>for</strong>mation professionals, healthcare executives, hearing<br />

healthcare professionals, imaging and radiation oncology professionals,<br />

laboratory administrators, long-term care managers and professionals, medical<br />

laboratory professionals, nurse practitioners and physician assistants,<br />

nurses, occupational therapy practitioners, physical therapy and rehabilitation<br />

professionals, respiratory care and sleep medicine professionals, and speechlanguage<br />

pathologists and audiologists.<br />

Please Recycle This Magazine<br />

®<br />

Advance is a member of the National Association <strong>for</strong> Health Care Recruitment.<br />

<strong>ADVANCE</strong> is free to certified nurse practitioners and physician assistants<br />

and students with senior status. Our company serves the in<strong>for</strong>mational and<br />

career needs of doctors, nurses and allied healthcare professionals through a<br />

wide range of products and services, including magazines, e-newsletters and<br />

<strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong> is the official publication of the Association of Family<br />

Practice Physician Assistants.<br />

<strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong> is an official journal of the National Academy of<br />

Dermatology Nurse Practitioners.<br />

4 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


Now at<br />

advanceweb.com/NPPA<br />

FREE<br />

yearly<br />

subscription.<br />

PA Response Breakdown<br />

This month, get the complete breakdown of<br />

physician assistant responses to the 2011<br />

National Salary Survey of <strong>NPs</strong> & <strong>PAs</strong>. (The nurse<br />

practitioner breakdown went live in July.) Find the<br />

report in the Salary In<strong>for</strong>mation section of our<br />

homepage. Please complete the 2012 survey while<br />

you're there!<br />

FREE<br />

online resources.<br />

FREE<br />

access to so<br />

much more.<br />

Don’t miss these<br />

upcoming<br />

issue features:<br />

• Geriatrics: Dementia<br />

• Concussions in<br />

Soldiers<br />

• CME/CE on<br />

HIV/AIDS<br />

• Reproductive Health<br />

Issues in Women<br />

• Technology in<br />

Clinical Care<br />

Don’t miss these<br />

upcoming online<br />

features:<br />

• Coverage from Major<br />

Conferences<br />

• Current Issues in Asthma<br />

• Women’s Health<br />

• Diabetes<br />

• Back-to-School<br />

Health Issues<br />

• Professional Issues Webinar<br />

A Study of Acute Care <strong>NPs</strong><br />

Visit our website starting Aug. 2 <strong>for</strong> an article about<br />

a study of acute care practice by <strong>NPs</strong> in Florida. The<br />

author sought to determine the procedure competencies<br />

and job functions unique to acute care <strong>NPs</strong> in Florida<br />

and to compare these findings to those obtained in a<br />

2001 national survey of the same skills. Find the article<br />

by entering the author’s name, “Jo Ann Kleier,” in the<br />

Search Articles box on our homepage.<br />

Don’t miss all that <strong>ADVANCE</strong> offers!<br />

Subscribe or renew today – it’s quick and easy.<br />

• Call 800-355-1088 (M-F, 8am-6pm ET)<br />

• Visit www.advanceweb.com/nppa<br />

• Snap the tag to the right<br />

<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

5


First&Foremost<br />

is published by Merion Matters<br />

Publishers of leading healthcare magazines since 1985.<br />

Joining Forces<br />

Nurse practitioners and physician assistants are<br />

heavily involved in the Joining Forces initiative <strong>for</strong> military veterans<br />

and their families. This program (http://www.whitehouse.gov/joining<strong>for</strong>ces)<br />

reaches out to service members and their families with<br />

resources <strong>for</strong> employment, education and wellness.<br />

A new ef<strong>for</strong>t to “join <strong>for</strong>ces” is taking shape in the nurse<br />

practitioner profession. The boards of the American Academy<br />

of Nurse Practitioners (AANP) and the American College of<br />

Nurse Practitioners (ACNP) recently voted to work toward<br />

consolidation as one national group representing <strong>NPs</strong> in all specialties. As someone<br />

who has observed and reported on these esteemed organizations <strong>for</strong> 19 years,<br />

I applaud this decision.<br />

And based on the feedback we received as soon as we posted this news on our website<br />

and social media, many <strong>NPs</strong> feel the same way: “This is a wonderful opportunity <strong>for</strong><br />

there is strength in numbers” … “I am excited about the possibilities associated with<br />

this merger” … “This couldn’t come at a better time. We need one voice.”<br />

We at <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong> echo these reader comments and wish the two<br />

boards of directors well as they navigate this complex process. Read more about<br />

the planned consolodation in this month’s news section (Front & Center, page 8).<br />

Did you know <strong>ADVANCE</strong> has been supporting <strong>NPs</strong> and <strong>PAs</strong> by publishing free<br />

peer-reviewed content specifically <strong>for</strong> your professions since 1993 Other journals<br />

in this market are moving toward subscription fees, but <strong>ADVANCE</strong> will not do that.<br />

Please help us ensure that our publication remains available free of charge by renewing<br />

or subscribing today. The U.S. Postal Service requires that we receive your official<br />

request each year. We will no longer be able to extend your subscription beyond the<br />

expiration date, as we have in the past.<br />

Time is running out <strong>for</strong> you to renew or add your name to our mailing list or digital<br />

subscriber list. Please call our Subscriber Services department at 800-355-1088<br />

or choose the “Subscribe” button at the top right corner of our homepage, www.<br />

advanceweb.com/NPPA. ■<br />

— Michelle Perron Pronsati<br />

Publisher<br />

Ann Wiest Kielinski<br />

General Manager<br />

W. M. “Woody” Kielinski<br />

Chief In<strong>for</strong>mation Officer<br />

Khader Mohammed<br />

Editorial Staff<br />

Editor: Michelle Perron Pronsati<br />

Senior Associate Editor: Jennifer Ford<br />

Editorial Assistant: Kelly Wolfgang<br />

Web Manager: Jennifer Montone<br />

Design<br />

Vice President, Director of Creative Services:<br />

Susan Basile<br />

Design Director: Walt Saylor<br />

Art Director: Doris Mohr<br />

Multimedia Director: Todd Gerber<br />

advertising<br />

Director of Marketing Services: Christina Allmer<br />

Art Director: Chris Wof<strong>for</strong>d<br />

EVENTS<br />

Public Relations Director: Maria Senior<br />

Job Fair Manager: Laura Smith<br />

Events Product Manager: Mike Connor<br />

ADMINISTRATION<br />

Vice President, Director of Human Resources:<br />

Jaci Nicely<br />

In<strong>for</strong>mation & Business Systems Director:<br />

Ken Nicely<br />

Digital Media Sales Director: Kim Noble<br />

Circulation Manager: Maryann Kurkowski<br />

Billing Manager: Christine Marvel<br />

Subscriber Services Manager: Vikram Khambatta<br />

Media & Marketing Opportunities<br />

Display Advertising<br />

Sales Director: Amy Turnquist<br />

National Account Executive: Shannon Ferguson<br />

Sales Associate: Ashley Hackett<br />

Healthcare Facility Advertising<br />

Sales Director: Kim Noble<br />

Group Manager: Robert Murray<br />

Education Advertising<br />

Sales Manager: Ed Zeto<br />

Senior Account Executive: Brock Bamber<br />

Account Executive: Sarah Rucinski<br />

CUSTOM PROMOTIONs<br />

Sales Manager: Mike Kerr<br />

Senior Account Executives: Noel Lopez,<br />

Sue Borjeson-Romano<br />

Sales Associates: Kristen Erskine, Danielle LaSorda,<br />

Desirae Slaugh, Gina Willett<br />

How to Contact Us<br />

The Editor Recommends …<br />

➼ Data collection <strong>for</strong> the 2012 National Salary Survey is under way. Have you<br />

filled out the survey yet Make sure your specialty, practice setting and geographic<br />

area are accurately represented. Visit our website to access the survey link in the<br />

"Salary In<strong>for</strong>mation" box near the top of the homepage.<br />

• For a FREE subscription: Call (800) 355-1088 or<br />

sign up at www.advanceweb.com/NPPA<br />

• To reach the editor:<br />

Michelle Perron Pronsati, mpronsati@<br />

advanceweb.com or (800) 355-5627, Ext. 1221<br />

• To reach the senior associate editor and<br />

website editor:<br />

Jennifer Ford, j<strong>for</strong>d@advanceweb.com or<br />

(800) 355-5627, Ext. 1384<br />

• To reach the editorial assistant: Kelly Wolfgang,<br />

kwolfgang@advanceweb.com, Ext. 1158<br />

• To order article reprints: (800) 355-5627, Ext.<br />

1446<br />

• To place an advertisement (display, calendar or<br />

recruitment): (800) 355-5627, Ext. 0<br />

<strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong><br />

Merion Matters • 2900 Horizon Dr.<br />

King of Prussia PA 19406<br />

6 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


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<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

7


Front&Center<br />

By Kelly Wolfgang<br />

News <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong><br />

AANP and ACNP Plan to Consolidate<br />

The boards of directors <strong>for</strong> the American Academy<br />

of Nurse Practitioners (AANP) and the American College<br />

of Nurse Practitioners (ACNP) recently announced plans to<br />

consolidate the two organizations. In a press release issued<br />

in July, the boards stated that the merger would result in a<br />

national nurse practitioner organization with aligned goals<br />

<strong>for</strong> policy change, healthcare re<strong>for</strong>m, professional growth,<br />

education and research.<br />

“AANP is excited at the prospect of combining <strong>for</strong>ces with<br />

ACNP. Aligning our organizations gives us the ability to speak<br />

and advocate <strong>for</strong> nurse practitioners with one collective voice.<br />

There has never been a better time <strong>for</strong> the consolidation of our<br />

organizations,” AANP president Angie Golden, DNP, FNP-C,<br />

FAANP, told <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong>.<br />

At the time this issue went to press, no further details about<br />

the consolidation plan were available. <strong>ADVANCE</strong> will continue<br />

to report on the consolidation ef<strong>for</strong>t as it evolves.<br />

AANP Conference Attendance Tops 4,300<br />

ORLANDO, Fla. — The American Academy of Nurse<br />

Practitioners (AANP) conference in Orlando, Fla., in June drew<br />

more than 4,300 <strong>NPs</strong> and NP students. The annual event focused<br />

on healthcare policy and the support of military members.<br />

At the opening session, keynote speaker James O. Prochaska,<br />

PhD, spoke about the impact of behavioral health. AANP has<br />

encouraged <strong>NPs</strong> to provide mental and physical care to current<br />

service members, veterans and their families through<br />

the Joining Forces initiative spearheaded by the White House.<br />

The first-ever Loretta C. Ford Award <strong>for</strong> Advancement<br />

of the Nurse Practitioner Role in Healthcare was presented<br />

to Joanne Pohl, PhD, ANP-BC, FAAN, FAANP, professor<br />

emeritus at the University of Michigan School of Nursing.<br />

The award was created in honor of Ford, who co-founded<br />

the NP profession.<br />

AANP’s director of health policy, Jan Towers, PhD, NP-C,<br />

CRNP, FAANP, FAAN, spoke about the importance of healthcare<br />

policy and encouraged <strong>NPs</strong> to reach out to their representatives<br />

and foster change. “Any way you slice it, there are<br />

Nurse practitioners gathered on the steps of the Orange County<br />

Convention Center <strong>for</strong> a white coat photo at the 2012 AANP conference.<br />

32 to 35 million patients without insurance, and <strong>NPs</strong> need to<br />

help,” Towers said. “... you need to step in to leadership roles<br />

in relation to that.”<br />

Also at the conference, past president Penny Kaye Jensen,<br />

DNP, APRN, FNP-C, FAANP, passed the gavel to current president<br />

Angie Golden, DNP, FNP-C, FAANP. Golden welcomed<br />

attendees and kicked off the opening of the conference.<br />

Attendees enjoyed sessions on topics such as genetics, medical<br />

Spanish, social media, reimbursement, immunization, smoking<br />

cessation, precepting and more. Workshops and seminars<br />

included suturing, sonographic technique, breast cancer risk<br />

assessment and pediatric autism spectrum disorders.<br />

To view photos from the conference, visit http://bit.ly/<br />

Nh4daq. The next AANP conference will be held June 19-23,<br />

2013, in Las Vegas.<br />

Delaney Takes Reins as<br />

AAPA President<br />

James Delaney, PA-C, recently began<br />

a 1-year term as president of the American<br />

Academy of Physician Assistants (AAPA).<br />

“I’m so pleased to take on this role because<br />

this is an exciting time <strong>for</strong> the PA profession.<br />

<strong>PAs</strong> are being recognized <strong>for</strong> their<br />

James Delaney,<br />

PA-C<br />

ability to increase access<br />

to quality, coordinated<br />

healthcare in virtually<br />

every medical setting<br />

and specialty,” Delaney<br />

said in a press release<br />

issued by the AAPA.<br />

“Now more than ever,<br />

increased awareness will be placed on the<br />

role and the value of the PA as an integral<br />

partner of the health care team,” Delaney<br />

said. “Our ongoing challenge is to keep the<br />

PA profession in the <strong>for</strong>efront of both state<br />

and federal legislators.” Delaney began<br />

his term as president-elect in June 2011.<br />

His term as president will expire in 2013.<br />

8 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


Front&Center<br />

AFPPA Backs Title Change<br />

The Association of Family Practice Physician Assistants<br />

(AFPPA) recently released a position statement in support of<br />

changing the word “assistant” in the PA name. In the statement,<br />

the AFPPA requests the establishment of a committee to determine<br />

a “reasonable and evolutionary way that would also allow<br />

members to realize that they have been heard and responded to<br />

regarding this long-standing problem.”<br />

“The AFPPA believes that the assistant<br />

part of the PA title presents the<br />

profession with a problem. On many<br />

levels the term assistant at best is confusing<br />

and tends to place the PA profession<br />

on a level that most consumers,<br />

legislators and executives associate<br />

with a trade school or community<br />

college degree,” the document states.<br />

“Especially in primary care, the word<br />

assistant connotes that the ‘assistant’ is<br />

the helper and you are helping/assisting<br />

someone else. More than any other<br />

specialty, our primary care membership<br />

sees patients autonomously, fully<br />

diagnosing and treating them. It may<br />

border on being untruthful to say that<br />

we assist someone when that person<br />

is not even present in the building.”<br />

Beth Smolko, PA-C, president of<br />

AFPPA, told <strong>ADVANCE</strong> that concerns<br />

about the cost of a name change<br />

are unfounded without backup. "We<br />

often hear the argument that the<br />

name change would cost too much<br />

and it might open holes in legislation<br />

to restrict our scope of practice. A<br />

research study has not been conducted<br />

to validate those arguments. Why<br />

would we not want to research a way<br />

to strengthen our profession"<br />

Members of the AAPA made a similar<br />

request at the organization’s 2012<br />

conference. After 2 days of debate, the<br />

House of Delegates voted it down. For<br />

more in<strong>for</strong>mation on the AFPPA and<br />

its position statement, visit http://<br />

www.afppa.org/.<br />

NCCPA Searches <strong>for</strong><br />

New President<br />

Following the July departure<br />

of Janet Lathrop as president and<br />

CEO of the National Commission on<br />

Certification of Physician Assistants (NCCPA), the board of<br />

directors has begun a search <strong>for</strong> a new leader. Pamela M. Dean,<br />

NCCPA chief operating officer, is serving as acting CEO. “We<br />

continue to move <strong>for</strong>ward with a commitment to providing<br />

excellent service to <strong>PAs</strong> seeking and maintaining certification<br />

while serving the public’s interest in all that we do,” said<br />

NCCPA chairperson Patricia Cook, MD, FACP. ■<br />

Making head lice<br />

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9


Role&Growth<br />

Accountable Care: Where<br />

Will <strong>NPs</strong> & <strong>PAs</strong> Fit In<br />

By Candace C. Harrington, DNP, ANP-BC, GNP-BC<br />

Accountable care organizations<br />

(ACOs) are more than a fad in the healthcare<br />

industry. In some <strong>for</strong>m, ACOs are<br />

part of our future as we transition from<br />

a volume- and intensity-driven model of<br />

care toward a value- and outcome-based<br />

system. The ACO focus on patient-centered<br />

care, based on standards of preventive,<br />

evidence-based and collaborative<br />

care, does not require a culture shift <strong>for</strong><br />

<strong>NPs</strong> and <strong>PAs</strong> who already embrace these<br />

practice philosophies. It is in our best<br />

interest to understand ACO concepts and<br />

their implications, regardless of setting.<br />

What is an ACO<br />

An initiative of the Patient Protection and<br />

Af<strong>for</strong>dable Care Act, ACOs are groups<br />

of providers who <strong>for</strong>m a healthcare network<br />

generally comprised of primary<br />

care physicians, <strong>NPs</strong>, <strong>PAs</strong>, specialists<br />

and hospitals. 1,2 An ACO must have a<br />

legal structure to distribute incentive<br />

payments to members within the ACO<br />

and a patient population of at least 5,000<br />

Medicare beneficiaries who are enrolled<br />

in Medicare Parts A and B. 1,2<br />

In an ACO, high-quality care delivered<br />

at low costs will result in high incentive<br />

payments, provided that the ACO also<br />

reins in growth in healthcare expenditures.<br />

3 A common thread in all ACO<br />

models is a primary care physician to<br />

oversee care coordination. 1,2 The extent of<br />

oversight may be variable based on design.<br />

Demonstration Projects<br />

Over the next 3 years, the Centers <strong>for</strong><br />

Medicare and Medicaid Services will conduct<br />

demonstration projects to identify<br />

the best design <strong>for</strong> ACOs. The Medicare<br />

Shared Savings Program <strong>for</strong> Accountable<br />

Care Organizations is a shared savings<br />

program that rewards providers with<br />

incentive payments <strong>for</strong> quality, cost and<br />

outcomes. Each network is accountable<br />

<strong>for</strong> its patient population. Success will be<br />

gauged on cost of care and approximately<br />

33 quality measures in four domains. 3<br />

These domains include patient experience,<br />

care coordination and patient safety, preventive<br />

health and at-risk populations. 3,4<br />

The Federally Qualified Health Center<br />

(FQHC) Advanced Primary Care Practice<br />

Demonstration evaluates the impact<br />

of advanced primary care practice on<br />

improving care, prevention, and reducing<br />

healthcare costs among Medicare beneficiaries<br />

served by FQHCs. 3 It will assess<br />

the impact that additional support has on<br />

the ability of FQHCs to trans<strong>for</strong>m their<br />

practice and become <strong>for</strong>mally recognized<br />

as patient-centered medical homes. 3<br />

The Advance Payment Accountable<br />

Care Organization Model will provide<br />

additional support to providers participating<br />

in the Medicare Shared Savings<br />

Program who also would benefit from<br />

additional start-up resources to build<br />

the necessary infrastructure, such as new<br />

staff or in<strong>for</strong>mation technology systems. 3<br />

The Pioneer Accountable Care<br />

Organization Model is complementary<br />

to the Medicare Shared Savings Program,<br />

designed <strong>for</strong> organizations that provide<br />

integrated care across settings. 2 The initial<br />

Pioneer sites will be positioned to rapidly<br />

demonstrate what can be achieved when<br />

we provide highly coordinated care to<br />

Medicare fee-<strong>for</strong>-service beneficiaries. 3<br />

Candace Harrington is an adult and gerontologic nurse practitioner who is<br />

a clinical assistant professor at East Carolina University College of Nursing and<br />

a member of the adjunct faculty at Vanderbilt University School of Nursing.<br />

ACO Success Factors<br />

◗ All stakeholders<br />

must be included<br />

when establishing<br />

an ACO. (This<br />

is a cooperative<br />

ef<strong>for</strong>t.)<br />

◗ Abandon economic incentives<br />

incompatible with the intent of an<br />

ACO. (Productivity is defined by<br />

quality of service, not quantity of<br />

service.)<br />

◗ Make in<strong>for</strong>mation technology a top<br />

priority. (Invest in computer training<br />

if you feel deficient.)<br />

◗ Assist in choosing an EHR with<br />

Health In<strong>for</strong>mation Exchange<br />

capabilities to communicate, track,<br />

analyze and improve patient care<br />

and outcomes.<br />

◗ Establish a meaningful set of quality<br />

measures to rate ACO metrics.<br />

◗ Realize that patients and their experiences<br />

are at the center of an ACO.<br />

Adapted from Spoerl S. 8 biggest mistakes<br />

an ACO can make. Becker’s Hospital Review.<br />

2012;2012(5):1,30-31.<br />

Ongoing Debate<br />

The decision to put ACO care coordination<br />

in the hands of physicians is controversial<br />

and the source of heated debate <strong>for</strong> <strong>NPs</strong><br />

and <strong>PAs</strong>. The ACO design may change<br />

as the demonstration projects progress.<br />

ACOs cannot succeed without buy-in and<br />

full participation of all healthcare team<br />

members and their patients. ■<br />

References<br />

1. Camper S. Accountable care organizations:<br />

Lights! cameras! but where is the action National<br />

Healthcare Re<strong>for</strong>m Magazine. http://www.healthcarere<strong>for</strong>mmagazine.com/article/accountable-careorganizations-lights-cameras.html<br />

2. Devers K, Berenson R. Timely analysis of immediate<br />

health policy issues: Can accountable care organizations<br />

improve the value of health care by solving the<br />

cost and quality quandaries Robert Wood Johnson<br />

Foundation Urban Institute. www.rwjf.org/files/<br />

research/acobrieffinal.pdf<br />

3. The Af<strong>for</strong>dable Care Act: Helping providers help<br />

patients. The Centers <strong>for</strong> Medicare and Medicaid<br />

Services ACO Menu of Options. https://www.cms.gov/<br />

Medicare/Medicare-Fee-<strong>for</strong>-Service-Payment/ACO/<br />

downloads/ACO-Menu-Of-Options.pdf<br />

4. Harrington C. Measuring success under a microscope.<br />

<strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong>. 2011;2(10):16.<br />

illustration Dave perillo<br />

10 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


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11


Pediatrics<br />

Head Lice<br />

Getting down to the nit of things<br />

By Kara L. Caruthers, MSPAS, PA-C, and Patricia R. Jennings, DrPH, PA-C<br />

12 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


Pediatrics<br />

John Ciuppa<br />

➼ Between 6 million and 12<br />

million infestations of head lice occur<br />

every year in the United States. 1 Children<br />

between the ages of 3 and 11 are the most<br />

often affected, with occurrence more<br />

frequently in girls. 1<br />

Although head lice pose no public<br />

health threat or transmission of disease,<br />

they are an expensive nuisance.<br />

Treatments, lost wages and school<br />

expenses total an estimated $1 billion<br />

annually — an amount almost three<br />

times the estimated expenditure in the<br />

1990s. 2 The direct and indirect costs of<br />

treatment could be reduced by ending<br />

the “no-nit” policies en<strong>for</strong>ced by most<br />

school systems and by delivering efficacious<br />

treatments.<br />

Current Issues<br />

Pediculus humanus capitus is a six-legged<br />

parasite that grows no larger than 2 mm<br />

or 3 mm. Each leg has claws that allow<br />

the organism to grasp a hair follicle. Head<br />

lice survive by feeding off human blood<br />

every 3 to 6 hours. In optimal conditions,<br />

adult lice can survive more than 3<br />

weeks. Pruritus of the scalp is the most<br />

common symptom of an infestation, a<br />

result of localized allergic reaction to<br />

the louse bites. An infestation may be<br />

present <strong>for</strong> 6 weeks be<strong>for</strong>e symptoms<br />

become evident. The female lice<br />

lay eggs, or nits, within ¼ inch<br />

of the scalp. These hatch in 5<br />

to 10 days. The adult stage<br />

is reached about 10 days<br />

after hatching. 1,3<br />

Head lice infestation<br />

has historically<br />

been associated<br />

with lack of personal<br />

hygiene, lack of cleanliness<br />

in the home environment<br />

and (erroneously) lower<br />

The direct and indirect<br />

costs of treatment could<br />

be reduced by ending the<br />

“no-nit” policies en<strong>for</strong>ced<br />

by most school systems<br />

and by delivering<br />

efficacious treatments.<br />

socioeconomic status. The truth is that<br />

head lice infestations affect 5% to 10%<br />

of school-age children across all facets<br />

of life; rates of infestations among black<br />

children are lower. 1,2<br />

Head lice are most commonly transmitted<br />

through direct contact with the hair<br />

of an infected person. Environments in<br />

which direct contact often occurs include<br />

school, home, sporting practices/events,<br />

camps and slumber parties. Although<br />

parents and schools have long recommended<br />

that children avoid sharing hats,<br />

scarves, coats, combs, brushes and bed<br />

linens to prevent head lice spread, these<br />

are uncommon <strong>for</strong>ms of transmission. 1,2<br />

In an attempt to curtail the transmission<br />

of head lice, the National Pediculosis<br />

Association advocates a “no nit” policy: 4<br />

screening children <strong>for</strong> head lice to identify<br />

any evidence of lice or nits and immediately<br />

removing students with nits or<br />

lice from class until a re-examination<br />

proves clearance.<br />

Given the $1 billion burden associated<br />

with treating head lice and missing school<br />

and work, is this the best policy The<br />

American Academy of Pediatrics, the<br />

National Association of School Nurses<br />

and the Centers <strong>for</strong> Disease Control and<br />

Prevention recommend that children<br />

return to class as soon as treatment has<br />

been provided. 1,2,4 The CDC goes a step<br />

Kara L. Caruthers is an assistant professor in the physician assistant program at the University<br />

of Alabama at Birmingham and works clinically in emergency medicine. Patricia R. Jennings<br />

is director of the physician assistant program at the University of Alabama at Birmingham and<br />

also serves as a professor. She works clinically in the Division of Infectious Diseases at the<br />

University of Alabama Medical Center and the Birmingham Veterans Affairs Medical Center. The<br />

authors have completed disclosure statements and report no relationships related to this article.<br />

further by stating that children should not<br />

be immediately dismissed from school after<br />

a positive lice finding; instead, they should<br />

be allowed to complete the school day. 1<br />

Head lice do not fly, hop or jump. They<br />

crawl through the head, staying close to<br />

the scalp <strong>for</strong> both warmth and access<br />

to their food source (blood). They usually<br />

do not survive longer than 48 hours<br />

when away from the host. 1,3 Nits cannot<br />

hatch and usually die within 7 days if<br />

the temperature is not comparable to<br />

that of the scalp. 1 These facts support<br />

recommendations <strong>for</strong> discontinuing nonit<br />

policies. The cost of unnecessary<br />

absenteeism exceeds the risks associated<br />

with head lice.<br />

Permethrin<br />

The longstanding pharmacologic treatment<br />

of choice <strong>for</strong> head lice infestation<br />

is permethrin 1% lotion. 5 Permethrin<br />

(Nix) is a pediculicide that has reported<br />

secondary ovicidal properties. It is indicated<br />

<strong>for</strong> patients older than 2 months.<br />

Permethrin lotion was introduced in 1986<br />

and has been available over the counter<br />

since 1990. 2 It is associated with low<br />

levels of toxicity. 2<br />

Be<strong>for</strong>e using permethrin, hair must be<br />

washed with a nonconditioning shampoo<br />

and towel dried. A sufficient amount of<br />

lotion must be applied to saturate the<br />

hair and scalp; it should be rinsed off<br />

after 10 minutes. Current labeling <strong>for</strong> the<br />

product recommends a routine second<br />

treatment 7 to 10 days later. 2<br />

In recent years, reports of treatment<br />

failure with this therapy have surfaced<br />

throughout the world. Experts initially<br />

believed that the treatment failures were<br />

due to user error (nonadherence or failure<br />

to properly comb out nits), but in the<br />

United States, treatment failure is mostly<br />

attributed to increased resistance as a<br />

result of overuse and <strong>for</strong>mula changes. 4,6<br />

Malathion<br />

Malathion 0.5% (Ovide), an organophosphate,<br />

is a prescription pediculicide with<br />

ovicidal properties. It is available in a<br />

lotion or gel, and studies show it is more<br />

<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

13


Pediatrics<br />

The most obvious drawback <strong>for</strong> the preferred utilization of malathion is cost,<br />

since it requires both an office visit and a prescription.<br />

efficacious that permethrin 1%. 4-7 No<br />

reports of resistance have been associated<br />

with the current U.S. <strong>for</strong>mulation of<br />

this drug. 6 Malathion 0.5% lotion is safe<br />

to use on patients older than 6, and the<br />

gel <strong>for</strong>mulation is safe to use on patients<br />

older than 2.<br />

To deliver this treatment, the lotion or<br />

gel is applied to dry hair and allowed to<br />

air dry. The lotion remains on the hair<br />

<strong>for</strong> 8 to 12 hours; the gel preparation<br />

remains on the hair <strong>for</strong> 30 minutes. The<br />

gel is associated with fewer odors, easier<br />

application and less likelihood of eye<br />

irritation because of diminished dripping.<br />

Studies show that the gel <strong>for</strong>mulation is as<br />

effective as the lotion <strong>for</strong>mulation, with<br />

similar rates of retreatment. 2,5,7<br />

The most obvious drawback <strong>for</strong> the<br />

preferred utilization of malathion is<br />

cost, since it requires both an office<br />

visit and a prescription. Potential side<br />

effects must also be considered. Because<br />

malathion is a cholinesterase inhibitor,<br />

the potential <strong>for</strong> respiratory depression<br />

with ingestion is concerning. The<br />

potential risk of inadvertent ingestion<br />

by young children in the home should<br />

be considered. 2 No such cases have been<br />

reported, however.<br />

Newer Agents<br />

Three other pharmacologic agents have<br />

been introduced over the last 3 years to<br />

address emerging resistance. Benzyl alcohol<br />

5% (Ulesfia) lotion was approved in<br />

2009 <strong>for</strong> use as a prescribed pediculicide<br />

<strong>for</strong> the treatment of head lice in patients<br />

older than 6 months and in pregnant<br />

women. The lotion is touted as nontoxic<br />

because it does not contain pesticides;<br />

malathion 0.5% and permethrin 1%<br />

do. Ulesfia has a unique mechanism<br />

of asphyxiating lice by “stunning” their<br />

external breathing component. 8<br />

Ulesfia lotion should be applied in<br />

sufficient quantity to cover all lice on<br />

the hair and scalp. The application is<br />

rinsed off after 10 minutes and must<br />

be repeated in 7 days. In clinical trials,<br />

head inspection 1 day after the second<br />

dose showed clearance rates of 92% or<br />

higher. 5,8 Development of resistance is<br />

thought to be unlikely with Ulesfia since<br />

the mechanism of action opens the external<br />

breathing pathway of the louse.<br />

Spinosad 0.9% (Natroba) is a cream rinse<br />

<strong>for</strong> patients older than 4; it was approved in<br />

2011. This product is a prescribed pediculicide<br />

that targets the nicotinic receptor<br />

of acetylcholine and the gamma aminobutyric<br />

(GABA) gated chloride channel<br />

of the louse, causing paralysis.<br />

The hair and scalp should be saturated<br />

with Natroba and left on <strong>for</strong> 10<br />

minutes. In clinical trials, most patients<br />

only needed one treatment. A second<br />

treatment can be given in 7 days if live<br />

lice are still present. Eighty-five percent<br />

of patients were lice-free 14 days after the<br />

final treatment. While spinosad 0.9% is<br />

neurotoxic to lice, it is thought to have<br />

fewer side effects than permethrin. 5<br />

Ivermectin lotion 0.5% (Sklice) is a lice<br />

treatment <strong>for</strong> patients older than 6 months;<br />

it was approved in February 2012. This<br />

lotion is a prescribed pediculicide that also<br />

works on the GABA chloride channels,<br />

causing paralysis and resulting in death<br />

of the louse. The lotion is applied to dry<br />

hair and to the scalp. The contents of the<br />

entire 4-gram tube should be applied. The<br />

product should remain on the hair and<br />

scalp <strong>for</strong> 10 minutes be<strong>for</strong>e being rinsed<br />

out. The current recommendation is <strong>for</strong><br />

use as a one-time treatment.<br />

Two trials of ivermectin lotion demonstrated<br />

71% to 76% lice eradication<br />

14 days after a single treatment. 9 Oral<br />

ivermectin has been used off label <strong>for</strong><br />

the treatment of head lice <strong>for</strong> some time.<br />

Safety concerns exist about crossing<br />

Head Lice Through the Years<br />

➼ find our archived coverage of head lice by entering the term in our Search<br />

box at www.advanceweb.com/NPPA.<br />

the blood–brain barrier and potential<br />

<strong>for</strong> neural transmission interruption in<br />

younger patients. 2<br />

Rethinking Policy<br />

Head lice infestations in school systems<br />

across the United States are a public health<br />

nuisance and an economic burden on<br />

families. Prolonged absenteeism from both<br />

school and work are unnecessary considering<br />

the lifespan and patterns of the human<br />

head louse. Several health organizations<br />

recommend an end to “no nit” policies in<br />

American school systems. Children should<br />

be allowed to return to the classroom once<br />

treatment has been initiated.<br />

Permethrin is still considered the<br />

treatment of choice <strong>for</strong> head lice, but<br />

increasing pesticide resistance warrants<br />

consideration of other treatment modalities.<br />

Malathion, benzyl alcohol, spinosad<br />

and ivermectin should be considered <strong>for</strong><br />

head lice treatment since these therapies<br />

can be more efficacious than permethrin.<br />

While copayments and prescriptions are<br />

burdensome <strong>for</strong> some, these costs may<br />

be worth it when weighed against the<br />

potential <strong>for</strong> prolonged absence from<br />

school and work. 4 ■<br />

References<br />

1. Centers <strong>for</strong> Disease Control and Prevention.<br />

Parasites-Lice-Headlice. www.cdc.gov/parasites/lice/<br />

head/index.htm.<br />

2. Frankowski BL, Bocchini JA. Head Lice. Pediatrics.<br />

2010;126(2):392-403.<br />

3. Texas A&M University. Louse. http://insects.<br />

tamu.edu/fieldguide/aimg37.html.<br />

4. Gur I, Schneeweiss R. Head lice treatments<br />

and school policies in the US in an era of emerging<br />

resistance: a cost-effectiveness analysis. J<br />

Pharmacoeconomics. 2009;27(9):725-734.<br />

5. Keller E, Tomecki K. Cutaneous infections and<br />

infestations: new therapies. J Clin Aesthet Dermatol.<br />

2011;4(12):18-24.<br />

6. Meinking TL, et al. Comparative in vitro pediculicidal<br />

efficacy of treatments in a resistant head<br />

lice population in the United States. Arch Dermatol.<br />

2002;138:220-224.<br />

7. Meinking TL, et al. A randomized, investigatorblinded,<br />

time-ranging study of the comparative efficacy<br />

of 0.5% malathion gel versus Ovide Lotion (0.5%<br />

malathion) or Nix Crème Rinse (1% permethrin)<br />

used as labeled, <strong>for</strong> the treatment of head lice. Pediatr<br />

Dermatol. 2007;24(4):405-411.<br />

8. Meinking TL, et al. The clinical trials supporting<br />

benzyl alcohol lotion 5% (Ulesfia): a safe and effective<br />

topical treatment <strong>for</strong> head lice (pediculosis humanus<br />

capitis). Pediatr Dermatol. 2010;27(1);19-24.<br />

9. Sanofi. Sklice Lotion prescribing in<strong>for</strong>mation.<br />

http://products.sanofi.us/Sklice/Sklice.pdf<br />

14 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


CME/CE: Neurology<br />

Concussion Care<br />

Considerations <strong>for</strong> primary care providers<br />

By Karen Williams MSN, CRNP<br />

Learning Objectives<br />

1. Identify the prevalence and mechanisms of injury involved in concussion.<br />

2. Summarize the importance of early detection, avoidance of additional concussions and<br />

early education.<br />

3. Describe how to screen <strong>for</strong> a concussion and the common presenting symptoms.<br />

4. Discuss the treatments <strong>for</strong> common symptoms of concussion.<br />

Eligibility: This article is eligible <strong>for</strong> 1 AMA PRA Category 1 Credit hour and 2 CE contact hours. After reading<br />

and completing the posttest and evaluation, eligibility <strong>for</strong> AMA PRA Category 1 Credit is available <strong>for</strong> 6 months<br />

past the publication date of this issue (Aug. 1, 2012). This article was last reviewed on July 20, 2012. The article<br />

is eligible <strong>for</strong> CE contact hours <strong>for</strong> 2 years after the publication date. The author has completed a disclosure<br />

statement and reports no relationships related to this article. The editor and reviewers have completed<br />

disclosure statements and report no relationships related to this article.<br />

This activity has been planned and implemented in accordance with the Essential Areas and policies of the<br />

Accreditation Council <strong>for</strong> Continuing Medical Education through the joint sponsorship of Wayne State University<br />

School of Medicine and <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong>. The Wayne State University School of Medicine is accredited<br />

by the ACCME to provide continuing medical education <strong>for</strong> physicians. The Wayne State University School of<br />

Medicine designates this journal-based CME activity <strong>for</strong> a maximum of 1 AMA PRA Category 1 Credit(s).<br />

Physicians should only claim the credit commensurate with the extent of their participation in the activity.<br />

This activity also is approved <strong>for</strong> 2 CE contact hours. The issuer of CE contact hours is Merion Publications (a<br />

division of Merion Matters), which is approved as a provider of continuing education in nursing by three agencies.<br />

For details on CE provider numbers, visit the CE Test Center on our website, www.advanceweb.com/NPPA.<br />

➼ Traumatic brain injury (TBI)<br />

encompasses a broad spectrum of injury<br />

with symptoms and effects that range<br />

from mild to severe.<br />

This article focuses on mild TBI (mTBI)<br />

and reviews the symptoms and treatments<br />

<strong>for</strong> this injury, commonly known<br />

as a concussion.<br />

Prevalence<br />

Head injury is a leading cause of disability<br />

throughout the world. Each year<br />

in the United States, an estimated 1.7<br />

million people sustain a TBI. 1 Concussion<br />

accounts <strong>for</strong> about 75% of these brain<br />

injuries. 2 The leading cause of TBI is<br />

falls (35.2%), followed by motor vehicle<br />

crashes (17.3%), being struck by or falling<br />

against something (16.5%), and assaults<br />

(10%). 1 In the United States armed <strong>for</strong>ces,<br />

233,425 TBIs were reported between 2000<br />

and 2011. 3 Of these, approximately 76%<br />

were mTBIs. 3<br />

➤<br />

Karen Williams is a family nurse practitioner<br />

who practices in the neurology and<br />

traumatic brain injury unit at Landstuhl Regional<br />

Medical Center in Landstuhl, Germany. She is<br />

an employee of the United States Army.<br />

Tom Whalen<br />

<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

15


CME/CE: Neurology<br />

Table 1<br />

Definition of Mild Traumatic Brain Injury 7<br />

A patient with mild traumatic brain injury has experienced a traumatically induced physiologic disruption of brain function, as<br />

manifested by at least one of the following:<br />

1. Any loss of consciousness<br />

2. Any loss of memory about events immediately be<strong>for</strong>e or after the accident<br />

3. Any alteration in mental state at the time of the accident (feeling dazed, confused, seeing stars)<br />

4. Focal neurologic deficits that may or may not be transient but in which the severity of the injury does not exceed the following:<br />

loss of consciousness <strong>for</strong> 30 minutes or less; after 30 minutes, an initial Glasgow Coma Scale score of 13 to 15; posttraumatic<br />

amnesia lasting not more than 24 hours<br />

This definition includes:<br />

1. The head being struck<br />

2. The head striking an object<br />

3. The brain undergoing an acceleration/deceleration movement (i.e., whiplash) without direct external trauma to the head<br />

Developed by the American Congress of Rehabilitation Medicine, http://www.acrm.org/pdf/TBIDef_English_Oct2010.pdf<br />

Blast-related events are the leading<br />

cause of head injury in the military,<br />

followed in order by the other events<br />

mentioned above. 4 As a result of several<br />

factors, the number of concussions<br />

reported is lower than the number of<br />

actual occurrences.<br />

Many patients who experience concussion<br />

and receive medical care do not<br />

have a TBI diagnosis recorded, especially<br />

when multiple injuries are present. 5 In<br />

addition, up to 25% of patients with a<br />

concussion do not seek medical care. 6<br />

Reasons include lack of outward physical<br />

injury, symptom resolution be<strong>for</strong>e<br />

they can seek medical care, and lack of<br />

awareness that they should seek care.<br />

In 2007, the Department of Defense<br />

(DoD) started TBI screening programs<br />

<strong>for</strong> service members who returned from<br />

war zones, in order to identify soldiers<br />

who may have sustained a concussive<br />

event while deployed. Today, screening<br />

is per<strong>for</strong>med on all service members at<br />

the end of deployment or when evacuated<br />

from theater due to injury. Because<br />

so many service members and <strong>for</strong>mer<br />

service members are seen outside the<br />

military healthcare system, providers<br />

in civilian settings should be aware of<br />

the incidence and causes of concussion<br />

in this population.<br />

Mechanisms of Injury<br />

The mechanisms of injury in an mTBI<br />

encompass one or more of the following:<br />

• Direct contact, such as something<br />

hitting the head while the head is at rest,<br />

causing focal damage.<br />

• Acceleration in combination with<br />

deceleration, also known as coup–contrecoup,<br />

in which the brain moves within<br />

the skull. This can cause damage to multiple<br />

areas, depending on how the brain<br />

slides. This can occur in a car accident<br />

that produces a <strong>for</strong>ward and backward<br />

motion of the head, causing the brain<br />

to slide. The frontal and occipital lobes<br />

absorb this impact.<br />

• Rotational <strong>for</strong>ces that cause shearing<br />

of the cerebral white matter axons.<br />

• A blast overpressure wave, followed<br />

by possible further concussive <strong>for</strong>ces, such<br />

as being hit by debris, being thrown or<br />

inhaling fumes.<br />

Diagnostic Criteria<br />

The American Congress of Rehabilitation<br />

Medicine established criteria <strong>for</strong> mTBI 7<br />

(Table 1) in 1993, defining it as a traumatically<br />

induced physiologic disruption of<br />

brain function. The diagnosis of mTBI<br />

does not mean the symptoms are mild;<br />

at times these symptoms can be disabling.<br />

In 1997, the American Academy of<br />

Neurology published a sports concussion<br />

grading system (Table 2). 8<br />

An essential common element in the<br />

two sets of criteria is a traumatic blow or<br />

jolt to the head that causes an inability<br />

<strong>for</strong> the brain to function normally, even<br />

if it is <strong>for</strong> seconds.<br />

In our current state of heightened<br />

awareness of TBI, especially among<br />

military personnel, it is not uncommon<br />

<strong>for</strong> providers and patients to diagnose a<br />

concussion based on symptoms alone.<br />

But if alteration of consciousness (AOC)<br />

or greater has not occurred, a concussion<br />

diagnosis is not appropriate. In addition<br />

to being inaccurate, a symptom-based<br />

diagnosis may delay treatment of the<br />

real diagnosis.<br />

The natural history of a concussion<br />

involves resolution within minutes to<br />

several months. 9-11 In patients older than<br />

40 and in patients with preexisting conditions,<br />

recovery may take longer. 10 When<br />

symptoms last more than 3 months, the<br />

diagnosis of post-concussion syndrome<br />

may apply.<br />

The percentage of patients who have<br />

unrelenting symptoms ranges from 5%<br />

to 15%. 12,13 Influencing factors include<br />

pre-existing conditions, psychiatric conditions,<br />

chronic pain, substance abuse,<br />

secondary gain, unemployment and lack<br />

of support systems. 14<br />

Repetitive Injury<br />

Education about the prevention of repeat<br />

brain injury is vital yet often overlooked.<br />

A patient with a concussion may not be<br />

thinking clearly and may put himself or<br />

herself at risk <strong>for</strong> additional head injuries.<br />

In addition, the patient’s reaction time<br />

may be slowed.<br />

Several studies have documented the<br />

consequences of repeat concussions.<br />

Repetitive brain injury can lead to longer<br />

lasting symptoms, chronic headaches,<br />

slower response time and decreased academic<br />

scores. 15<br />

Recent studies of football players who<br />

sustained multiple concussions identified<br />

changes to brain pathology, known<br />

as chronic traumatic encephalopathy, 16<br />

16 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


CME/CE: Neurology<br />

which may increase the risk of neurologic<br />

disorders such as Alzheimer and<br />

Parkinson diseases. 17<br />

Diagnosis of Concussion<br />

Until an objective measure is available,<br />

the only way to diagnose a concussion<br />

is through a history of the event. It is<br />

best to use an open-ended <strong>for</strong>mat to<br />

interview the patient and/or others who<br />

witnessed the injury. Let them tell their<br />

story and describe what they were doing<br />

just be<strong>for</strong>e, during and afterward. Ask<br />

the patient to include what he or she saw,<br />

heard, smelled, tasted and felt. In some<br />

cases, it may not be possible to establish<br />

whether loss of consciousness (LOC) or<br />

post-traumatic amnesia (PTA) occurred.<br />

Establish the timeline of the event<br />

as soon as possible, when memories<br />

are fresher. In addition to helping with<br />

questions about the case later on, recording<br />

early memories helps confirm the<br />

length and degree of cognitive impairment.<br />

Understanding the particulars of the<br />

injury is helpful: type of vehicle, belted or<br />

not, protective gear, position, speed, what<br />

body part hit what, and so on. Ask whether<br />

any damage to protective gear occurred<br />

(crack in helmet or safety glasses, etc).<br />

What symptoms did the patient experience<br />

right after the event, and what are the<br />

current symptoms Common symptoms<br />

immediately after a concussive event can<br />

include headache, tinnitus, dizziness,<br />

nausea, vomiting and increased irritability.<br />

The initial interview should also<br />

include a thorough patient history to<br />

evaluate concurrent conditions, current<br />

or prior use of alcohol or drugs, current<br />

medications, caffeine use, dietary<br />

habits and prior history of concussions.<br />

These answers are helpful in determining<br />

treatment options and in identifying<br />

issues that may exacerbate symptoms or<br />

complicate recovery. 11<br />

The physical examination portion of<br />

the visit should consist of three parts:<br />

• a focused neurologic exam including<br />

a mental status assessment, cranial<br />

nerve testing, extremity tone and deep<br />

tendon reflex testing, strength, sensation,<br />

gait and postural stability (Romberg test)<br />

• a focused vision exam including<br />

gross acuity, eye movement, binocular<br />

function and visual fields/attention<br />

Table 2<br />

Sports Concussion Grading System 8<br />

Grade 1: Transient confusion with resolution of symptoms in less than 15 minutes<br />

Grade 2: Transient confusion and symptoms lasting more than 15 minutes<br />

Grade 3: Any loss of consciousness<br />

Developed by the American Academy of Neurology, http://www.aan.com/professionals/practice/guidelines/<br />

pda/Concussion_sports.pdf<br />

Table 3<br />

Indications <strong>for</strong> Computed Tomography After<br />

Minor Head Injury 18<br />

(The New Orleans Criteria)<br />

Consider computed tomography within 7 days of minor traumatic brain injury <strong>for</strong><br />

patients who exhibit one or more of the following:<br />

◗ Physical evidence of trauma above the clavicles<br />

◗ Seizure<br />

◗ Vomiting<br />

◗ Headache<br />

◗ Short-term memory deficits (persistent antrograde amnesia)<br />

◗ Age older than 60<br />

◗ Drug or alcohol intoxication at the time of injury<br />

◗ Coagulopathy<br />

http://www.nejm.org/doi/pdf/10.1056/NEJM200007133430204<br />

• a focused musculoskeletal examination<br />

of the head and neck, to include<br />

range of motion of the neck and jaw, focal<br />

tenderness and referred pain.<br />

Normal neurologic exam findings suggest<br />

that no major structural injuries to<br />

the brain have occurred. Findings that<br />

require urgent consultation with the<br />

neurology or neurosurgery departments<br />

include altered consciousness, progressive<br />

decline in neurologic findings, pupillary<br />

asymmetry, seizures, repeated vomiting,<br />

double vision, worsening headache,<br />

inability to recognize people, disorientation<br />

to place, unusual behavior, confusion,<br />

slurred speech, unsteadiness, and<br />

weakness or numbness of arms or legs. 11<br />

Understanding the mechanism of injury<br />

helps determine whether radiologic<br />

studies are needed. The New Orleans<br />

criteria <strong>for</strong> computed tomography after<br />

minor head injury are shown in Table 3<br />

and are intended <strong>for</strong> use within the first<br />

7 days after injury. 18 If imaging is desired<br />

after the first 7 days, it may be more effective<br />

to use MRI or other imaging studies<br />

that can provide more detail about the<br />

brain anatomy.<br />

Often, an affected patient exhibits<br />

no outward signs of a concussion. The<br />

symptoms of concussion are wide ranging.<br />

Physical symptoms of concussion<br />

include headache, dizziness, balance<br />

problems, nausea or vomiting, fatigue,<br />

visual disturbances, light sensitivity, tinnitus,<br />

and sleep disturbances. Cognitive<br />

symptoms include slowed thinking, poor<br />

concentration, trouble with word choice,<br />

and short-term memory loss. Emotional<br />

issues include anxiety, depression, irritability<br />

and mood swings.<br />

The physical examination findings and<br />

the symptom complaints should direct<br />

care. Start with the symptom that is most<br />

disabling <strong>for</strong> the patient. An interplay may<br />

exist among some of the most common<br />

symptoms. When one of the symptoms<br />

is treated effectively, others may improve.<br />

For example, the symptoms of headache,<br />

sleep disturbance, memory loss and mood<br />

change tend to improve when one of them<br />

is improved. 19<br />

➤<br />

<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

17


CME/CE: Neurology<br />

The most effective treatment approach is thorough patient education about<br />

concussion, the patient's particular findings, possible treatments and the<br />

expectation <strong>for</strong> recovery.<br />

Tools are available to assess symptoms<br />

after a concussion. The Rivermead Post-<br />

Concussion Symptom Inventory is a validated<br />

tool that can be used to track the<br />

course of symptoms, including impact<br />

on the patient and his or her daily functioning<br />

(http://www.tbi-impact.org/cde/<br />

mod_templates/12_F_06_Rivermead.pdf). 20<br />

Treatments<br />

The most effective treatment approach<br />

is thorough patient education about concussion,<br />

the patient’s particular findings,<br />

possible treatments and the expectation<br />

<strong>for</strong> recovery. 21 This education should be<br />

repeated at subsequent visits, due to the<br />

short-term memory issues and anxiety<br />

common in this population.<br />

Typical areas to cover in patient education<br />

include the natural history of mTBI<br />

and expected recovery, sleep hygiene techniques,<br />

the need <strong>for</strong> abstinence from drugs<br />

and alcohol (which can increase symptoms<br />

and decrease the brain’s ability to heal),<br />

proper nutrition, coping strategies and<br />

avoidance of repeat concussion. The dangers<br />

of self-medication should be addressed,<br />

since patients may try caffeinated beverages<br />

to treat cognitive issues, alcohol or drugs<br />

to help with sleep and anxiety, and OTC<br />

medications to treat headaches or other<br />

symptoms. Rein<strong>for</strong>ce the need <strong>for</strong> rest and<br />

Table 4<br />

Additional Resources<br />

avoidance of caffeine and alcohol, as well<br />

as use of medications only as prescribed.<br />

Using a medication organizer is one way<br />

of ensuring the patient safely dispenses his<br />

or her own medication in the right dosing<br />

and time frame.<br />

Until the patient has recovered, he or<br />

she should not engage in activities that<br />

will increase symptoms, such as mental<br />

or physical exertion. Depending on home<br />

and work status, specific guidance about<br />

return to work or school may be necessary.<br />

Start with a gradual increase in activity<br />

and increase the amount of activity as<br />

symptoms improve. 11 Driving, climbing<br />

and operating heavy machinery are areas<br />

of concern when visual, balance, cognitive<br />

or coordination difficulties exist.<br />

Cognitive functioning should return<br />

to baseline about 7 days to 1 month after<br />

mTBI. 21 Instruct the patient to follow up<br />

in 1 week if symptoms are not improving.<br />

Make a specialist referral <strong>for</strong> evaluation<br />

of ongoing cognitive symptoms or other<br />

symptoms that are severe, such as depression,<br />

pain or post-traumatic stress. 22,23<br />

These specialists may use neuropsychologic<br />

testing to help determine when return<br />

to work, school or play is appropriate. 24<br />

The involvement of several medical and<br />

complementary specialties may be necessary<br />

to provide complete care. Depending<br />

The Centers <strong>for</strong> Disease Control and Prevention operates a concussion resource<br />

center at http://www.cdc.gov/Concussion/.<br />

The Defense and Veterans Brain Injury Center website, www.DVBIC.org, provides<br />

in<strong>for</strong>mation <strong>for</strong> service members and their families, as well as <strong>for</strong> healthcare providers.<br />

At this site, you can request a copy of the “Mild Traumatic Brain Injury Pocket Guide”<br />

and other tools. These can also be downloaded to iPhones, iPads and devices that use<br />

the Android plat<strong>for</strong>m.<br />

The Veterans Administration and Department of Defense clinical practice guideline <strong>for</strong><br />

the management of mild traumatic brain injury is geared toward healthcare providers<br />

within the VA/DoD healthcare setting, but it can be useful to providers in the civilian<br />

setting. http://www.dvbic.org/pdf/VADoD-CPG---Concussion-mTBI.pdf<br />

The American Association of Neuroscience Nurses and the Association of Rehabilitation Nurses developed<br />

“Care of the Patient with Mild Traumatic Brain Injury.” This document can be downloaded at http://www.<br />

rehabnurse.org/uploads/files/cpgmtbi.pdf<br />

on the provider’s level of com<strong>for</strong>t and the<br />

resources in the clinic, several symptoms<br />

may be appropriate <strong>for</strong> treatment in primary<br />

care. Adopt a “start low and go slow”<br />

approach to any prescription medications.<br />

After injury, the brain is more sensitive<br />

to medication and there<strong>for</strong>e the risk of<br />

side effects increases. 25<br />

Headaches are often managed by primary<br />

care providers, and in this patient<br />

population headache would be a typical<br />

symptom to treat. The cause of post-traumatic<br />

headache is not completely understood,<br />

but the treatments are aimed at the<br />

type of headache that occurs: migrainous,<br />

tension-type, cervicogenic, overuse/<br />

rebound, chronic daily or combination.<br />

Treatments <strong>for</strong> these headaches include<br />

non-narcotic pain medications (avoiding<br />

tramadol because it can increase seizure<br />

risk), nonsteroidal anti-inflammatory<br />

drugs, triptans, tricyclic antidepressants,<br />

anti-epileptic drugs, beta-blockers, botulinum<br />

toxin and occipital blocks. Referral to<br />

a neurologist may be beneficial depending<br />

on the experience of the clinician, the type<br />

of headaches experienced and the response<br />

to attempted treatments. Refer to a dentist<br />

<strong>for</strong> evaluation of pain, popping or clicking<br />

at the temporomandibular joint.<br />

Sleep problems are common in patients<br />

who have experienced a concussion. They<br />

may report trouble getting to sleep, frequent<br />

awakenings, nightmares or weird<br />

dreams. Good sleep hygiene and the<br />

incorporation of relaxation techniques<br />

can be helpful. Trazodone is considered<br />

first-line treatment <strong>for</strong> sleep disturbances<br />

in patients recovering from concussion;<br />

this is an off-label use. 26 The short-term<br />

use of sleep aids such as zolpidem or<br />

eszopiclone can provide quick results<br />

<strong>for</strong> patients. Other possibilities are using<br />

medications that will work on multiple<br />

issues, such as a tricyclic antidepressant<br />

that helps prevent headaches, increases<br />

nighttime sleepiness and may improve<br />

mood. It is important to avoid the use<br />

of benzodiazepines because they may<br />

interfere with neuronal recovery. 27 Referral<br />

18 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


CME/CE: Neurology<br />

to a behavioral health provider may be<br />

helpful <strong>for</strong> cognitive behavioral therapy<br />

and to rein<strong>for</strong>ce sleep hygiene techniques.<br />

Balance and vision are two areas that<br />

require additional questions in order to<br />

clarify the true problem. Three systems<br />

maintain balance: the functional nervous<br />

system, the visual system and the vestibular<br />

system. Concussion may cause issues<br />

with vision and/or the vestibular system.<br />

Balance issues may present in a variety<br />

of ways. Many patients complain of “dizziness,”<br />

and clinicians must differentiate what<br />

type of balance difficulties or sensations<br />

they are experiencing. Vertigo causes a<br />

spinning sensation, usually when changing<br />

head position quickly. Benign paroxysmal<br />

positional vertigo is common in association<br />

with concussion and can be treated<br />

by per<strong>for</strong>ming a procedure to reposition<br />

the crystals in the semicircular canals of<br />

the inner ear. This is often per<strong>for</strong>med by a<br />

specialist with training in vestibular rehabilitation.<br />

These specialists may include<br />

physical therapists, audiologists or occupational<br />

therapists. Some patients describe<br />

a feeling of rocking on a boat, which can<br />

be indicative of visual disturbances and/or<br />

a milder vestibular issue. In this case, the<br />

patient may require the services of both<br />

vestibular and optometry specialists. Still<br />

others may have occasional lightheadedness<br />

when standing quickly.<br />

Visual problems that may occur after<br />

concussion include photosensitivity,<br />

difficulty maintaining reading focus<br />

(convergence), difficulty with distance<br />

perception (accommodation) and, on<br />

occasion, double vision in one or more<br />

areas of gaze. The patient may or may<br />

not mention these problems, so ask about<br />

vision changes. Regardless of findings,<br />

any patient who reports vision changes<br />

should receive a referral to optometry<br />

or ophthalmology <strong>for</strong> evaluation with<br />

binocular examination. This examination<br />

can identify difficulties with maintaining<br />

focus. Treatments include eye exercises to<br />

strengthen the ocular nerves and muscles<br />

and possibly a prescription <strong>for</strong> glasses.<br />

Additional specialties that may be<br />

of benefit, depending on the patient’s<br />

symptoms, are:<br />

• Neurology <strong>for</strong> management of headaches,<br />

sleep and pain<br />

• Behavioral health professionals <strong>for</strong><br />

mood, sleep and pain management, cognitive<br />

testing and related treatment<br />

• Social work and nurse case management<br />

<strong>for</strong> biopsychosocial evaluation,<br />

education and support based upon this<br />

evaluation<br />

• Speech therapy <strong>for</strong> evaluation of<br />

speech and language skills, from a foundational<br />

framework<br />

• Occupational therapy <strong>for</strong> evaluation<br />

of cognitive assessment, from a functional<br />

standpoint<br />

• Audiology <strong>for</strong> evaluation of tinnitus,<br />

vestibular function and auditory processing<br />

• Physical therapy <strong>for</strong> evaluation and<br />

treatment of balance, gait and vestibular<br />

management<br />

• Optometry <strong>for</strong> evaluation of visual<br />

acuity and binocular testing.<br />

Get Connected<br />

Concussions are common and can be a<br />

challenge to treat. The best preparation<br />

is to become familiar with concussion<br />

resources in your area and to equip yourself<br />

with basic knowledge about how to<br />

assess, diagnose and treat mTBI. Table<br />

4 lists resources that can provide further<br />

guidance. ■<br />

References<br />

1. Faul M, et al. Traumatic brain injury in the United<br />

States: emergency department visits, hospitalizations,<br />

and deaths: 2002-2006. http://www.cdc.gov/traumaticbraininjury/pdf/blue_book.pdf.<br />

2. Centers <strong>for</strong> Disease Control and Prevention,<br />

National Center <strong>for</strong> Injury Prevention and Control.<br />

Report to Congress on mild traumatic brain injury<br />

in the United States: steps to prevent a serious public<br />

health problem. http://www.cdc.gov/ncipc/pub-res/<br />

mtbi/mtbireport.pdf.<br />

3. Armed Forces Health Surveillance Center,<br />

2012. TBI numbers by severity. www.dvbic.org/TBI-<br />

Numbers.aspx.<br />

4. Champion HR, et al. Injuries from explosions:<br />

physics, biophysics, pathology, and required researchfocus.<br />

J Trauma. 2009;66(5):1468-1477.<br />

5. Moss NE, et al. Admissions after head injury:<br />

how many occur and how many are recorded Injury.<br />

1996;27(3):159-161.<br />

6. Sosin DM, et al. The incidence of mild and moderate<br />

brain injury in the United States 1991. Brain Inj.<br />

1996;10(1)47-54.<br />

7. American Congress of Rehabilitation Medicine.<br />

Definition of mild traumatic brain injury. J Head<br />

Trauma Rehabil. 1993;8(3):86-87. http://www.acrm.<br />

org/pdf/TBIDef_English_Oct2010.pdf.<br />

8. Ruff RM, et al; NAN Policy and Planning<br />

Committee. Recommendations <strong>for</strong> diagnosing a<br />

mild traumatic brain injury: a National Academy<br />

of Neuropsychology education paper. Arch Clin<br />

Neuropsychol. 2009;24(1):3-10.<br />

9. Levin HS, et al. Neurobehavioral outcome following<br />

minor head injury: a three-center study. J<br />

Neurosurg. 1987;66(2):234-243.<br />

10. McCrea MA. Acute Symptoms and Symptom<br />

Recovery. In: Mild Traumatic Brain Injury and<br />

Postconcussion Syndrome: The New Evidence Base<br />

<strong>for</strong> Diagnosis and Treatment. New York: Ox<strong>for</strong>d<br />

University Publishing Press; 2008: 86.<br />

11. Hoge CW, et al. Mild traumatic brain injury<br />

in U.S. soldiers returning from Iraq. N Engl J Med.<br />

2008;358(5):453-463.<br />

12. Alexander MP. Mild traumatic brain injury:<br />

pathophysiology, natural history, and clinical management.<br />

Neurology. 1995;45(7):1253-1260.<br />

13. Ruff RM, et al. Miserable minority: emotional risk<br />

factors that influence the outcome of a mild traumatic<br />

brain injury. Brain Inj. 1996;10(8):551-565.<br />

14. Department of Veterans Affairs & Department<br />

of Defense. Clinical Practice Guideline. Management<br />

of Concussion/Mild Traumatic Brain Injury. http://<br />

www.healthquality.va.gov/mtbi/concussion_mtbi_<br />

full_1_0.pdf.<br />

15. Guskiewicz KM, et al. Cumulative effects associated<br />

with recurrent concussion in collegiate football<br />

players: the NCAA concussion study. JAMA.<br />

2003;290(19):2549-2555.<br />

16. McKee AC, et al. Chronic traumatic encephalopathy<br />

in athletes: progressive tauopathy after<br />

repetitive head injury. J Neuropathol Exp Neurol.<br />

2009;68(7):709-735.<br />

17. National Institute of Neurological Disorders and<br />

Stroke. Traumatic brain injury: hope through research.<br />

Bethesda, MD: National Institutes of Health; 2002.<br />

NIH Publication No.: 02-158. http://www.ninds.nih.<br />

gov/disorders/tbi/detail_tbi.htm.<br />

18. Haydel MJ, et al. Indications <strong>for</strong> computed tomography<br />

in patients with a minor head injury. New Engl<br />

J Med. 2000;343(2):100-105.<br />

19. Oullet MC, Morin CM. Efficacy of cognitivebehavioral<br />

therapy <strong>for</strong> insomnia associated with<br />

traumatic brain injury: a single-case experimental<br />

design. Arch Phys Med Rehab. 2007;88(12):1581–1592.<br />

20. King NS, et al. The Rivermead Post Concussion<br />

Questionnaire: A measure of symptoms commonly<br />

experienced after head injury and its reliability. J<br />

Neurol. 1995;242(9):587-592.<br />

21. Pons<strong>for</strong>d J, et al. Impact of early intervention on<br />

outcome following mild head injury in adults. J Neurol<br />

Neurosurg Psychiatry. 2002;73(3):330-332.<br />

22. Frenchman KA, et al. Neuropsychological studies<br />

of mild traumatic brain injury: a meta-analytic<br />

review of research since 1995. J Clin Exp Neuropsychol.<br />

2005;27(3):334-351.<br />

23. Gioia G, et al. New approaches to assessment<br />

and monitoring of concussion in children. Topics in<br />

Language Disorders. 2009;29(3):266-281.<br />

24. Jagoda AS, et al. Clinical policy: neuroimaging and<br />

decision making in adult mild traumatic brain injury in<br />

the acute setting. Ann Emerg Med. 2008;52(6):714-748.<br />

25. Cifu D, et al. Repetitive head injury syndrome.<br />

http://emedicine.medscape.com/article/92189-overview.<br />

26. Arciniegas DB, et al. Mild traumatic brain injury: a<br />

neuropsychiatric approach to diagnosis, evaluation, and<br />

treatment. Neuropsychiatr Dis Treat. 2005;1(4):311-327.<br />

27. Zasler ND. Advances in neuropharmacological<br />

rehabilitation <strong>for</strong> brain dysfunction. Brain Inj.<br />

1992;6(1):1-14.<br />

Better Mental Healthcare <strong>for</strong> Veterans<br />

➼ Enter "healthcare <strong>for</strong> veterans" in the Search<br />

Articles box at www.advanceweb.com/NPPA to find "Improving<br />

Healthcare <strong>for</strong> Veterans and Military Families" and hear how<br />

healthcare organizations have partnered with a White House<br />

initiative called Joining Forces to increase access to mental<br />

healthcare <strong>for</strong> the military.<br />

<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

19


CME/CE: Neurology<br />

Concussion • NPPA24<br />

Questions<br />

1. The leading cause of concussion<br />

in the U.S. civilian population is:<br />

a. Assaults<br />

b. Falls<br />

c. Motor vehicles accidents<br />

d. Being struck by something<br />

2. Reasons <strong>for</strong> not receiving care<br />

after a concussion include which of<br />

the following<br />

a. Multiple injuries have occurred<br />

b. Lack of outward physical signs<br />

c. Unaware of the need to seek care<br />

d. All the above<br />

3. Mechanism of injury in mild TBI<br />

includes:<br />

a. Cerebral vascular accident<br />

b. Acceleration/deceleration in a<br />

rapid and <strong>for</strong>ceful way<br />

c. Blast overpressure wave<br />

d. Both B & C<br />

4. Which statement is most<br />

accurate in describing diagnostic<br />

criteria <strong>for</strong> a concussion<br />

a. You can diagnose a concussion<br />

based on the symptoms.<br />

b. A loss of consciousness must<br />

accompany a blow or jolt to the<br />

head.<br />

c. A blow or jolt to the head<br />

that causes any alteration of<br />

consciousness.<br />

d. None of the above<br />

5. Why is education to prevent a<br />

repeat head injury important<br />

a. The postconcussive patient may<br />

have slowed reaction time.<br />

b. Repetitive injury may lead to<br />

longer lasting symptoms.<br />

c. Multiple concussions may lead to<br />

changes in brain pathology.<br />

d. All of the above<br />

6. Diagnosis of concussion is made<br />

using which of the following<br />

a. History of the event<br />

b. Brain imaging<br />

c. Focused neurologic exam<br />

d. Evaluation by biomarkers<br />

7. Appropriate examination of the<br />

patient who has had a concussion<br />

includes:<br />

a. A focused neurologic exam<br />

b. Focused vision exam<br />

c. CT of the head<br />

d. Both A & B<br />

8. The most effective treatment <strong>for</strong><br />

a concussion is:<br />

a. Patient education about expected<br />

recovery<br />

b. Management of headache<br />

c. Management of sleep disorders<br />

d. Management of memory issues<br />

9. When prescribing medication<br />

to a postconcussive patient, the<br />

following applies:<br />

a. It is important to start low and<br />

go slow.<br />

b. The patient will not require<br />

medication.<br />

c. Medications should be started at<br />

the highest possible dosing.<br />

d. Start with multiple medications<br />

at one time.<br />

10. The following specialists may<br />

be considered when caring <strong>for</strong> the<br />

postconcussive patient:<br />

a. Optometry<br />

b. Neurology<br />

c. Occupational therapy<br />

d. All the above<br />

Evaluation<br />

1. The educational objectives were<br />

achieved.<br />

a. strongly disagree<br />

b. disagree<br />

c. neutral<br />

d. agree<br />

e. strongly agree<br />

2. Based on what you learned in<br />

this article, will you make changes<br />

in your practice<br />

a. yes<br />

b. no<br />

If yes, please describe the changes<br />

you intend to make: _____________<br />

_______________________________<br />

What barriers to change do you<br />

anticipate ______________________<br />

_______________________________<br />

What strategies or mechanisms will<br />

you apply to overcome these barriers<br />

_______________________________<br />

_______________________________<br />

3. The in<strong>for</strong>mation in the article<br />

was fair, balanced, free of<br />

commercial bias and supported by<br />

scientific evidence.<br />

a. yes<br />

b. no<br />

If no, describe the nature of the issue:<br />

_______________________________<br />

Registration & Answer Form<br />

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To obtain CME credit, send the completed answer <strong>for</strong>m and registrant in<strong>for</strong>mation<br />

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Concussion August 2012<br />

Test NPPA24<br />

Evaluation<br />

A B C D A B C D A B C D E<br />

1.<br />

2.<br />

3.<br />

4.<br />

5.<br />

6.<br />

7.<br />

8.<br />

9.<br />

10.<br />

1.<br />

2.<br />

3.<br />

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20 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


Gastroenterology<br />

Beware the<br />

Irritable Bowel<br />

Deciphering the overlap of symptoms<br />

By Susan Andersen, PhD, RN, FNP-BC<br />

➼ As Sharon sat in the lobby waiting<br />

to be called <strong>for</strong> her annual exam, she<br />

realized she was checking off questionnaire<br />

answers in nearly every body system.<br />

Headaches, diarrhea, constipation,<br />

bloating, flatulence, abdominal pain and<br />

cramping, frequent mouth sores, fatigue,<br />

depression, an itchy rash that would not<br />

go away … How long had she felt this<br />

way She couldn’t remember. “Just how<br />

sick am I” she wondered.<br />

This is a typical scenario <strong>for</strong> a patient<br />

presenting with a functional bowel disorder,<br />

which despite its symptomatic<br />

nature has no identifiable mechanical<br />

cause. Functional bowel disorders include<br />

irritable bowel syndrome (IBS), functional<br />

diarrhea and chronic constipation.<br />

Celiac disease and gluten sensitivity<br />

cause symptoms similar to those of IBS,<br />

but these are not considered functional<br />

bowel disorders.<br />

The fact that 33% to 90% of people<br />

who experience IBS symptoms do not<br />

consult a healthcare provider contributes<br />

to the variability in prevalence estimates. 2<br />

Most IBS patients in Western countries<br />

are never diagnosed, with the exception<br />

of the United Kingdom and Italy, where<br />

about half of positive cases are identified.<br />

Predictors of healthcare-seeking include<br />

severity of abdominal pain and distention,<br />

Rome criteria status (http://romecriteria.<br />

org/assets/pdf/19_RomeIII_apA_885-898.<br />

pdf) and impact on mood and lifestyle.<br />

Studies show that patients experience<br />

symptoms between 5 and 13 years prior<br />

to diagnosis. Although comorbidity with<br />

other GI disorders or mortality is not<br />

associated with IBS, no cure has been<br />

identified. One review found the mean<br />

direct costs of IBS management to be<br />

$619 per patient annually, with total direct<br />

costs of $1.35 billion. 6 Productivity losses<br />

in the United States range from $335 to<br />

$748 per patient, <strong>for</strong> an annual total of<br />

$205 million due to lost workdays. Costs<br />

to patients with celiac disease were $4,000<br />

(all patients) to $10,000 (men) higher<br />

annually than <strong>for</strong> healthy controls. 7 From<br />

these numbers, we can extrapolate that<br />

if 1% of the U.S. population is affected<br />

by IBS, the annual healthcare costs are<br />

$124.4 million to $311 million.<br />

IBS negatively affects quality of life and<br />

social function. Patients may experience<br />

increased anxiety, depression, pain and<br />

discom<strong>for</strong>t. 8 Patients in whom constipation<br />

predominates among IBS symptoms<br />

have significantly lower quality-of-life<br />

scores on physical and mental components<br />

Epidemiology<br />

IBS is diagnosed in 1 in 5 Americans<br />

each year. 1 Among adults, IBS incidence<br />

peaks between ages 30 and 50. 2 Women<br />

are affected twice as often as men at<br />

younger ages, but men and women are<br />

at equal risk later in life. 2 The estimated<br />

prevalence of IBS in Western countries<br />

varies widely, from 5% to 15%. 3-5 Italy has<br />

the highest prevalence among developed<br />

countries. 3-5<br />

tom whalen<br />

Susan Anderson is a family nurse practitioner<br />

who is an associate professor in the<br />

School of Nursing at Texas Tech University<br />

Health Sciences Center in Lubbock, Texas.<br />

She has completed a disclosure statement and<br />

reports no relationships related to this article.<br />

<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

21


Gastroenterology<br />

Table 1<br />

Common and Red Flag Differential Diagnoses <strong>for</strong> IBS<br />

Disorder Signs & Symptoms Diagnostic Tests<br />

Ulcerative colitis Peaks ages 15 to 35<br />

Sigmoidoscopy, colonoscopy, barium enema<br />

Bloody diarrhea with mucus, fever, abdominal pain,<br />

tenesmus, weight loss<br />

Crohn’s disease Onset ages 15 to 35 or 70 to 80<br />

Sigmoidoscopy, colonoscopy, barium enema<br />

Fever, abdominal pain, diarrhea, fatigue, weight loss<br />

Anorectal fissures, fistulae, abscesses<br />

Infectious diarrhea Chronic diarrhea with cramps with or without blood Microscopy, stool studies, sigmoidoscopy<br />

and mucus<br />

Diverticulitis Lower left abdominal pain, fever, altered bowel habits Complete blood count, computed tomography, barium<br />

enema<br />

Colorectal<br />

malignancy<br />

Age 50 or older<br />

Rectal bleeding, altered bowel habits, abdominal or<br />

back pain, anemia, occult blood in stool, weight loss<br />

Colonoscopy<br />

Medication side<br />

effects<br />

Antacids, laxatives, selective serotonin reuptake<br />

inhibitors, thyroid hormones, met<strong>for</strong>min, narcotics,<br />

calcium-channel blockers, anticholinergics<br />

History of concordance of symptoms with medication<br />

initiation; trial of drug holiday or reducing dosage;<br />

rechallenge confirms<br />

and significantly more work and activity<br />

impairments than people without IBS. 9<br />

People with IBS take more time off work,<br />

resulting in significant economic effects.<br />

Chronic ongoing life stress can predict<br />

the prognosis of patients with IBS. 7<br />

Significant overlap among functional<br />

bowel disorders exists; 42% to 87% of<br />

patients with IBS also experience functional<br />

dyspepsia, with symptoms of<br />

epigastric pain, nausea, vomiting, weight<br />

loss and early satiety. 7 Most people with<br />

IBS experience functional constipation,<br />

functional diarrhea, or both. People<br />

with IBS are four times more likely to<br />

also have celiac disease. 7 There<strong>for</strong>e, it is<br />

important to maintain a high degree of<br />

suspicion about the presence of gluten<br />

sensitivity as an underlying cause of<br />

pathology.<br />

Etiology<br />

A current theory about the pathophysiologic<br />

origin of IBS is visceral hypersensitivity<br />

resulting from disturbances in<br />

gastrointestinal serotonin metabolism. 10<br />

Serotonin, released by enterochromaffin<br />

cells in the gastrointestinal mucosa, is<br />

the principal mediator of gut motility<br />

and visceral sensation. Patients with IBS<br />

also exhibit differences in central pain<br />

processing, as measured by functional<br />

brain magnetic resonance imaging.<br />

Other causes may include inflammation,<br />

intestinal permeability, food sensitivity,<br />

lack of dietary fiber and antibiotics.<br />

Genetic factors or role modeling may<br />

influence the development of IBS, since<br />

clustering within families has been documented.<br />

10,11 Psychological factors also<br />

may play a role. 10,11 IBS can develop after<br />

enteric infections, suggesting the importance<br />

of peripheral neurologic processes,<br />

with or without psychological triggers. 10,11<br />

Neuromotor dysfunction has also<br />

been investigated as a symptom trigger.<br />

Increasing evidence shows that chronic,<br />

low-grade inflammation is associated<br />

with IBS. Up to 30% of patients with<br />

a GI infection develop persistent lowgrade<br />

inflammation and IBS symptoms,<br />

prompting consideration of the role of<br />

bacterial overgrowth. 12<br />

Gluten and Lactose<br />

The role of food-related irritation in<br />

IBS symptoms is supported by numerous<br />

studies. In one of these, researchers<br />

found IgG4 antibodies to wheat in 60%<br />

Table 2<br />

Common Comorbidities 2<br />

Chronic fatigue syndrome 92%<br />

Fibromyalgia 77%<br />

Temporomandibular joint<br />

disorder<br />

64%<br />

Chronic pelvic pain 50%<br />

of patients who had IBS, compared with<br />

27% of healthy people. 12 Contributing to<br />

the confusion and lack of clarity about<br />

the causative role of food in IBS is that<br />

controlled trials often do not support<br />

this contention. 11 The ubiquity of glutencontaining<br />

foods in the Western diet<br />

makes it difficult <strong>for</strong> people with IBS<br />

symptoms to identify this as a causative<br />

agent. Other contributing factors may<br />

also be at work, such as unique physiologic<br />

and genetic characteristics that<br />

interact with food and the environment.<br />

Pathological and clinical symptoms in<br />

IBS can vary from subtle to severe due<br />

to gluten sensitivity, and this variation<br />

is not explained by mucosal damage. 13,14<br />

Patients who have gluten sensitivity simply<br />

respond positively to a diet free of<br />

gluten, which is found in wheat, barley,<br />

rye and perhaps oats. (Whether oats<br />

contain gluten is controversial. Some<br />

experts maintain that reaction to oats<br />

by some patients with gluten sensitivity<br />

is due to cross contamination during the<br />

refining process. However, some cultivars<br />

of oats may contain gluten.)<br />

Some evidence suggests that subtle<br />

immunopathologic changes may occur<br />

in the intestine when it is exposed to<br />

gluten. 16 Changes may include increased<br />

intraepithelial lymphocytosis, increased<br />

IgA deposition in the intestinal villi,<br />

changes in the microvillus border, and<br />

increased secreted antibodies directed<br />

22 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


Gastroenterology<br />

Table 3<br />

Pharmacologic Therapy<br />

Purpose When to use Class Examples Indication<br />

Pain Control<br />

First line<br />

(mild symptoms)<br />

Second line (mild to<br />

moderate symptoms)<br />

Antispasmodics<br />

Tricyclic antidepressants,<br />

SSRIs*<br />

Dicyclomine, hyoscyamine,<br />

encapsulated peppermint oil<br />

Amitriptyline, fluoxetine*<br />

Reduce spasms and pain<br />

Reduce pain and diarrhea<br />

Constipation First line Bulking agents Psyllium Restore stool motility<br />

Chloride-channel activator Lubiprostone Severe, refractory constipation<br />

Diarrhea First line Antidiarrheal Loperamide Reduce stool<br />

Second line Serotonin-3 antagonist Alosetron Severe, refractory diarrhea<br />

*few placebo controlled trials to support<br />

against gliadin, a glycoprotein found in gluten-containing<br />

cereals. Often, these disorders occur in patients carrying the<br />

same human leukocyte antigen (HLA) genotypes associated<br />

with celiac disease, DQ2 and DQ8.<br />

This immunopathology was found earliest in family members<br />

of people with celiac disease who, despite not having villous<br />

atrophy, had evidence of immune responsiveness to gluten<br />

(i.e., diarrhea after gluten ingestion). 15 This finding supports<br />

the emerging consensus that gluten sensitivity is an abnormal<br />

immune response to gluten that can occur without the intestinal<br />

damage seen in celiac disease. However, some patients who are<br />

sensitive to gluten but have negative biopsies and serology may<br />

eventually develop mucosal damage. 16 No therapeutic guidelines<br />

<strong>for</strong> gluten sensitivity have been published.<br />

Lactose intolerance also causes IBS symptoms of diarrhea,<br />

abdominal pain, flatulence and bloating. The prevalence of<br />

lactose intolerance is unknown, 17 but it affects many racial and<br />

ethnic groups in the United States. Symptoms are caused by<br />

malabsorption of lactose due to a deficiency in lactase, which<br />

is required to digest lactose. Lactase metabolizes lactose into<br />

two simpler sugars, glucose and galactose, which are readily<br />

absorbed into the bloodstream. This enzyme is produced by<br />

expression of the lactase-phlorizin hydrolase gene in the cells<br />

lining the small intestine. 17<br />

Infants normally produce lactase and digest lactose in human<br />

milk or infant <strong>for</strong>mulas. After weaning, most children are<br />

genetically programmed to produce less lactase. The symptoms<br />

of lactose intolerance are caused by bacterial fermentation of<br />

undigested lactose in the colon. 17<br />

The demonstration of lactose malabsorption does not necessarily<br />

indicate that a patient will be symptomatic. Many variables<br />

determine whether a person develops symptoms, including<br />

the amount of lactose ingested, the residual intestinal lactase<br />

activity, the ingestion of food along with lactose, the ability of<br />

the colonic flora to ferment lactose, and individual sensitivity<br />

to the products of lactose fermentation. 17<br />

Diagnosis<br />

Functional GI disorders are diagnosed clinically. IBS is a<br />

chronic, relapsing gastrointestinal syndrome diagnosed using<br />

current Rome criteria. 3 Behavioral features of IBS that can help<br />

diagnose it are: symptoms <strong>for</strong> more than 6 months; “frequent<br />

flyer” visits <strong>for</strong> non-GI symptoms; prior medically unexplained<br />

symptoms; and intensification of symptoms with stress.<br />

Red flags <strong>for</strong> more significant or life-threatening diagnoses<br />

(i.e., age older than 50, recent symptom onset, weight loss,<br />

nighttime NP010603-0008 symptoms, Calmosep.qxd male gender, 11/24/03 family history 5:12 of colon PM Page 1<br />

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thorough consideration. In the presence of these factors,<br />

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23


Gastroenterology<br />

Table 4<br />

Lifestyle and Behavioral Therapy<br />

◗ Exercise regularly<br />

◗ Cognitive–behavioral therapy (stress management, relaxation training)<br />

◗ Diet modification<br />

◗ Increase dietary fiber (25 g/day)<br />

◗ Avoid common culprits: alcohol, chocolate, caffeine, dairy products, sugar-free<br />

sweeteners, gas-<strong>for</strong>ming foods, fatty foods<br />

◗ Avoid chewing gum or drinking through a straw, which can cause air swallowing and<br />

increase gas<br />

◗ Eat smaller meals, especially patients with diarrhea<br />

◗ If lactose intolerant, substitute yogurt <strong>for</strong> milk or use an enzyme<br />

◗ Drink plenty of fluids, especially water<br />

Alternative therapy<br />

◗ Acupuncture<br />

◗ Probiotics<br />

◗ Hypnosis<br />

◗ Yoga, massage, meditation<br />

further diagnostic testing is prudent to<br />

rule out more serious diagnoses (Table 1).<br />

Non-GI symptoms reported by IBS<br />

patients include lethargy, backache, headache,<br />

urinary tract symptoms (nocturia,<br />

frequency, urgency, incomplete bladder<br />

emptying) and in women, dyspareunia.<br />

Half of patients with IBS are depressed,<br />

anxious or hypocondriacal. 2 Be aware of<br />

chronic pain syndromes that can coexist<br />

with IBS (Table 2). Patients with these<br />

syndromes may have more severe IBS.<br />

Many other somatic conditions are<br />

also reported by patients affected by IBS:<br />

mood disorders, anxiety about health,<br />

stressful life events, decreased quality<br />

of life and frequent healthcare seeking. 2<br />

Systematic assessment is important to<br />

identify IBS patients who also have a<br />

psychiatric disorder.<br />

Comorbidities in gluten sensitivity that<br />

may increase clinical suspicion include<br />

geographic tongue, frequent aphthous<br />

ulcers, dermatitis herpeti<strong>for</strong>mis and<br />

chronic iron deficiency anemia. Fatigue<br />

and depression are common to both gluten<br />

sensitivity and celiac disease. Anemia<br />

due to folic acid, B 12 or iron deficiency<br />

may occur in celiac disease. Other symptoms<br />

that should increase clinical suspicion<br />

<strong>for</strong> celiac disease include dental<br />

enamel defects, osteopenia or osteoporosis,<br />

fatigue, bone or joint pain, tingling<br />

of hands or feet, migraine headaches,<br />

and infertility. 2<br />

Celiac disease is typically diagnosed<br />

by serology and small intestine biopsy.<br />

Although both gluten sensitivity and<br />

celiac disease are caused by an inability<br />

to digest gluten, most people with gluten<br />

sensitivity have normal biopsies and those<br />

with celiac disease have small bowel<br />

villous atrophy. Serology tests include<br />

HLA DQ2/DQ8, which has a sensitivity<br />

of 90% to 95%. The specificity <strong>for</strong> this<br />

test is poor. 2<br />

Antibody tests (endomysial, gliadin)<br />

are now recommended as first line due<br />

to high sensitivity and better specificity.<br />

Endoscopy (small intestinal and upper<br />

gastrointestinal with biopsy) is also recommended<br />

to determine the presence of<br />

tissue damage. 1<br />

People with lactose intolerance do<br />

not seem to have the variety of systemic<br />

symptoms experienced by patients with<br />

gluten sensitivity and celiac disease. 17<br />

Elevated levels of breath hydrogen, produced<br />

by bacterial fermentation of lactose<br />

in the colon, help confirm diagnosis<br />

of lactose malabsorption. For this test,<br />

patients ingest a standard dose of lactose<br />

while in a fasting state. Other tests<br />

include intestinal biopsy (to determine<br />

lactase activity) and genetic testing <strong>for</strong><br />

the common polymorphism that is linked<br />

to lactase nonpersistence.<br />

Management<br />

The goal of therapy is to manage symptoms<br />

enough to allow patients to live as<br />

close to normally as possible. Few pharmacologic<br />

agents reduce all symptoms<br />

of IBS (Table 3). Antispasmodics may be<br />

used <strong>for</strong> pain management. The addition<br />

of an antidepressant can be helpful. 2<br />

Antidiarrheals or bulking agents can<br />

help improve quality of life, depending<br />

on symptomology. 2 Patients who experience<br />

IBS due to intolerance of gluten or<br />

lactose must abstain from the offending<br />

substance.<br />

Enzyme supplements taken prior to<br />

the ingestion of dairy products can prevent<br />

IBS symptoms. Patients can also<br />

drink milk products in which lactose has<br />

been prehydrolyzed with lactase enzyme.<br />

Although the availability of gluten-free<br />

food products has increased in recent<br />

years, these products can be more expensive<br />

than traditionally prepared foods.<br />

Patients with gluten sensitivity may<br />

find they need to abstain from dairy<br />

products, not due to lactose intolerance,<br />

but due to casein, a protein that seems to<br />

cause digestive upsets similar to gliadin.<br />

The clinician must become a detective to<br />

ferret out all potential sources of gluten<br />

and casein. For example, casein is found<br />

in many wines.<br />

Lifestyle and behavioral therapy (Table<br />

4) can assist patients with IBS. Cognitive<br />

behavioral therapies can help reduce<br />

stress and anxiety. Dietary modifications,<br />

including increased fiber and fluids and<br />

avoidance of foods that exacerbate symptoms,<br />

can reduce the overall burden of the<br />

disease. The role of alternative therapy is<br />

unproven, but some interventions may<br />

benefit some patients.<br />

Sharon’s Case<br />

Sharon’s physical examination was unremarkable.<br />

She took no medications other<br />

than occasional acetaminophen <strong>for</strong> aches<br />

and pains. Due to the range and variety of<br />

Sharon’s symptoms, her clinician decided<br />

to try an elimination diet starting with<br />

dairy and progressing to gluten. Sharon’s<br />

complete blood count revealed mild iron<br />

deficiency anemia. Her clinician ordered<br />

antigliadin antibody (IgG and IgA) serology<br />

testing. The IgG results were positive<br />

and the IgA results were normal.<br />

Endoscopy revealed no abnormalities,<br />

and duodenal biopsy was normal.<br />

Sharon started taking oral iron supple-<br />

Continued on page 32<br />

24 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


Diabetes<br />

Dave Perillo<br />

Inpatient<br />

Hyperglycemia<br />

A lesson in selecting the correct protocol<br />

By Heidi Rymaszewski, DNP, ANP-BC, BC-ADM, CDE<br />

➼ William, a 49-year-old black<br />

man, presented to the emergency department<br />

with a 1-week history of polyuria,<br />

polydipsia, blurred vision, dizziness and<br />

a 1-day history of vomiting and diarrhea.<br />

His serum blood glucose level at the time<br />

of admission was 1,087 mg/dL. Arterial<br />

pH was 7.34, serum bicarbonate was<br />

25 mEq/L, serum osmolality was 425<br />

mOsm/kg, serum ketones were positive,<br />

and HbA 1c was 12.2%.<br />

The patient had no personal or family<br />

history of diabetes. He reported a past<br />

medical history significant <strong>for</strong> cardiomyopathy,<br />

heart failure (ejection fraction of<br />

20%), pacemaker implant, hypertension,<br />

obstructive sleep apnea and depression.<br />

William was unemployed and receiving<br />

disability payments. He was unmarried,<br />

had no children and lived alone.<br />

His oven did not work and he did not<br />

have a microwave. Most of his meals<br />

were convenience foods purchased at<br />

the gas station and heated on a hot plate.<br />

He quit smoking about 5 years ago. His<br />

alcohol intake was approximately three<br />

12-ounce beers per week, usually during<br />

the weekend. He reported that he did not<br />

use drugs. His exercise was limited due<br />

to shortness of breath.<br />

Physical and Systems Review<br />

The review of systems was negative except<br />

<strong>for</strong> constitutional symptoms. William said<br />

he felt fatigued and that he had lost about<br />

10 pounds over the past 2 to 3 months.<br />

Heidi Rymaszewski is an adult nurse practitioner and certified diabetes educator who works<br />

in the Diabetes and Nutrition Education Department at Aurora Medical Group in Milwaukee.<br />

She has completed a disclosure statement and reports no relationships related to this article.<br />

The patient also reported having blurred<br />

vision <strong>for</strong> the past week; he had not seen<br />

an eye doctor or dentist in years. William<br />

reported one episode of diarrhea and vomiting<br />

of undigested food in the last week.<br />

He complained of poor appetite <strong>for</strong> the<br />

past month. He usually ate two meals daily,<br />

with multiple snacks of junk food. He did<br />

not have a schedule <strong>for</strong> meals, and he often<br />

ate late into the night. He frequently drank<br />

juice and regular cola. He reported that<br />

he had been urinating about five times<br />

per night. He complained of cramping<br />

in both feet, especially in the evening.<br />

William’s physical examination was<br />

normal except <strong>for</strong> a weight of 260 pounds<br />

(BMI 36.2), blood pressure of 170/90<br />

mm Hg, and a mildly elevated pulse at<br />

92 beats per minute. His lips and buccal<br />

mucosa were somewhat dry. Acanthosis<br />

nigricans was present on his neck and<br />

elbows, which is a symptom of insulin<br />

resistance often seen in type 2 diabetes.<br />

The patient was diagnosed with diabetes<br />

(type undetermined at this point)<br />

based on the random blood glucose level<br />

greater than 200 mg/dL. He was placed<br />

on the emergency department’s diabetic<br />

ketoacidosis (DKA) protocol (Table 1)<br />

based on his positive serum ketones. He<br />

was admitted to a general medical unit.<br />

Inpatient Course<br />

William’s glucose level decreased to the<br />

200 mg/dL to 300 mg/dL range after 4<br />

hours of insulin infusion. Finger sticks<br />

every 2 hours showed that it remained in<br />

that range. Adjustment to the infusion<br />

rate was based on the DKA protocol. He<br />

was kept on the same regimen <strong>for</strong> the rest<br />

of that day and half of the following day,<br />

until he was feeling better and began to<br />

experience hunger.<br />

William ate the breakfast provided<br />

to him by the hospital’s dietary department,<br />

and his glucose level be<strong>for</strong>e lunch<br />

increased into the high 300 mg/dL range.<br />

Because his serum ketones were negative<br />

at that point, the hospitalist physician<br />

decided that he should be switched to<br />

a subcutaneous insulin regimen. The<br />

plan was to discharge him later that<br />

day. Because William’s glucose level was<br />

uncontrolled on the insulin infusion<br />

<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

25


Diabetes<br />

and he had already eaten a meal, this<br />

data could not be used to appropriately<br />

calculate his subcutaneous insulin needs.<br />

Two protocols were available: the sliding<br />

scale insulin protocol (Table 2) and<br />

the basal–bolus insulin protocol (Table<br />

3). The hospitalist physician decided to<br />

place William on the sliding scale insulin<br />

protocol. After 4 more hours on this<br />

protocol and another meal, the patient’s<br />

glucose level increased to 450 mg/dL.<br />

Table 1<br />

DKA Insulin Infusion Protocol<br />

Serum ketones were negative. The patient<br />

was returned to the insulin infusion, but<br />

this time he was placed on a general medical<br />

unit insulin infusion protocol that<br />

allowed <strong>for</strong> a higher number of units based<br />

on the results of finger sticks per<strong>for</strong>med<br />

every 2 hours.<br />

After another 4 hours, William’s blood<br />

sugars were in the 180 mg/dL range. The<br />

nursing staff calculated subcutaneous<br />

insulin doses based on insulin infusion<br />

1. Call provider be<strong>for</strong>e any of these orders are instituted.<br />

2. Draw STAT basic metabolic panel, magnesium, phosphorus, serum acetone (if not yet<br />

drawn).<br />

3. Discontinue all previous insulin orders.<br />

4. Give bolus human regular insulin IV ___________ units. Suggested dose 0.1 units/kg.<br />

5. Start infusion of 150 units of human regular insulin in 150 mL 0.9% NaCl (1 unit per<br />

mL) at appropriate insulin infusion rate. (See infusion orders below.) Run first 10–20 mL<br />

of infusion through tubing and waste.<br />

Insulin Infusion Protocol:<br />

CAPILLARY or BLOOD GLUCOSE INSULIN INFUSION<br />

> 500 14 mL/hr (14 units/hr)<br />

401–500 10 mL/hr (10 units/hr)<br />

351–400 8 mL/hr (8 units/hr)<br />

301–350 6 mL/hr (6 units/hr)<br />

251–300 4 mL/hr (4 units/hr)<br />

201–250 3 mL/hr (3 units/hr)<br />

151–200 2 mL/hr (2 units/hr)<br />

100–150 1 mL/hr (1 unit/hr)<br />

< 100 no insulin<br />

6. Capillary or blood glucose every hour. Record on glucose monitoring record. Adjust<br />

insulin infusion based on Insulin Infusion Protocol.<br />

7. If insulin infusion is interrupted due to glucose < 100 mg/dL, obtain capillary or blood<br />

glucose every hour until glucose > 100 mg/dL, then restart insulin infusion.<br />

8. Start IV fluids: _________________________ at __________ mL/hr.<br />

9. For signs of hypoglycemia:<br />

A. Collect STAT capillary or blood glucose. If < 60 mg/dL and symptomatic, stop insulin<br />

infusion and give dextrose 25 g IV (50 mL of D50W).<br />

B. Collect STAT capillary or blood glucose. If blood glucose < 60 mg/dL and the patient is<br />

asymptomatic, stop insulin infusion and give dextrose 12.5 g IV (25 mL of D50W).<br />

C. Recheck capillary or blood glucose in 15–20 minutes. If blood glucose < 60 mg/dL,<br />

repeat above procedure A or B depending on patient’s symptoms and contact physician.<br />

10. When the capillary or blood glucose is less than 300 mg/dL, change IV fluids to D5W<br />

______at ______mL/hr.<br />

Consider discontinuing IV fluids when tolerating by mouth diet.<br />

11. Ask provider about frequency of lab draw:<br />

Electrolyte panel every ______________ Phosphate every ______________<br />

Basic metabolic panel every __________ Serum acetone every ___________<br />

Potassium every ________________ Arterial blood gasses every __________________<br />

Magnesium every _______________ Other: ____________every _______<br />

12. Be<strong>for</strong>e stopping insulin infusion, call provider <strong>for</strong> subcutaneous insulin orders (must<br />

be given 30–60 minutes be<strong>for</strong>e insulin infusion is discontinued).<br />

Provider Signature/ID No: _____________________________________________<br />

Date/Time: __________________<br />

rates over the previous 4 hours, and the<br />

hospitalist physician started the patient<br />

on the basal–bolus insulin protocol. The<br />

nursing staff provided instruction about<br />

blood glucose self-monitoring and insulin<br />

administration, and the hospital provided<br />

a blood glucose meter <strong>for</strong> home use. The<br />

nurses instructed William to check his<br />

blood sugars three times per day and to<br />

bring his meter to the follow-up appointment<br />

with his primary care provider<br />

so that his doses could continue to be<br />

adjusted. He was discharged later that<br />

evening with a blood sugar of 203 mg/dL.<br />

Background<br />

Hospitalized patients with hyperglycemia<br />

are usually categorized as being previously<br />

diagnosed with diabetes, having unrecognized<br />

diabetes, or having hyperglycemia<br />

related to hospitalization. Hyperglycemia<br />

with and without diabetes has been associated<br />

with poor outcomes such as longer<br />

lengths of stay. 1 The American College<br />

of Endocrinologists recommends that<br />

elevated glucose levels (> 140 mg/dL in<br />

patients who are not critically ill) should<br />

be identified in all hospitalized patients<br />

and should be treated aggressively and<br />

as soon as detected. 2<br />

Previously diagnosed diabetes usually<br />

falls into two categories: type 1 (presenting<br />

as diabetic ketoacidosis; DKA)<br />

or type 2 (presenting as hyperosmolar<br />

hyperglycemia state; HHS). The diagnosis<br />

of diabetes has become more complex.<br />

The presentation can be misleading due<br />

to conflicting physical and objective findings.<br />

Often this leads to inappropriate<br />

treatment that produces poor outcomes,<br />

such as immunosuppression, endothelial<br />

dysfunction, inflammation, increased<br />

oxidative stress or thrombosis. 1<br />

William presented to the emergency<br />

department with symptoms similar to<br />

those of someone with type 1 diabetes<br />

(abrupt onset of symptoms and lack of<br />

family history of diabetes). He also had<br />

positive serum ketones, a status typically<br />

present in type 1 diabetes. These<br />

symptoms can also be present in type<br />

2 diabetes, as in HHS. This patient did<br />

not fit the typical physical presentation<br />

of type 1 diabetes. He was an obese black<br />

man with acanthosis nigricans, a condition<br />

often found in type 2 diabetes.<br />

26 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


Diabetes<br />

Unrecognized diabetes is often discovered<br />

when patients are admitted <strong>for</strong><br />

a physiologic stressor such as infection<br />

or myocardial infarction. Hyperglycemia<br />

related to diabetes is usually identified<br />

when the first complete metabolic panel<br />

reveals a fasting blood glucose ≥ 126 mg/<br />

dL, a random blood glucose ≥ 200 mg/<br />

dL, or a hemoglobin A 1c ≥ 6.5%. 3<br />

Hyperglycemia related to hospitalization<br />

may include stress hyperglycemia<br />

Unrecognized diabetes<br />

is often discovered<br />

when patients are<br />

admitted <strong>for</strong> treatment<br />

of a physiologic stressor<br />

such as infection or<br />

heart attack.<br />

Hyperglycemia is usually<br />

identified in a complete<br />

metabolic panel.<br />

resulting from surgical procedures or use<br />

of other medications such as steroids. 4 In<br />

stress hyperglycemia, a patient meets the<br />

criteria <strong>for</strong> hyperglycemia with a random<br />

blood sugar ≥ 140 mg/dL, but he or she<br />

does not meet the hemoglobin A 1c criteria<br />

of > 6.5%. These patients have blood<br />

sugars that often return to normal after<br />

the stress is removed, but they should<br />

be monitored closely <strong>for</strong> development of<br />

prediabetes or diabetes after discharge. 4<br />

Diagnostic Criteria<br />

Diagnose DKA when the blood glucose is<br />

≥ 250 mg/dL, arterial pH is ≤ 7.30, serum<br />

bicarbonate is < 15 mEq/L, and positive<br />

serum ketones are present. 5 Diagnose<br />

HHS when blood glucose is 600 mg/dL or<br />

greater, serum osmolarity is 320 mOsm/<br />

kg or greater, profound dehydration is<br />

present with elevated serum blood urea<br />

nitrogen > 30 mg/dL, small ketonuria are<br />

present, and bicarbonate > 15 mEq/L. 6<br />

Table 2<br />

Sliding Scale Insulin Protocol<br />

Reevaluate insulin orders if on protocol more than 24 to 48 hrs<br />

Nursing Orders<br />

Assessments<br />

__ Metered blood glucose be<strong>for</strong>e meals and at 2100, if able to take nutrition orally<br />

__ Metered blood glucose every 6 hours if patient is not eating by mouth, on total<br />

parenteral nutrition or continuous feedings<br />

__ Metered blood glucose at 0300<br />

__ Metered blood glucose be<strong>for</strong>e meals<br />

__ Metered blood glucose at bedtime<br />

__ Metered blood glucose (specify): ____________<br />

Contingency<br />

__ Notify physician if metered blood glucose is less than 70 mg/dL.<br />

__ Notify physician if metered blood glucose is greater than 180 mg/dL <strong>for</strong> 2 consecutive<br />

checks.<br />

__ Notify physician of any metered blood glucose greater than 300 mg/dL.<br />

Interventions<br />

__ Discontinue all previous sliding scale insulin orders.<br />

__ Discontinue all current insulin infusion orders.<br />

__ If patient is unable to take food by mouth at any time, hold regular/aspart insulin.<br />

__ Administer insulin be<strong>for</strong>e meals only <strong>for</strong> patients taking oral nutrition. (No bedtime<br />

dose given unless provider orders.)<br />

__ Administer insulin every 6 hours <strong>for</strong> patients who are not eating by mouth, on total<br />

parenteral nutrition or continuous feedings.<br />

__ Aspart insulin should be given when food tray is available.<br />

Laboratory<br />

__ Hemoglobin A 1c (GLYH) if not per<strong>for</strong>med within the last 60 days.<br />

Medications<br />

Insulin<br />

• Avoid sliding scale use in poorly controlled type 2 diabetes patients and in all type 1<br />

diabetes patients. If patient not controlled, consider using insulin infusion orders.<br />

• If patient continues to require correctional insulin, consider starting basal–bolus insulin<br />

protocol.<br />

__ NO insulin <strong>for</strong> metered blood glucose less than 150 mg/dL<br />

__ Notify provider and provide NO insulin if metered blood glucose is greater than 400 mg/dL.<br />

Provider Orders<br />

Aspart (Novolog) Insulin Regular Insulin<br />

- If metered blood glucose 150 mg/dL–200 mg/dL, give 2 units or (specify): ________units<br />

- If metered blood glucose 201 mg/dL–250 mg/dL, give 4 units or (specify): ________units<br />

- If metered blood glucose 251 mg/dL–300 mg/dL, give 6 units or (specify): ________units<br />

- If metered blood glucose 301 mg/dL–350 mg/dL, give 8 units or (specify): ________units<br />

- If metered blood glucose 351 mg/dL–400 mg/dL, give 10 units or (specify): ________units<br />

Provider Signature/ID No: _____________________________________________<br />

Date/Time: __________________<br />

Diagnostic Tests<br />

Order hemoglobin A 1c testing on all<br />

patients with a known diagnosis of diabetes<br />

if a previous value collected within<br />

the prior 2 to 3 months is not available. 4<br />

Also order this test <strong>for</strong> any patient with<br />

a blood glucose level > 140 mg/dL.<br />

Values > 6.5% suggest that the patient<br />

had diabetes be<strong>for</strong>e admission. 1 Blood<br />

glucose targets on noncritical care units<br />

are premeal < 140 mg/dL and random<br />

blood glucose < 180 mg/dL. 4<br />

Clinical Management<br />

In the hospital setting, insulin therapy is<br />

the preferred method of glycemic control<br />

<strong>for</strong> patients with diabetes. No data<br />

about the safety and efficacy of inpatient<br />

administration of oral agents have been<br />

published.<br />

Oral medications have a limited role<br />

in the management of hyperglycemia<br />

<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

27


Diabetes<br />

when patients with diabetes are ill and<br />

hospitalized. 4<br />

Hospitalized patients are prone to large<br />

variances in blood glucose levels. Because<br />

of this, effective treatment is required to<br />

maintain good glucose control. There<br />

are, however, different schools of thought<br />

when it comes to the best way to treat<br />

hyperglycemia in the hospital setting.<br />

Treatment options include continuous<br />

insulin infusions, sliding scale insulin<br />

and basal/bolus insulin therapy. 4<br />

In the critical care setting and when<br />

DKA is suspected, insulin infusions are<br />

the standard of care. 7 When it is time to<br />

transition off the infusion, the insulin<br />

Table 3<br />

Basal–Bolus Insulin Protocol<br />

A. Discontinue all prior insulin orders<br />

B. Blood glucose level goals<br />

• Preprandial: 70–140 mg/dL<br />

• 2-hour postprandial: < 180 mg/dL<br />

C. Blood Glucose Monitoring Frequency<br />

• Check blood glucose within 30 minutes prior to each meal and at bedtime.<br />

Basal Insulin<br />

Breakfast<br />

0730<br />

Dinner<br />

1630<br />

Bedtime<br />

2100<br />

NPH _______ units _______ units ______units<br />

Glargine (Lantus) _______units _______ units _______units<br />

Detemir (Levemir) _______units _______units _______units<br />

D. Basal Insulin Dosing Schedule: Administer subcutaneously as follows<br />

Bolus Insulin<br />

Breakfast<br />

0730<br />

Lunch<br />

1130<br />

Dinner<br />

1630<br />

Aspart (Novolog) _____units ______units _____units<br />

E. Bolus Insulin Dosing Schedule: Administer subcutaneously as follows<br />

Regular (Novolin) _____units ______units ______units<br />

F. Bolus Insulin Correction Dose: Give in addition to scheduled bolus insulin based on the<br />

premeal blood glucose<br />

• Consider “low” dose <strong>for</strong> insulin-sensitive patients<br />

• Consider “high” dose <strong>for</strong> very insulin-resistant patients<br />

Glucose Level Low Medium High Other<br />

< 60 mg/dL Hold Hold Hold Hold<br />

61–90 mg/dL −2 units −2 units −3 units ____units<br />

91–119 mg/dL 0 units 0 units 0 units ____units<br />

120–149 mg/dL 0 units +1 unit +2 units ____units<br />

150–199 mg/dL +1 unit +2 units +3 units ____units<br />

200–249 mg/dL +2 units +3 units +4 units ____units<br />

250–299 mg/dL +3 units +5 units +7 units ____units<br />

300–349 mg/dL +4 units +7 units +10 units ____units<br />

350 mg/dL or > +5 units +8 units +12 units ____units<br />

_______________________Provider Signature Date_____ Time__________<br />

infusion rates are essential to determining<br />

initial subcutaneous insulin doses. 7 If the<br />

patient has achieved blood sugar control<br />

on the infusion, incorrect doses may be<br />

calculated <strong>for</strong> subcutaneous injection.<br />

When a patient is ready to eat a meal<br />

and is on a nonacute care unit, scheduled<br />

subcutaneous insulin that delivers basal,<br />

nutritional (bolus) and correction (supplemental)<br />

doses are preferred. This is also<br />

known as basal–bolus insulin therapy. 4<br />

Practice Implications<br />

<strong>NPs</strong> and <strong>PAs</strong> need to be familiar with<br />

evidence-based practice <strong>for</strong> managing<br />

hyperglycemia in the hospital setting.<br />

They also need to be prepared to intervene<br />

quickly when a particular protocol is<br />

not effectively controlling hyperglycemia.<br />

This case study highlights the significance<br />

of making the right choice <strong>for</strong> each particular<br />

patient when managing hyperglycemia<br />

in the hospital setting. The correct<br />

choice of initial protocol — or timely<br />

change to an evidence-based basal–bolus<br />

insulin protocol when available — can<br />

provide better control of hyperglycemia<br />

earlier, thereby decreasing the patient’s<br />

length of stay. ■<br />

References<br />

1. Arnold LM, Keller DL. Hyperglycemia management<br />

in non-critically ill hospitalized patients. J Pharm<br />

Pract. 2009;22(5):467-477.<br />

2. Handelsman Y, Mechanick JI, Blonde L, et al.<br />

American Association of Clinical Endocrinologists medical<br />

guidelines <strong>for</strong> clinical practice <strong>for</strong> the management<br />

of diabetes mellitus. Endocr Pract. 2011;17(Suppl 2):1-53.<br />

3. Bloomgarden ZT. A1C: Recommendations, debates,<br />

and questions. Diabetes Care. 2009;32(12):e141-e147.<br />

4. American Diabetes Association. Standards of<br />

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5. Kitabchi AE, et al. Hyperglycemic crises in adult<br />

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1343.<br />

6. Nugent BW. Hyperosmolar hyperglycemic state.<br />

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Irritable Bowel<br />

Continued from page 24<br />

ments and a multivitamin.<br />

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References<br />

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Irritable Bowel Syndrome. http://digestive.niddk.nih.gov/<br />

ddiseases/pubs/ibs/.<br />

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3. Longstreth GF, et al. Functional bowel disorders.<br />

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4. Thompson WG, et al. Irritable bowel syndrome in<br />

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5. Müller-Lissner SA, et al. Epidemiological aspects of<br />

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Digestion. 2001;64(3):200-204.<br />

6. Inadomi JM, et al. Systematic review: the economic<br />

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Ther. 2003;18(7):671-682.<br />

7. Long KH, et al. The economics of coeliac disease:<br />

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2010;32(2):261-269.<br />

8. Smith GD, et al. Health-related quality of life and<br />

symptom classification in patients with irritable bowel<br />

syndrome. J Nurs Healthc Chronic Illn. 2010;2(1):4-12.<br />

9. DiBonaventura M, et al. Health-related quality<br />

of life, work productivity and health care resource use<br />

associated with constipation predominant irritable bowel<br />

syndrome. Curr Med Res Opin. 2011;27(11):2213-2222.<br />

10. Rodrigues LA, Ruigomez A. Increased risk of irritable<br />

bowel syndrome after bacterial gastroenteritis: cohort<br />

study. BMJ. 1999;318(7183):565–566.<br />

11. Spiller RC, et al. Increased rectal mucosal enteroendocrine<br />

cells, T lymphocytes and increased gut permeability<br />

following acute Campylobacter enteritis and in post-dysenteric<br />

irritable bowel syndrome. Gut. 2000;47(6):804-811.<br />

12. Zar S, et al. Food specific serum IgG4 and IgE titres<br />

to common food antigens in irritable bowel syndrome.<br />

Am J Gastroenterol. 2005;100(7):1550-1557.<br />

13. Ferguson A, et al. Clinical and pathological spectrum<br />

of coeliac disease: active, silent, latent, potential. Gut.<br />

1993;34(2):150-151.<br />

14. Troncone R, et al. The spectrum of gluten sensitivity.<br />

Proceedings of the 8th International Symposium on<br />

Coeliac Disease, Naples, Italy, April 1999.<br />

15. Troncone R, et al. Gluten sensitivity in a subset of<br />

children with insulin dependent diabetes mellitus. Am<br />

J Gastroenterol. 2003;98(3):590-595.<br />

16. Verdu EF, et al. Between celiac and irritable bowel<br />

syndrome: The “no man’s land” of gluten sensitivity. Am<br />

J Gastroenterol. 2009;104(6):1587-1594.<br />

17. Suchy FJ, et al. NIH Consensus Development<br />

Conference: Lactose Intolerance and Health. Ann Intern<br />

Med. 2010;152(12):792-796.<br />

32 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


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Career Opportunities<br />

healthcare providers in 2011.<br />

—Lynn A. Kelso, MSN, APRN,<br />

FCCM, FAANP, in the February 2012<br />

issue of <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong>.<br />

Looking <strong>for</strong> a new<br />

career opportunity<br />

Surgical Infection<br />

Each month, the <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong><br />

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convenience, listings are arranged by region,<br />

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These positions are also posted and updated<br />

daily at the “Jobs” tab at our website, www.<br />

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Surgical site infections affect 750,000<br />

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—Robert M. Blumm, MA, PA-C,<br />

DFAAPA, in the February 2012 issue<br />

of <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong>.<br />

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LOWER —Debra SOUTH Schuerman, ATLANTIC NP, Duke University building on the skills<br />

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in<br />

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entry-level PA programs was 156.<br />

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in the October 2011 issue<br />

of <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong>.<br />

Celebrating <strong>NPs</strong><br />

GET MORE FROM<br />

In 2011, approximately 150,000 <strong>NPs</strong><br />

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and think versatility.<br />

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40. Men who do not have a history that<br />

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NATIONAL<br />

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NEW ENGLAND<br />

Only 12% to 20% of psychiatric<br />

patients require medications to control<br />

NEW ENGLAND<br />

their conditions.<br />

PACIFIC —Ashlea McLeod, MPAS, PA-C,<br />

and Colleen Clemency Cordes, PhD,<br />

PACIFIC<br />

in the June 2011 issue of<br />

PACIFIC <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong>.<br />

Family Nurse Practitioner<br />

SOUTHWEST<br />

Opportunities<br />

Asthma SOUTHWEST Prevalence<br />

The<br />

Asthma<br />

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UPPER SOUTH health<br />

in childhood,<br />

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Family<br />

Nurse<br />

ment<br />

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with<br />

than<br />

WEST Bachelor<br />

$3 billion<br />

NORTH of<br />

per<br />

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year.<br />

CENTRAL Graduate of<br />

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and WEST 2-4 years NORTH of clinical CENTRAL experience.<br />

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As WEST a National NORTH Health CENTRAL Service Core<br />

Approved Kristy WEST L. Oden, Site, SOUTH DNP, school FNP-BC, CENTRAL loan repayment MSN,<br />

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Please <strong>for</strong>ward spicy foods, your alcohol, resume chocolate,<br />

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dchristian@providencechc.org<br />

Reported or in fax: the 401-444-0469<br />

August 2011 issue of<br />

<strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong>.<br />

Inflammatory<br />

Breast Cancer<br />

Julie A. Nelson, DNP, RNC-OB, WHNP-BC,<br />

Deepa Patel, BSN, CCRN, ANP-S, and<br />

Peggy Mancuso, PhD, RN, CNM, listed<br />

redness and color change, swelling,<br />

induration or ridges, skin thickening,<br />

heaviness or fullness in breast, sensation<br />

of heat in breast, palpable lymph<br />

nodes, sudden increase in breast size,<br />

little or no response to antibiotic treatment,<br />

and rapid progression of symptoms<br />

as key clinical features of inflammatory<br />

breast cancer in the October<br />

2011 issue of <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong>.<br />

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38 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


Massachusetts, New Hampshire<br />

Come work with us!<br />

NURSE PRACTITIONERS<br />

<strong>Full</strong>-Time & Per Diem<br />

MIT Medical seeks nurse practitioners to<br />

collaborate with physicians on the provision<br />

of primary and urgent care to patients. Will<br />

assess patient’s health status through<br />

interview and physical exam and synthesize<br />

this clinical in<strong>for</strong>mation to <strong>for</strong>mulate health<br />

problem(s) and appropriate treatment<br />

strategies, and provide health maintenance<br />

and health promotion <strong>for</strong> patients and their<br />

families. Will provide these services according<br />

to age-specific plans of care.<br />

Requirements: current certification/licensure<br />

as a nurse practitioner, current CPR<br />

certification, and two years of experience as<br />

a nurse practitioner in a relevant age-specific<br />

ambulatory setting. Experience in dermatology<br />

a plus. Hospital-based RN experience<br />

preferred.<br />

MIT Medical is a large multidisciplinary group<br />

practice serving students, employees,<br />

retirees, and families of the MIT community.<br />

We have over 25 medical specialties, our own<br />

HMO, a JCAHO-accredited outpatient facility,<br />

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best hospitals in the Boston area. For more<br />

in<strong>for</strong>mation about MIT Medical, please visit<br />

our website at http://medweb.mit.edu.<br />

Interested candidates may apply on-line at<br />

http://jobs.mit.edu. Please reference job<br />

number mit-00008337 and indicate where<br />

you saw this posting. Please indicate in<br />

your cover letter whether you are applying<br />

<strong>for</strong> the <strong>Full</strong>-Time or Per Diem position.<br />

Nurse Practitioners & Physician Assistants<br />

life works here.<br />

Nurse Practitioners:<br />

• Neurology - .5 Inpatient/.5 MS Outpatient Clinic<br />

• Headache Clinic<br />

• Critical Care<br />

• Radiology<br />

• GIM<br />

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• Palliative Medicine (.5)<br />

• Neonatology<br />

• Part-time Certified Nurse Midwife<br />

Physician Assistants:<br />

• Neurology - .5 Inpatient/.5 MS Outpatient Clinic<br />

• Dermatology<br />

• Neonatology<br />

Qualified candidates will have completed an<br />

accredited nurse practitioner or physician assistant<br />

program and be eligible <strong>for</strong> NH licensure. Academic<br />

preparation at a Masters level is preferred.<br />

Please apply online at:<br />

www.Dartmouth-Hitchcock.org<br />

Career Opportunities<br />

MIT is an equal opportunity/affirmative action<br />

employer. Applications from women, minorities,<br />

veterans, older workers,<br />

and individuals with<br />

disabilities are strongly<br />

encouraged.<br />

http://medweb.mit.edu<br />

Planned Parenthood League of MA seeks Part-time<br />

Traveling Mid-Level Clinician in GYN Services to work in<br />

Central MA and Springfield. Provide reproductive health<br />

service, including medical abortion to patients in an efficient<br />

manner. Certifications in CPR, as adult, family or family<br />

planning NP, MSN. Clinical knowledge in women’s health and<br />

reproductive care. Strong interpersonal skills and ability to<br />

relate to varying demographics in a non-judgemental way.<br />

Ability to work in a fast paced environment and function as a<br />

part of a medical team. Comprehensive benefit package.<br />

To apply please visit our website at, www.pplm.org<br />

EOE<br />

One Medical Center Drive • Lebanon, NH • 03756<br />

We are an equal opportunity employer.<br />

DELIVERED DIRECTLY TO<br />

YOU —THE <strong>ADVANCE</strong><br />

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<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

39


l<br />

hile<br />

ed<br />

the<br />

er<br />

.<br />

Career Opportunities<br />

NURSE PRACTITIONER OPPORTUNITY<br />

JOIN THE HEALTHCARE TEAM AT<br />

BERKSHIRE MEDICAL CENTER!<br />

Berkshire Medical Center, a 302-bed community<br />

teaching hospital and level II Trauma Center, is currently<br />

seeking exceptional MA licensed, or license<br />

eligible, Nurse Practitioners in the following areas:<br />

PRIMARY CARE<br />

CARDIOLOGY<br />

SURGICAL SERVICES<br />

OCCUPATIONAL MEDICINE<br />

URGENT CARE<br />

PSYCH GERIATRIC<br />

Berkshire Medical Center is the region’s leading provider<br />

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award-winning programs, nationally-recognized<br />

physicians, world-class technology<br />

and a sincere commitment to the community,<br />

we are delivering the kind of advance<br />

health care most commonly found in large<br />

metropolitan centers.<br />

Berkshire Health System offers a competitive salary<br />

and benefits package, as well as the opportunity to<br />

work in an environment where you will be challenged,<br />

supported, and respected. Relocation assistance<br />

offered as well. For more in<strong>for</strong>mation about how you<br />

can become a part of our team, please contact:<br />

Antoinette Lentine<br />

Berkshire Medical Center<br />

725 North St., Pittsfi eld, MA 01201<br />

Phone: (413) 395-7866<br />

Fax: (413) 496-6817<br />

E-mail: alentine@bhs1.org<br />

Please visit our website at<br />

www.berkshirehealthsystems.com<br />

Job Satisfaction<br />

<strong>NPs</strong> consider continuing education support,<br />

monetary bonuses in addition to<br />

salary, and opportunity to receive compensation<br />

<strong>for</strong> services outside normal<br />

duties on the job less important than<br />

intrinsic factors. They are most satisfied<br />

by percentage of time spent in direct<br />

patient care, sense of accomplishment,<br />

and ability to deliver quality care.<br />

—Ann Priebe, MSN, ACNP-BC,<br />

in the February 2012 issue of<br />

<strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong>.<br />

Stony Brook Medicine<br />

www.stonybrook.edu/jobs<br />

PA Demand<br />

(See our ad on page 38.)<br />

The American Academy of Physician<br />

40 <strong>ADVANCE</strong> Assistants <strong>for</strong> NP reported & <strong>PAs</strong> in September 2011<br />

LOWER SOUTH ATLANTIC<br />

MIDDLE ATLANTIC<br />

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EOE<br />

MIDDLE ATLANTIC<br />

MIDDLE ATLANTIC<br />

MOUNTAIN<br />

Bridan Healthcare, a leading provider of continence and wound care management services<br />

in long-term care, assisted living, and independent (including in-home) facilities, is currently<br />

seeking to ll positions <strong>for</strong> Nurse Practitioners & Advance Practice Nurses nationwide with at<br />

least 2 years clinical experience with wounds care and/or continence management experience.<br />

MOUNTAIN<br />

MOUNTAIN<br />

NATIONAL<br />

Bridan Healthcare is an equal opportunity employer. We have a culture of excellence which drives<br />

our hiring process. We’re not just looking <strong>for</strong> the most qualied candidate; we also want to make<br />

sure that candidate ts into the culture of passionate patient care that we have already established.<br />

NATIONAL<br />

If you are passionate about patient care, enjoy helping to restore dignity to patients, and have<br />

a minimum NATIONAL of 2 years of Wound Management experience and/or certied as a WOCN or WCC,<br />

we would like to get to know you. Interested candidates should submit their CV or resume with<br />

a cover NEW letter ENGLAND including salary requirements to Aaron Fulton at fultona@bridanhc.com or mail<br />

directly to:<br />

NEW Bridan ENGLAND Healthcare | attn: Aaron Fulton | PO Box 685 | Rancocas, NJ 08073<br />

Bridan Healthcare: Repairing integrity; regaining control; restoring dignity.<br />

NEW ENGLAND<br />

PACIFIC<br />

PACIFIC North Philadelphia Health System is seeking<br />

motivated individuals to join our team in the following areas:<br />

PACIFIC Assistant Nurse Manager (Critical Care)<br />

This full-time position requires a minimum of 3 years critical care experience (preferably ICU).<br />

BSN and previous supervisory experience desired. Current PA RN license required.<br />

SOUTHWEST<br />

Compliance Auditor (Behavioral Health)<br />

SOUTHWEST<br />

Healthcare Administration degree and previous Per<strong>for</strong>mance Improvement experience is required.<br />

SOUTHWEST<br />

Emergency Room Nurses<br />

Part-time and Flex with minimum one year experience.<br />

UPPER SOUTH ATLANTIC<br />

Nurse Practitioner<br />

This full-time position requires a Current PA CRNP with CPR/ACLS certifi cation.<br />

UPPER SOUTH ATLANTIC<br />

A minimum of 5 years experience in related fi eld preferred.<br />

UPPER SOUTH Competitive ATLANTIC Pay Rates • <strong>Full</strong> Benefits • Free Parking and More!!!<br />

Qualifi ed candidates should <strong>for</strong>ward their resume to:<br />

WEST NORTH CENTRAL North Philadelphia Health System<br />

WEST NORTH CENTRAL Attn: Human Resources<br />

WEST NORTH CENTRAL<br />

WEST SOUTH CENTRAL<br />

WEST SOUTH CENTRAL<br />

WEST SOUTH CENTRAL<br />

www.bridanhc.com<br />

This full-time position requires 3 years medical/surgical, critical care and behavioral health experience. BSN or<br />

Negative Effects<br />

of Smoking<br />

801 W. Girard Avenue, Philadelphia, PA 19122<br />

E-mail: sbarnett@nphs.com • Fax: 215-787-2195<br />

www.nphs.com<br />

EOE M/F/D/V<br />

Cigarette smoking increases the risk <strong>for</strong><br />

stroke, cataracts, gum disease, acne,<br />

has a hand in our service excellence and growth.<br />

COPD, heartburn, decreased blood flow,<br />

ulcers, erectile dysfunction, infertility, and<br />

osteoporosis. It also increases the risk<br />

<strong>for</strong> multiple cancers throughout the body.<br />

Hyperglycemia<br />

The Interested prevalence candidates of posttransplant may submit their resume diabetes<br />

to HR Dept. via<br />

fax: 201-848-5279 or e-mail: humanresources@chccnj.org,<br />

301<br />

mellitus<br />

Sicomac<br />

after<br />

Avenue,<br />

liver<br />

Wyckoff,<br />

transplantation<br />

NJ 07481<br />

can be as high as 31% to 38%, noted<br />

To learn more visit our web site at www.chccnj.org<br />

Katherine Monday, MSN, NP, in the<br />

February 2012 issue of <strong>ADVANCE</strong> <strong>for</strong><br />

301 Sicomac Avenue • Wyckoff, NJ 07481 EOE M/F/D/V<br />

<strong>NPs</strong> & <strong>PAs</strong>.<br />

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Ministering to other’s needs with a warm hand could be the start of a great career. Our mission is<br />

focused on the broadening continuum of high-quality, family-centered services to enhance the lives<br />

of the elderly and mental health population—not to mention the life of every single employee who<br />

Why not join us and find all you’re capable of We’re currently recruiting <strong>for</strong>:<br />

Advanced Practice Nurse<br />

<strong>Full</strong> Time opportunity <strong>for</strong> an experienced APN to work in a long term care and post<br />

acute care setting as an independent practitioner in collaboration with the<br />

physician. MSN required with five years APN experience in an acute care or<br />

geriatric setting. NJ RN licensure with prescription authority required.


Pennsylvania, New Jersey, New York<br />

CRNP/CRNP Manager<br />

Eagleville Hospital is hiring a CRNP to manage our Gero-Psychiatric<br />

Department. Additional CRNP position in substance abuse<br />

and co-occurring disorders. Hours are flexible; may be some<br />

rotating weekends. The CRNP is responsible <strong>for</strong> admission physical<br />

exams, providing acute care medical and psychiatric services,<br />

and assisting in managing medications. Qualified candidates will<br />

have a Masters of Science in Nursing, a valid CRNP license, and<br />

a certification in Psychiatry. Successful candidates should have 5<br />

years of nursing experience. Previous experience working with<br />

geriatric and/or mental health patients preferred. Management<br />

experience and good interpersonal communication skills a plus.<br />

Career Opportunities<br />

We offer a competitive salary and benefits package<br />

including 403(b), PTO,<br />

health/dental/vision insurance, EAP, etc.<br />

To apply, e-mail: hr@eaglevillehospital.org<br />

or fax: 610-539-8319.<br />

EOE<br />

FAMILY NURSE PRACTITIONER<br />

or PHYSICIAN ASSISTANT<br />

Article 28 diagnostic & treatment center<br />

based in Brookville, NY seeks<br />

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medical/psychiatric conditions. Provider<br />

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with strong clinical support services in an<br />

innovative practice utilizing electronic<br />

health records. Computer proficiency<br />

required. 21-28 flexible hour per week<br />

plus some evenings required.<br />

Competitive salary and excellent<br />

benefits package.<br />

Fax resume to 516-686-4420<br />

or Email: pbirong@advantagecaredtc.org<br />

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Nurse Practitioner<br />

Seeking full time individual to provide pre-operative assessment, diagnosis,<br />

treatment, education and post-operative care to GYN surgical oncology patients.<br />

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nurse with prescriptive privileges and a minimum of 2 years experience in an<br />

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preferred. Excellent clinical and communication skills and computer proficiency<br />

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applicants, please email resume to: debra.savage@mountainsidehosp.com, mail:<br />

HackensackUMC Mountainside, Attn: Debra Savage, RN, BA, Manager,<br />

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fax: 973-680-7961.<br />

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FAIRMOUNT<br />

BEHAVIORAL HEALTH SYSTEM<br />

NURSE PRACTITIONER<br />

Family Practice (Part Time and Per Diem available)<br />

Fairmount Behavioral Health System, a leading provider of Psychiatric<br />

Services <strong>for</strong> Adults, Adolescents and Children in Philadelphia, has immediate<br />

openings <strong>for</strong> Part Time and Per Diem Family NP.<br />

Responsibilities include admission physicals and daily consult care with followups<br />

<strong>for</strong> patients in behavioral health inpatient treatment in collaboration with<br />

or under the direction of a physician licensed in PA. Primary responsibilities<br />

will include: H&P’s as per hospital guidelines, assisting physician with medical<br />

consults and in the care and treatment of patients within licensure guidelines.<br />

Must have strong clinical skills and high motivation.<br />

Must be licensed Family NP in PA. Part Time and Per Diem positions are<br />

weekends and/or evenings.<br />

Interested candidates should apply via website:<br />

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<br />

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Pennsylvania, New Jersey, New York<br />

Career Opportunities<br />

CARON TREATMENT CENTERS, internationally recognized <strong>for</strong> excellence in<br />

addiction treatment, is seeking the following:<br />

Certified Nurse Practitioner<br />

Responsibilities include completing medical history and physical exams on<br />

patients, initiating orders <strong>for</strong> medications, per<strong>for</strong>ming clinical procedures, initiating<br />

evaluation in emergency situations, providing counseling and instruction<br />

regarding common patient problems, and working as part of a multidisciplinary<br />

treatment team. Requires certification by the State of PA as a CRNP<br />

and the American Nurses Credentialing Center, three yrs exp. as a CRNP. Prior<br />

experience working in the chemical dependency field is preferred.<br />

We offer an excellent benefits package including a generous 401(K) plan.<br />

Please submit resume and salary requirements to:<br />

Caron Treatment Centers, Galen Hall Road,<br />

PO Box 150, Wernersville, PA 19565.<br />

Fax: 610-678-8583<br />

Email: recruiter@caron.org<br />

www.caron.org<br />

COME JOIN OUR TEAM<br />

Cardiothoracic experience NP or PA<br />

<strong>Full</strong>-time, day shift, rounding every other weekend.<br />

St. Joseph Medical Center has an opportunity <strong>for</strong> a NP or PA with<br />

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<strong>for</strong> surgical assisting and vein harvesting as well as following patients of<br />

the floor.<br />

To learn more about this opportunity please visit our website at<br />

www.thefutureofhealthcare.org<br />

42 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

St. Joseph Medical Center - Human Resources<br />

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Catholic Health Initiatives and its organizations are<br />

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—Robert M. Blumm, MA, PA-C,<br />

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New Jersey, Pennsylvania<br />

DEBORAH<br />

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We are currently seeking an Advance<br />

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HOLY REDEEMER ST. JOSEPH MANOR<br />

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HOLY REDEEMER LAFAYETTE<br />

8580 Verree Rd., Philadelphia, PA<br />

Nurse Practitioner - Opportunities available in Long Term Care/Short Stay Rehab<br />

As a Geriatric Nurse Practitioner, you will provide a high level of holistic care and services <strong>for</strong><br />

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will act as a liaison to physicians to ensure all resident and family needs are being met. The<br />

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EOE<br />

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Private physician owned and<br />

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• Mercer County - Community hospital with<br />

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• Middlesex County - Community-teaching<br />

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Career Opportunities<br />

Mercy LIFE<br />

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is seeking a full-time<br />

Nurse Practitioner.<br />

The Nurse Practitioner provides primary<br />

medical management in collaboration<br />

with the LIFE Physician(s). Provides daily<br />

oversight of LIFE Clinic. Rounds in<br />

the LIFE contracted nursing home and<br />

hospitals. Conducts initial assessments<br />

and periodic reassessments, plan of<br />

care, coordination of 24 hour care<br />

delivery, regularly in<strong>for</strong>ming the IDT of the<br />

medical, functional, and psychosocial<br />

condition of each participant, remaining<br />

alert to pertinent input from other team<br />

members, participant’s caregivers, as well<br />

as documenting changes in a participant’s<br />

medical record consistent with documentation<br />

policies established by the medical<br />

director. Master’s degree in nursing,<br />

Gerontological preferred. Licensed RN<br />

in the State of Pennsylvania with current<br />

certification as a Nurse Practitioner.<br />

Bilingual Spanish speaking preferred. One<br />

year experience in working with geriatric<br />

population. One year of experience with<br />

a frail or elderly population.<br />

Interested candidates<br />

please apply online at:<br />

www.mercyhealth.org<br />

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Members of LifeBridge Health, Sinai Hospital of Baltimore, and Northwest Hospital,<br />

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Opportunities <strong>for</strong> Nurse Practitioners<br />

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EOE<br />

44 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


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46 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


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47


Career Opportunities<br />

MAKE A HEALTHY CHANGE<br />

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MinuteClinic Family Nurse Practitioners are today’s<br />

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•Southeastern Regional Medical Center, Lumberton, NC<br />

Rhode Island:<br />

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Enjoy excellent compensation, comprehensive benefi ts (<strong>Full</strong> Health, 401k match, Profi t Sharing, PTO and Professional<br />

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Where We Work:<br />

University of New Mexico Hospitals<br />

More Than 80 <strong>NPs</strong> & <strong>PAs</strong> Provide Care Across Specialties<br />

Albuquerque<br />

➼ UNIVERSITY OF NEW MEXICO (UNM)<br />

Hospitals provides quality care to citizens of<br />

Albuquerque and specialized care to patients of<br />

all ages throughout New Mexico via the UNM<br />

Health System, including UNM School of<br />

Medicine, College of Nursing and Pharmacy<br />

and the UNM Medical Group.<br />

The hospital employs more than 80 APRNs<br />

and <strong>PAs</strong> who work in more than 30 primary<br />

care and specialty care clinics associated with<br />

University of New Mexico Hospitals. Staff<br />

APRNs and <strong>PAs</strong> work in more than 20 specialties<br />

including, but not limited to, primary care,<br />

family planning, women’s health, orthopedics,<br />

sports medicine, plastics, rheumatology, adult<br />

and pediatric neurology, adult and pediatric<br />

cardiology, urology, endoscopy, and diabetes.<br />

“We are unique in that we are a teaching<br />

facility, including medical assistants, nursing<br />

students, advanced practice registered nurses,<br />

physician assistants, medical residents and<br />

other disciplines,” said Kori Kindred, BSN,<br />

MSN, CFNP, DNP-S, executive director of<br />

ambulatory providers at UNM Hospitals.<br />

“We also pride ourselves on our diversity,<br />

ethnicity and inclusion department and have a<br />

very strong interpreter services department<br />

using live interpreters, video monitors and of<br />

course, access to the interpreter phones.”<br />

Kindred is seeking to hire six full-time <strong>PAs</strong><br />

or APRNs with CPR certification <strong>for</strong> primary<br />

care positions at Southwest Mesa Clinic,<br />

Westside Clinic, After Hours Clinic and<br />

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positions are open in the disciplines of orthospine,<br />

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The ideal candidates will be strong team<br />

players with a positive attitude and flexibility.<br />

“We value high-quality care and are proud of<br />

our Patient-Centered Medical Home designation<br />

in our primary care clinics,” Kindred said.<br />

New graduates are encouraged to apply.<br />

"We provide additional training and mentoring<br />

<strong>for</strong> new graduates and offer them time in<br />

specialty clinics if additional training is needed,”<br />

Kindred said.<br />

UNM Hospitals offers a competitive salary<br />

with medical benefits, incentives, tuition<br />

reimbursement and continuing education. ■<br />

For more in<strong>for</strong>mation, contact Kori Kindred at<br />

KKindred@salud.unm.edu or (505)272-9676.<br />

4 August 2012 • <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong> • www.advanceweb.com/NPPA<br />

48 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


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<strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong><br />

49


Comments&Feedback<br />

<strong>NPs</strong> & <strong>PAs</strong> Do the Math<br />

By Jennifer Ford<br />

Readers continue to share their comments — positive and negative — on news, articles and blogs posted by <strong>ADVANCE</strong><br />

<strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong>. It all adds up to an excellent opportunity to network with colleagues. Here are some recent posts.<br />

+<br />

Addition<br />

AANP and ACNP announced their plans to consolidate the<br />

two groups. Readers shared positive reactions on Facebook<br />

and the <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong> Blog:<br />

❝ Long overdue. ❞<br />

❝<br />

This is a wonderful opportunity <strong>for</strong> there is strength in<br />

numbers.<br />

❞<br />

❝ Great news <strong>for</strong> the merger … we need one voice. Thanks. ❞<br />

❝<br />

I am excited about the possibilities associated with this<br />

merger.<br />

❞<br />

❝<br />

So glad to hear that these two professional associations<br />

will be merging and no longer have ‘divided camps.’ It is<br />

important now with our financial climate and ACA going<br />

<strong>for</strong>ward that we have one collective voice in the political<br />

arena. Can’t wait.<br />

❞<br />

❝<br />

It’s about time. This was so confusing to have 2 organizations<br />

and to decide which one to join. I hope there is no<br />

‘squabbling’ between the two over names and who does<br />

what. I anticipate that our professional organizations will<br />

have a professional transition.<br />

❞<br />

÷<br />

−<br />

Subtraction<br />

“The Forked Tongue of Convenient<br />

Care” by Stephen Lyons, PA, appeared<br />

in Opinions & Essays at www.advanceweb.com/NPPA<br />

and presented a negative<br />

view that got a lot of attention.<br />

❝<br />

I have been a PA since 1977 and<br />

have never heard of such restrictions.<br />

I am certain that your story was hard<br />

to tell, but it is even more difficult to<br />

believe. I could not work in such an<br />

environment.<br />

❞<br />

❝<br />

Stephen, thank you so much <strong>for</strong><br />

the enlightenment. I will be attending<br />

PA school in August 2012 and it is<br />

very helpful to know about what circumstances<br />

I will have to face when I<br />

start working in the field and know how<br />

to be ready <strong>for</strong> them. There definitely<br />

is a dichotomy in terms of what they<br />

are calling convenient care and what<br />

really is convenient and af<strong>for</strong>dable<br />

healthcare. Hopefully one day this can<br />

all be rectified.<br />

❞<br />

Division<br />

In the <strong>ADVANCE</strong> <strong>for</strong> <strong>NPs</strong> & <strong>PAs</strong> video coverage of the AAPA IMPACT 2012 conference in Toronto, the separation is<br />

still clear between two groups of <strong>PAs</strong>: those who wish to change the name of the profession and those who don’t.<br />

Visit www.advanceweb.com/NPPAmultimedia to see which PA leaders said the following:<br />

❝ If this is an issue among so many physician assistants, they would like to see that this is being discussed. ❞<br />

❝<br />

In this house we spend a lot of time gazing at our navel and dissecting it … it seems to me that we need to<br />

be worried about more relevant issues.<br />

❞<br />

50 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>


Help give<br />

them freedom<br />

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52 <strong>ADVANCE</strong> <strong>for</strong> NP & <strong>PAs</strong>

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