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Is A calorie Always A calorie - Gardner 8Oct - Stanford University

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Insulin sensitivity/resistance<br />

Moderator of success with high-carb vs. low-carb weight loss<br />

Obese, non-diabetic women<br />

4-month feeding study<br />

Hypocaloric diet<br />

Hi-Carb/Lo-Fat = 60:20<br />

Lo-Carb/Hi-Fat = 40:40<br />

CONCLUSIONS:<br />

Hi-Carb/Lo-Fat more effective<br />

for insulin sensitive women<br />

Lo-Carb/Hi-Fat more effective<br />

for insulin resistant women<br />

Differences not explained by<br />

changes in intake, activity or<br />

resting metabolic rate<br />

Weight Loss (kg)<br />

0<br />

2<br />

4<br />

6<br />

8<br />

10<br />

12<br />

14<br />

Insulin Sensitive<br />

Fasting Insulin

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