Report 2008-2010

Grants 1995-2010
FRAMEWORK 7 PROGRAMME
Strengthening and Sustaining the European Perspectives of Molecular Biotechnology in Lithuania (MoBiLi) 2009-2013
Metastatic tumours facilitated by hypoxic tumour micro-environments (METOXIA)
Development of novel antiviral drugs against Influenza (FLUCURE) 2010-2014
Pan-european network for the study and clinical management of drug resistant tuberculosis (TB PAN-NET) 2008-2013
Small molecule inhibitors of the trimeric influenza virus polymerase complex (FLUINHIBIT) 2008-2010
FRAMEWORK 6 PROGRAMME
Meganucleases for gene replacement 2006-2008
Inhibition of cancer by disrupting interaction between polo-like kinase 1 polo-box domain and spindle targets 2006-2008
A multidisciplinary approach to the study of DNA enzymes down to the single molecule level 2005-2009
Targeting newly discovered oxygen sensing cascades for novel cancer treatments, biology equipment, drugs 2004-2008
Molecular modeling-based characterization of protein complexes involved in DNA repair 2004-2006
Drug design by structural thermodynamics 2004-2006
ScanBalt Competence Region – a model case to enhance European competitiveness in life sciences, 2004-2006
genomics and biotechnology for health on a global scale
Rational design and comparative evaluation of novel genetic vaccines 2004-2008
FRAMEWORK 5 PROGRAMME
Support for the integration of newly associated states in the European research area 2003-2006
“Biotechnology Centre of Excellence of Lithuania”
Development of highly special enzymes for genome manipulation 2003-2004
Enhanced Laboratory Surveillance of Measles 2002-2005
Combined immune and gene therapy for chronic hepatitis 2001-2003
Comprehensive risk analysis of dioxins: development of methodology to assess genetic susceptibility 2000-2003
to developmental disturbances and cancer
Bivalent hantavirus vaccine for Europe: Different approaches and evaluation in animal models 1999-2003
FRAMEWORK 4 PROGRAMME
Molecular monitoring and pathological role of HCV, HGV and altered HBV genomes in the Baltic countries 1998-2001
Detection, identification and typing of the Mycobacterium tuberculosis in the Baltic countries 1998-2003
Recombinant viral particulate proteins as tools for new vaccines and diagnostics 1994-1997
HOWARD HUGHES MEDICAL INSTITUTE
Structural characterization of protein interactions in DNA replication, repair 2006-2010
and recombination processes through molecular modeling
Towards engineering of restriction enzymes 2003-2004
Bioinformatics-guided engineering of DNA methyltransferases 2003-2004
Sequence recognition and base flipping by DNA methyltransferases: Structural studies and redesign for novel functions 2001-2005
Principles of restriction enzymes specificity 2001-2005
Combination of improved methods with expert knowledge to derive models of protein structure at low sequence homology 2001-2005
Mechanisms of specific protein-DNA recognition and modification 1996-2000
NATIONAL INSTITUTE OF HEALTH
Methylome profiling via DNA Methyltransferase directed labeling 2008-2010
Approaches for genomic mapping of 5-hydroxymethylcytosine a novel epigenetic mark in mammalian DNA 2010-2012
WELLCOME TRUST
Cross-talk between functional domains of BfiI restriction endonuclease 2005-2006
Restriction enzymes with novel restriction mechanisms 2001-2003
Calorimetric studies of DNA- restriction enzyme interactions 1999-2001
INTERNATIONAL BUREAU OF THE BMBF
New cofactors for methyltransferases 2004-2005
Human tumour vaccines based on chimeric virus-like particles 2002-2005
Bivalent Hantavirus vaccine for Europe based on recombinant proteins 2001-2003
35 th anniversary
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