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Report 2008-2010

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1997<br />

1999<br />

2000<br />

2001<br />

2002<br />

2004<br />

Doctoral thesis, habilitation procedure 1997-<strong>2010</strong><br />

Name Title Supervisor<br />

A. Lubys Cloning and analysis of genes encoding type II restriction modification enzymes Bsp6I, Cfr9I ir HphI Prof. A. Janulaitis<br />

A. Lagunavičius Structural and functional relation of restriction endonuclease MunI Dr. V. Šikšnys<br />

R. Skirgaila Structural and functional relation of restriction enzyme Cfr10I Dr. V. Šikšnys<br />

K. Stankevičius Characterization of atypical type II restriction-modification enzymes Bpu10I and Eco47I-Eco47II Prof. A. Janulaitis<br />

A. Timinskas Comparative analysis of amino acid sequences of DNA methyltransferases Prof. A. Janulaitis<br />

G. Vilkaitis Functional and kinetic analysis of HhaI DNA methyltransferase ant its Thr-250 mutants Prof. dr. S. Klimašauskas<br />

S. Serva DNA base flipping by cytosine methyltransferase HhaI. Prof. dr. S. Klimašauskas<br />

D. Bartkevičiūtė Construction of systems for heterologous protein secretion in yeast Prof. K. Sasnauskas<br />

J. Vitkutė Screening and characterization of type II restriction enzymes Prof. A. Janulaitis<br />

E. Mištinienė Structure and properties of tumor associated antigen UK114 and its homologue protein p14.5 Prof. G. Dienys,<br />

Dr. V. Naktinis<br />

R. Rimšelienė Construction of restriction endonuclease Eco57I mutants with altered sequence specificity Prof. A. Janulaitis<br />

G. Sasnauskas Novel subtype of type IIs restriction enzymes Dr. V. Šikšnys<br />

M. Zaveckas Partitioning and refolding of recombinant human granulocyte-colony stimulating factor Dr. D. Matulis<br />

2005<br />

in aqueous two-phase systems containing chelated metal ions<br />

Dr. H. Pesliakas<br />

2006 R. Slibinskas Synthesis of mumps and measles virus proteins in yeast and their use in diagnostics Prof. K. Sasnauskas<br />

D. Daujotytė DNA binding and active base flippinng by the Hha methyltransferase Prof. dr. S. Klimašauskas<br />

N. Pozdniakovaitė Human P14.5 gene characterization in normal and tumor cells Dr. V. Popendikytė<br />

M. Zaremba Structure – stability – function correlations within the tetrameric restriction endonuclease Bse634I Prof. V. Šikšnys<br />

E. Merkienė DNA methyltransferase HhaI: conformational changes and interactions with substrates Prof. dr. S. Klimašauskas<br />

2007 G. Tamulaitienė Crystallographic and functional investigations of type ii restriction endonucleases Eco57I and SdaI Prof. dr. V. Šikšnys<br />

Dr. S. Gražulis<br />

A. Jakubauskas Domain organization analysis of type II restriction endonucleases Prof. dr. V. Šikšnys<br />

G. Lukinavičius Sequence-Specific Labeling of DNA via methyltransferase-directed transfer of activated groups (MTAG) Prof. dr. S. Klimašauskas<br />

E. Kriukienė Restriction endonuclease MnlI – a member of the HNH family of nucleases Dr. A. Lubys<br />

<strong>2008</strong> R. Petraitytė Synthesis of viral proteins in yeast and their application for diagnostics Prof. K. Sasnauskas,<br />

Dr. A. Ražanskienė<br />

A. Bulavaitė Synthesis of chimeric polyomavirus MPyV, SV40 and hepatitis B virus surface proteins in yeast and Prof. K. Sasnauskas<br />

the study of their properties<br />

L. Antoniukas Large-scale production and purification of hantavirus nucleocapsid protein in yeast Saccharomyces Prof. K. Sasnauskas<br />

cerevisiae for diagnostics and vaccine applications<br />

Prof. U. Reichl<br />

Habil. dr. R. Ulrich<br />

S. Jurėnaitė Enginnering of bifunctional restriction endonucleases with novel specifities Dr. A. Lubys<br />

-Urbanavičienė<br />

Dr. Č. Venclovas<br />

R. Šapranauskas Investigation of type IIS restriction endonuclease BfiI domain organization by using a new random Dr. A. Lubys<br />

gene dissection approach<br />

G. Tamulaitis Structural and functional studies of the Ecl18kI and EcoRII restriction enzymes specific Prof. dr. V. Šikšnys<br />

for interrupted palindromic sites<br />

2009 R. Sukackaitė Structural and functional studies of the restriction endonuclease BpuJI Prof. dr. V. Šikšnys<br />

Dr. S. Gražulis<br />

<strong>2010</strong> R. Ražanskas Interaction of hepatitis B virus core protein and its mutant forms with human liver proteins Prof. K. Sasnauskas<br />

2005<br />

<strong>2008</strong><br />

Habilitation procedure passed in Vilnius University<br />

V. Šikšnys Structure and function of restriction endonucleases recognizing related sequences<br />

A. Gedvilaitė Gene expression in yeast: molecular exploration and application<br />

A. Žvirblienė Development and application of monoclonal antibodies<br />

35 th anniversary<br />

12

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