Inflammatory Bowel Disease - IAGH

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Difference of UC and CD • CRC in UC is most common in the rectum and sigmoid colon • CRC in CD is distributed between the right colon and rectosigmoid • Synchronous tumors are much more common in IBD than in sporadic CRC (12% versus 3 to 5% )
Who is at Risk • UC and CD • Extensive disease ( proximal to splenic flexure or more than 30% of colon, risk was significantly increased in those with extensive or pancolitis ) • Long duration of disease ( > 7y) • Young age at symptom onset • PSC ( right colon, role of bile acids and protective effect of UDCA) • Chronic inflammation (significant correlation between the severity of inflammation as assessed by histology)
Page 2 and 3: Farhad zamani Associated professor
Page 5 and 6: Pathogenesis • Different than for
Page 7: Crohn's disease and CRC • The ris
Page 11 and 12: •Until further data are available
Page 13 and 14: Chromoendoscopy • Topical applica
Page 20: Narrow Band Imaging • NBI employs
Page 27 and 28: Prevention of CRC • Primary preve
Page 29 and 30: Folic acid • Folate deficiency in
Page 31: Conclusions • 5-ASA & folic acid

Inflammatory Bowel Disease - IAGH

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