quality control & gmp of vati/gutika - amam-ayurveda.org
quality control & gmp of vati/gutika - amam-ayurveda.org
quality control & gmp of vati/gutika - amam-ayurveda.org
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GMP/Q.C FOR TABLETS CONT….<br />
• Picking<br />
• Definition: ‘Picking’ is the term used when a small<br />
amount <strong>of</strong> material from a tablet is sticking to and<br />
being removed <strong>of</strong>f from the tablet-surface by a<br />
punch face.<br />
• The problem is more prevalent on the upper punch<br />
faces than on the lower ones. The problem worsens,<br />
if tablets are repeatedly manufactured in this station<br />
<strong>of</strong> tooling because <strong>of</strong> the more and more material<br />
getting added to the already stuck material on the<br />
punch face.<br />
• Reason: Picking is <strong>of</strong> particular concern when punch<br />
tips have engraving or embossing letters, as well as<br />
the granular material is improperly dried.