quality control & gmp of vati/gutika - amam-ayurveda.org
quality control & gmp of vati/gutika - amam-ayurveda.org
quality control & gmp of vati/gutika - amam-ayurveda.org
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GMP/Q.C FOR TABLETS CONT….<br />
• Binding<br />
• Definition: ‘Binding’ in the die, is the term<br />
used when the tablets adhere, seize or tear in<br />
the die. A film is formed in the die and ejection<br />
<strong>of</strong> tablet is hindered. With excessive binding,<br />
the tablet sides are cracked and it may crumble<br />
apart.<br />
• Reason: Binding is usually due to excessive<br />
amount <strong>of</strong> moisture in granules, lack <strong>of</strong><br />
lubrication and/or use <strong>of</strong> worn dies.