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quality control & gmp of vati/gutika - amam-ayurveda.org

quality control & gmp of vati/gutika - amam-ayurveda.org

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GMP/Q.C FOR TABLETS CONT….<br />

• Binding<br />

• Definition: ‘Binding’ in the die, is the term<br />

used when the tablets adhere, seize or tear in<br />

the die. A film is formed in the die and ejection<br />

<strong>of</strong> tablet is hindered. With excessive binding,<br />

the tablet sides are cracked and it may crumble<br />

apart.<br />

• Reason: Binding is usually due to excessive<br />

amount <strong>of</strong> moisture in granules, lack <strong>of</strong><br />

lubrication and/or use <strong>of</strong> worn dies.

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