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chapter 10, early development and axis formation in amphibians part-2

chapter 10, early development and axis formation in amphibians part-2

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Control of neural specification by the<br />

levels of BMPs<br />

Whole mount <strong>in</strong> situ hybridization of Sox2, which is a specific mRNA <strong>in</strong><br />

neural tube <br />

Control<br />

Hyper BMPs by morphol<strong>in</strong>o.<br />

Lack of Sox2 expression <strong>in</strong><br />

neural tube<br />

Control<br />

Hypo BMPs<br />

Epidermis is <strong>in</strong>structed by BMP<br />

signal<strong>in</strong>g, <strong>and</strong> the organizer works by<br />

block<strong>in</strong>g the BMP signal from reach<strong>in</strong>g<br />

the ectoderm above it.<br />

Lack of ventral-dorsal <strong>axis</strong> <strong>in</strong><br />

neural tube

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