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chapter 10, early development and axis formation in amphibians part-2

chapter 10, early development and axis formation in amphibians part-2

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Trunk <strong>in</strong>duction: The Wnt signal<strong>in</strong>g pathway<br />

<strong>and</strong> posteriorization of the neural tube<br />

-caten<strong>in</strong> density <strong>in</strong> future neural plate<br />

Chang<strong>in</strong>g the level of Wnt signal<strong>in</strong>g alters the expression of<br />

regionally specific markers <strong>in</strong> neurula. <br />

Control +Xwnt8 +Xfrzb1<br />

Less anterior<br />

More anterior<br />

Bf1, forebra<strong>in</strong>; Otx2, forebra<strong>in</strong> & midbra<strong>in</strong>; Krox20, two region of h<strong>in</strong>dbra<strong>in</strong>

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