Cellular Defenses Against Radiation-Induced Carcinogenesis:
Cellular Defenses Against Radiation-Induced Carcinogenesis:
Cellular Defenses Against Radiation-Induced Carcinogenesis:
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• At least two checkpoints are responsive to DNA damage:<br />
1. G1-S transition<br />
2. G2-M transition<br />
• In mammalian cells the G1-S checkpoint is best understood.<br />
NCI REB <strong>Radiation</strong> Epidemiology Course, May 14, 2007<br />
TJJ