Introduction to Enzyme and Coenzyme Chemistry - E-Library Home

OPO 3
2−
OH
O
HO
HO
H 3 N
2− O3 PO
OPO 3
2−
OPO 3
2−
2−
OPO 3
Lys 229 Lys 229 Lys229
H H 2−
OPO 3
2−
OPO 3
H 2 N N H 2
H
N N Lys 229
O
OH OH
H
− O
Glu
187 OH
OH
R
H O
H S
OH
O
Glu 187 O
Glu187
O
2−
OPO 3
H 2 N Lys 229
O
NHLys 229
NHLys 229
OH
Glu 187
H
OH
Lys 146
H 3 N Lys 146
H
H 3 N
O
O
2− O3 PO
HO
HO OH
+
+
O −
Asp 33
O
2− O3 PO
146 O −
O H
Lys H H
O
Asp Asp 33 no G3P
33 O
O
HO
H
2 H2 O
OPO 3
2−
1 H
O
2 H
OH
Figure 7.5 Mechanism for rabbit muscle class I fructose-1,6-bisphosphate aldolase.