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Pharmaceutical<br />
Lipid Nanocarriers in Cancer Diagnosis and Therapy<br />
Edited by<br />
Eliana Souto<br />
This book introduces fundamental principles of lipid nanocarriers science relevant to cancer therapy. The first in this field, it fills<br />
a need for an accurate, coherent and authoritative introduction to lipid nanocarriers focusing in cancer therapy; both because<br />
of the growing popularity of these modern drug delivery systems and also because of the emergent need of dealing with cancer<br />
treatment.<br />
Active drug delivery and targeting using nanobiotechnologies has become one of the most successful strategies to approach<br />
chemotherapy. This book deals with lipid nanocarriers for targeted delivery to tum<strong>our</strong>s of various organs and combination of<br />
these with other methods of treatment of cancer such as radiotherapy, diagnostic and imaging analysis. Lipid nanocarriers are<br />
also used for gene therapy for cancer.<br />
Also addressed is how diagnostic strategies with lipid nanocarriers can be combined with therapeutics, which will be important<br />
for the personalized management of cancer.<br />
Cancer chemotherapeutic drugs are also being used as immunosuppressive agents in the chronic treatment of non-neoplastic<br />
diseases. The scientific research in this field has been focused on the development of strategies to target and deliver several<br />
cancer chemotherapeutic drugs to decrease citotoxicity. These include both carrier- and receptor-mediated nanocarriers. Being<br />
biodegradable and biocompatible systems, lipid nanocarriers have been extensively explored to increase its therapeutic index,<br />
reducing adverse side effects to ultimately extend life-span of patients.<br />
Furthermore, a familiarity with lipid materials science will enable scientists to conduct rational performulation studies, to<br />
understand and optimize formulations, drug delivery systems and their manufacturing processes as well as associated process<br />
analytical technologies and quality by design.<br />
PUBLICATION DATE: JULY 2011<br />
FORMAT: Hardback ISBN: 9781847354778 GB: £130 US: $215 EU: €165<br />
FORMAT: Paperback ISBN: 9781847354785 GB: £90 US: $150 EU: €115<br />
FORMAT: eBOOK ISBN: 9781847354792 GB: £130 US: $215 EU: €165<br />
Polysaccharides in Medicinal and Pharmaceutical Applications<br />
Edited by<br />
Valentin Popa<br />
This book presents new and specific aspects in the field of polysaccharides and their derivatives recommended for use in<br />
medicine and pharmacy. At the same time the aspects developed in this book will be useful to designing new systems for drugs<br />
delivery, immunomodulation, and new materials based on polysaccharides isolated from different s<strong>our</strong>ces and their derivatives.<br />
The structure and properties of polysaccharides from different s<strong>our</strong>ces with potential applications in the fields of medicine<br />
and pharmacy are discussed. Thus, the structural aspects concerning hyaluronic acids, fungal extra cellular polysaccharides,<br />
celluloses, alginates, hemicelluloses, dextran, glyconjugates and cyclodextrins are covered. The applications are described both<br />
for nonmodified and modified forms of polysaccharides for drug delivery, immunomodulation, tissue engineering and hydrogel<br />
preparation.<br />
PUBLICATION DATE: JUNE 2011<br />
FORMAT: Hardback ISBN: 9781847354365 GB: £160 US: $265 EU: €200<br />
FORMAT: Paperback ISBN: 9781847354372 GB: £135 US: $220 EU: €170<br />
FORMAT: eBOOK ISBN: 9781847354389 GB: £160 US: $265 EU: €200<br />
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