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Pharmaceutical<br />

Lipid Nanocarriers in Cancer Diagnosis and Therapy<br />

Edited by<br />

Eliana Souto<br />

This book introduces fundamental principles of lipid nanocarriers science relevant to cancer therapy. The first in this field, it fills<br />

a need for an accurate, coherent and authoritative introduction to lipid nanocarriers focusing in cancer therapy; both because<br />

of the growing popularity of these modern drug delivery systems and also because of the emergent need of dealing with cancer<br />

treatment.<br />

Active drug delivery and targeting using nanobiotechnologies has become one of the most successful strategies to approach<br />

chemotherapy. This book deals with lipid nanocarriers for targeted delivery to tum<strong>our</strong>s of various organs and combination of<br />

these with other methods of treatment of cancer such as radiotherapy, diagnostic and imaging analysis. Lipid nanocarriers are<br />

also used for gene therapy for cancer.<br />

Also addressed is how diagnostic strategies with lipid nanocarriers can be combined with therapeutics, which will be important<br />

for the personalized management of cancer.<br />

Cancer chemotherapeutic drugs are also being used as immunosuppressive agents in the chronic treatment of non-neoplastic<br />

diseases. The scientific research in this field has been focused on the development of strategies to target and deliver several<br />

cancer chemotherapeutic drugs to decrease citotoxicity. These include both carrier- and receptor-mediated nanocarriers. Being<br />

biodegradable and biocompatible systems, lipid nanocarriers have been extensively explored to increase its therapeutic index,<br />

reducing adverse side effects to ultimately extend life-span of patients.<br />

Furthermore, a familiarity with lipid materials science will enable scientists to conduct rational performulation studies, to<br />

understand and optimize formulations, drug delivery systems and their manufacturing processes as well as associated process<br />

analytical technologies and quality by design.<br />

PUBLICATION DATE: JULY 2011<br />

FORMAT: Hardback ISBN: 9781847354778 GB: £130 US: $215 EU: €165<br />

FORMAT: Paperback ISBN: 9781847354785 GB: £90 US: $150 EU: €115<br />

FORMAT: eBOOK ISBN: 9781847354792 GB: £130 US: $215 EU: €165<br />

Polysaccharides in Medicinal and Pharmaceutical Applications<br />

Edited by<br />

Valentin Popa<br />

This book presents new and specific aspects in the field of polysaccharides and their derivatives recommended for use in<br />

medicine and pharmacy. At the same time the aspects developed in this book will be useful to designing new systems for drugs<br />

delivery, immunomodulation, and new materials based on polysaccharides isolated from different s<strong>our</strong>ces and their derivatives.<br />

The structure and properties of polysaccharides from different s<strong>our</strong>ces with potential applications in the fields of medicine<br />

and pharmacy are discussed. Thus, the structural aspects concerning hyaluronic acids, fungal extra cellular polysaccharides,<br />

celluloses, alginates, hemicelluloses, dextran, glyconjugates and cyclodextrins are covered. The applications are described both<br />

for nonmodified and modified forms of polysaccharides for drug delivery, immunomodulation, tissue engineering and hydrogel<br />

preparation.<br />

PUBLICATION DATE: JUNE 2011<br />

FORMAT: Hardback ISBN: 9781847354365 GB: £160 US: $265 EU: €200<br />

FORMAT: Paperback ISBN: 9781847354372 GB: £135 US: $220 EU: €170<br />

FORMAT: eBOOK ISBN: 9781847354389 GB: £160 US: $265 EU: €200<br />

28:<br />

To place an order, visit <strong>our</strong> website:www.polymer-books.com

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