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Part 3 Quiz Version - Sinoe medical homepage.

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Cardiology – <strong>Part</strong> 3<br />

<strong>Quiz</strong><br />

25.5) Which of the following beta-blockers has a long half-life and therefore can be<br />

administered once daily, is used in the prevention of re-bleeding in the setting of bleeding<br />

secondary to portal hypertension, and is used for glaucoma<br />

a) Metoprolol<br />

b) Nadolol, Carteolol, Atenolol, Betaxolol, Bisoprolol<br />

c) Pindolol, Acebutolol, Penbutolol<br />

d) Labetalol, Carvedilol<br />

e) Esmolol<br />

26) Which of the following is NOT an indication for beta-blockers<br />

a) Mitral valve prolapse<br />

b) Migraine prophylaxis<br />

c) Asthmatic crisis<br />

d) Essential tremor<br />

e) Hypertension<br />

27) What is the first-dose phenomenon seen when administering the alpha1-blocking<br />

agents prazosin (Minipress), terazosin (Hytrin), and doxazosin (Cardura)<br />

a) Retention of sodium and water<br />

b) Positive test for antinuclear factor<br />

c) Drop in standing blood pressure<br />

d) Extreme dizziness and palpitations<br />

e) Lassitude<br />

28) Polypharmacy is rationalized in the administration of vasodilators with<br />

antihypertensive medications as each drugs works on one set of interacting, mutually<br />

compensatory regulatory mechanisms for maintaining blood pressure.<br />

a) True<br />

b) False, one drug should be given at a time<br />

c) False, vasodilators and antihypertensives oppose each other<br />

29) Vasodilator therapy does NOT cause orthostatic hypotension or sexual dysfunction<br />

because:<br />

a) They do not affect the parasympathetic system<br />

b) The sympathetic reflexes are intact<br />

c) The baroreceptor reflex is blunted<br />

d) Salt and water retention compensate<br />

e) Co-administration with other drugs is required<br />

30) Which of the following is a vasodilator with high first-pass liver metabolism, has<br />

pharmacokinetics that include rapid versus slow acetylators, and may cause SLE-like<br />

symptoms<br />

a) Diazoxide (Proglycem)<br />

b) Fenoldopam (Corlopam)<br />

c) Nitroprusside (Nitropress)<br />

d) Minoxidil (Rogaine)<br />

e) Hydralazine (Apresoline)<br />

31) Which of the following opens potassium channels in smooth muscle and must be<br />

administered with a beta-blocker and a loop diuretic<br />

a) Minoxidil (Rogaine)<br />

b) Diazoxide (Proglycem)<br />

<strong>Version</strong>: 16Oct2008 Page 32 of 60

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