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Congress Abstracts full PDF - International Council of Medical ...

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ACUPUNCTURE ENHANCES SUPEROXIDE DISMUTASE (SOD) ACTIVITY IN THE SERUM OF RHEUMATOID<br />

ARTHRITIS PATIENTS<br />

Seung-Tae Kim 1,2 , Yun-Ju Kim 3 , Ji-Young Lee 1 , Hyangsook Lee 1,4 , Changshik Yin 1 , Sun-Mi Choi 5 , Younbyoung Chae 1,2 ,<br />

Hyejung Lee 1,2 , Hi-Joon Park 1,2<br />

1<br />

Acupuncture & Meridian Science Research Center; 2 Department <strong>of</strong> Meridian & Acupoint, College <strong>of</strong> Korean Medicine,<br />

Kyung-Hee University, Seoul Republic <strong>of</strong> Korea; 3 Korea Centers for Disease Control and Prevention, Seoul, Republic<br />

<strong>of</strong> Korea; 4 College <strong>of</strong> Korean Medicine, Sangji University, Wonju, Republic <strong>of</strong> Korea; 5 Department <strong>of</strong> <strong>Medical</strong><br />

Research, Korea Institute <strong>of</strong> Oriental Medicine, Daejeon, Republic <strong>of</strong> Korea<br />

Rheumatoid arthritis (RA) is a chronic autoimmune disease, principally characterized by synovial inflammation <strong>of</strong><br />

the joints. Oxidative stress plays a major role in the pathogenesis <strong>of</strong> RA. Thus, we investigated whether acupuncture<br />

would elicit any changes in the levels <strong>of</strong> antioxidants, such as superoxide dismutase (SOD) and catalase, or the total<br />

antioxidant status (TAS) in the serum <strong>of</strong> RA patients. Twenty-one patients who met the American College <strong>of</strong><br />

Rheumatology (ACR) criteria for RA underwent 14 sessions <strong>of</strong> partially individualized acupuncture treatment for 6<br />

weeks. Changes in the activities <strong>of</strong> SOD and catalase, the TAS and the swollen joint counts were assessed at baseline<br />

and after 6 weeks <strong>of</strong> treatment. In results, acupuncture significantly increased the activities <strong>of</strong> SOD and catalase, but<br />

it did not have a significant effect on TAS. Moreover, acupuncture reduced the number <strong>of</strong> swollen joints and this<br />

reduction was associated with enhanced SOD activity. In conclusion, these findings indicate that acupuncture might<br />

relieve the symptoms <strong>of</strong> RA by modulating oxidative stress.<br />

ACUPUNCTURE FOR PREMENSTRUAL SYNDROME: A SYSTEMATIC REVIEW OF RANDOMIZED<br />

CONTROLLED TRIALS<br />

Song-Yi Kim, Younbyoung Chae, Hyejung Lee, Hi-Joon Park<br />

Acupuncture and Meridian Science Research Center (AMSRC), Kyung Hee University, 1 Hoegi-dong,<br />

Dongdaemun-gu, Seoul, Republic <strong>of</strong> Korea<br />

Objective: The aim <strong>of</strong> this systematic review is to summarize and critically evaluate the evidence for the<br />

effectiveness <strong>of</strong> the acupuncture on the premenstrual syndrome (PMS).<br />

Methods: Systematic searches were conducted on 6 electronic databases and 3 relevant journals until December<br />

2007. Hand searches included conference proceedings and our own files. There were no restrictions regarding the<br />

language <strong>of</strong> publication. Methodological quality was assessed using the Jadad score.<br />

Results: Nine randomized clinical trials (RCTs) met our inclusion criteria. Two types <strong>of</strong> control procedures were<br />

used: invasive needle control (n=3) or medication (n=6). All RCTs suggested beneficial effects on the improvement<br />

<strong>of</strong> overall premenstrual symptoms compare with control group, whilst most trials suffered from methodological flaws<br />

such as inadequate study design, small sample size and poor reporting. Meta-analysis <strong>of</strong> 6 RCTs showed a significant<br />

effect <strong>of</strong> acupuncture compared with medication for PMS (3.27 <strong>of</strong> odd ratio, 95% CI [2.16, 4.96], P

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