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STUDY ON ANTI-ALLERGIC EFFECST OF GANODERMA LUCIDUM PHARMACOPUNCTURE AND
GANODERMA LUCIDUM EXTRACT
Hyun-Min Yoon, Won-Il Kim, Kyung-Hwa Kang
Dept. of Acupuncture, College of Oriental Medicine, Dong-Eui University
Objectives: We studied on anti-allergic effects of Ganoderma lucidum herbal acupuncture(GHA) and Ganoderma
lucidum extract(GE).
Methods: In vivo, Animals were herbal-acupunctured GHA at both B13s three times for 5 days. Then, we
investigated compound 48/80-induced active systemic anaphylatic shock using ICR mice and anti-DNP IgE-induced
passive cutaneous anaphylaxis using Sprague Dawley rat. In vitro, we measured cell viability, b-hexosaminidase
release, IL-4 and TNF-a from RBL-2H3 cells, and nitric oxide from Raw264.7 cell after treatment of GE of various
concentrations.
Results: In vivo, GHA pretreatments at both B13s inhibited compound 48/80-induced active systemic anaphylatic
shock. Passive cutaneous anaphylaxis were inhibited by GHA10 and OP. In vitro, 0.1 ~ 2% GE treatments were not
affect on cell viability and inhibited b-hexosaminidase release, IL-4, TNF-a and nitric oxide.
Conclusions: These results suggest that GHA and GE may be beneficial in the inhibition of allergic inflammatory
response.
ACUPUNCTURE ATTENUATE WITHDRAWAL SYMPTOMS AND AUTONOMIC RESPONSES TO SMOKING-
RELATED VISUAL CUES
Chae Younbyoung 1 , Jong-Woo Kim 2 , Hi-Joon Park 1 , O-Seok Kang 1 , Song-Yi Kim 1 , Hwa-Jin Lee 1 , Chang-Sik Yin 1 ,
Hyejung Lee 1 *
1
Dept Meridian and Acupuncture point, College of Oriental Medicine, Kyung Hee University, 1 Hoegi-dong,
Dongdaemun-gu, Seoul, Republic of Korea; 2 Dept Oriental Neuropsychiatry, Kyung Hee University East-West Neo
Medical Center, Seoul, Republic of Korea
In smokers, smoking-associated cues produce smoking urges and cravings, which are accompanied by autonomic
dysfunction in response to these cues. We investigated whether acupuncture ameliorated cigarette withdrawal
symptoms, and attenuated the autonomic responses to smoking-related visual cues in smokers, using a power
spectrum analysis of heart rate variability (HRV). Fifteen subjects were treated real acupuncture (RA) at HT7 and 14
subjects received with sham acupuncture (SA) at LI10 using the Park Sham Device. The cigarette withdrawal scale
(CWS) was measured on the 3rd day after quitting smoking. The low frequency/high frequency (LF/HF) ratio of the
HRV was compared between the RA and SA groups during the distraction task using neutral or smoking visual cues.
The CWS of the RA group was significantly lower than that of the SA group. The increase in the LF/HF ratio of HRV
induced by the smoking-related visual cues was significantly lower in the RA group, as compared to the SA group.
Acupuncture not only ameliorated cigarette withdrawal, but also attenuated the autonomic responses to smoking
cues during withdrawal. These findings suggest that acupuncture might help in smoking cessation by attenuating
withdrawal symptoms and smoking cues-induced autonomic responses.
Keywords: Acupuncture, Addiction, Withdrawal, Autonomic, Visual Cues
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