Thyroid gland

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The chemical structure of thyroid hormones
SYNTHESIS AND RELEASE OF THYROID HORMONES 1. IODINE TRAPPING (iodine pump) <strong>Thyroid</strong>/Serum free iodine = 25 TSH-dependent – Hypophysectomy: T/S = 5 TSH (iodine deficiency) T/S = 250 LATS TSH iodine uptake - absorption 100-150 μg/day Na/J (Na/iodine symporter [NIS] inhibited by PERCHLORATE (ClO 4 ), THIOCYANATE (SCN - ), PERTECHNATe (TcO 4 ), NITRATE (NO 3 ), (competition); LITHIUM. 2. IODINE-OXYDATION Iodide leaves the cell via pendrin (anion exchanger I - /Cl - ) MICROVILLI - PEROXIDASE (Inhibited by propylthiouracil) 3. SYNTHESIS OF THYREOGLOBULIN MW: 660 kDa, GLYCOPROTEIN acinar cells, ribosomal synthesis
Page 1: THE THYROID GLAND
Page 4 and 5: "Für seine Arbeiten über Physiolo
Page 6 and 7: The concept of radioactive tracing
Page 8 and 9: Thyroid gland: 15-25 g Blood flow:
Page 12 and 13: 4. EXOCYTOSIS Excytosis of thyreogl
Page 14 and 15: Hormone transport T3 (Half life: 24
Page 16 and 17: DEIODINATION 5’/3’-Deiodase Typ
Page 18 and 19: Effects of thyroid hormones I GENOM
Page 20 and 21: Frog metamorphosis: from tadpole to
Page 22: REGULATION OF THYROID HORMONE SECRE
Page 27 and 28: pyro-Glu-His-Pro Glykoprotein, 28 k
Page 29 and 30: Iodine metabolism
Page 31 and 32: DISEASES OF THE THYROID GLAND 1835/
Page 33 and 34: Graves disease owes its name to the
Page 35 and 36: Hyperthyreosis Morbus Basedow-Grave
Page 37 and 38: HYPOTHYREOSIS - HYPOTHYROIDISM The
Page 39 and 40: Role of the thyroid gland in the po
Page 41: Stumpen rauchender Kretine. Ein nic

Thyroid gland

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