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Thyroid gland

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Hormone transport<br />

T3 (Half life: 24h) and T4 (Half life: 8d)<br />

> 99.5% protein-bound<br />

bound: T 4 =99.98%; T 3 =99.5%<br />

Only the free hormone is biologically active!!<br />

(prevention of filtration in the kidney,<br />

buffer, reserve)<br />

THYROXINE BINDING GLOBULIN (TBG, 54 kDa Glycoprotein)<br />

THYROXINE BINDING PREALBUMIN (TBPA)<br />

ALBUMIN

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