Thyroid gland
Thyroid gland
Thyroid gland
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Effects of TSH<br />
TSH stimulates:<br />
Iodine uptake by follicle cells<br />
[Na/I cotransporter (symporter)]<br />
Iodination<br />
Conjugation (MIT, DIT → T 3 , T 4 )<br />
Endocytosis of thyreoglobulin<br />
Proteolysis (Thyreoglobulin → T 3 T 4 )<br />
Secretion (T 3 , T 4 )<br />
Trophic effect of TSH: Hyperplasia of the thyroid <strong>gland</strong><br />
(increased vascularisation!)
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