Invasion and metastasis - Experimental Oncology Graduate Study
Invasion and metastasis - Experimental Oncology Graduate Study
Invasion and metastasis - Experimental Oncology Graduate Study
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Step 2 Intravasation: transport thro<br />
vasculature<br />
Hazards:<br />
Anoikis (homelessness)- loss of substrate<br />
contact-triggers apoptosis.<br />
Shear forces.<br />
Lack of stromal support (survival factors).<br />
Exposure to cells of the immune system.<br />
Exposure to platelets (beneficial).