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Lab 15: Population Genetics - eScience Labs

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<strong>Lab</strong> 14: Mendelian <strong>Genetics</strong><br />

Concepts to explore:<br />

Gregor Mendel<br />

Law of segregation<br />

Homozygous<br />

Heterozygous<br />

Independent assortment<br />

Dominant vs. recessive<br />

<br />

<br />

<br />

<br />

<br />

<br />

<br />

Incomplete dominance<br />

Co‐dominance<br />

Genotype<br />

Phenotype<br />

Monohybrid cross<br />

Dihybrid cross<br />

Punnett square<br />

Introduction<br />

In 1866, Gregor Mendel, an Austrian Monk, published a paper entitled “Experiments in plant hybridization”.<br />

It went largely unnoticed until 1900 when it was rediscovered and subsequently became the<br />

basis for what we now refer to as Mendelian <strong>Genetics</strong>.<br />

Mendel was the first to recognize:<br />

<br />

<br />

Inherited characters are determined by specific factors (now recognized these as genes).<br />

These factors occur in pairs (genes).<br />

When both alleles of a gene are the same they are said to be homozygous, while if they are different<br />

they are said to be heterozygous. When gametes form, these factors segregate so that each gamete<br />

contains only one allele for each gene. Remember, alleles reside on the chromosomes that are dividing.<br />

These original observations lead to what we now refer to as The law of segregation and the law of<br />

independent assortment.<br />

Figure 1: Law of Segregation<br />

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