19.06.2015 Views

Lab 15: Population Genetics - eScience Labs

Lab 15: Population Genetics - eScience Labs

Lab 15: Population Genetics - eScience Labs

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

<strong>Lab</strong> <strong>15</strong>: <strong>Population</strong> <strong>Genetics</strong><br />

Questions<br />

1. What observations can you make regarding the gene pool and gene frequency of the founding<br />

individuals?<br />

2. Do these results vary between the populations founded by beakers #1, #2 and #3? Why or<br />

why not?<br />

3. What observations can you make about the genetic variation between the parent and founding<br />

populations?<br />

Experiment 4: Mutations<br />

Many stochastic events change both the gene pool and gene frequencies over time. These parameters<br />

can also change as a result of mutation and natural selection. Mutations are a change in the sequence<br />

of DNA. Most mutations do not change the phenotype and confer no advantages or disadvantages to<br />

the individual. Each of us has hundreds and probably thousands of mutations that do not affect our<br />

fitness.<br />

To answer the assessments for this exercise, assume the following:<br />

<br />

<br />

<br />

There are approximately 3,000,000,000 base pairs in the mammalian genome (genes constitute<br />

only a small portion of this total).<br />

There are approximately 10,000 genes in the mammalian genome.<br />

A single gene averages 10,000 base pairs in size.<br />

167

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!