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Management of Snakebite and Research Management of Snakebite ...

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Features <strong>and</strong><br />

symptoms Myinmu Kyauksae<br />

Clinical Features <strong>of</strong> Russell’s Viper Bite Cases Admitted to Six Township Hospitals ...<br />

Table 2. Local features <strong>and</strong> symptoms <strong>of</strong> Russell’s viper bite cases<br />

Upper Myanmar Lower Myanmar<br />

Taungdwingyi<br />

Danu-phyu Yaekyi<br />

Nyaunglaybin<br />

Bruising % 5 13 27 23 23 6<br />

Necrosis % - 13 10 9 4 6<br />

Blackening % 14 7 - 45 4 6<br />

Epigastric pain % - 55 27 68 23 47<br />

Vomiting % 32 55 4 55 42 67<br />

envenomed cases ranges from 20-26ng/ml (total range 10-50ng/ml) <strong>and</strong> systemic 61-71ng/<br />

ml (total range 20-100ng/ml.) In 54% (37-67%) <strong>of</strong> the systemic envenomed cases, clot<br />

restoration time takes 12hrs-48hrs. Pyrogen reactions are observed in 50%(21-82%) <strong>of</strong> the<br />

antivenom treated cases.<br />

Degree <strong>of</strong><br />

envenoming<br />

Table 3. Degree <strong>of</strong> envenoming <strong>of</strong> the Russell’s viper bite cases*<br />

Myinmu<br />

n=43<br />

Upper Myanmar Lower Myanmar<br />

Kyauksae<br />

n=24<br />

Taungdwingyi<br />

n=134<br />

Danuphyu<br />

n=31<br />

Yaekyi<br />

n=34<br />

Nyaunglaybin<br />

n=28<br />

TOTAL<br />

n=294<br />

Non (%) 9 17 38 29 9 39 28%<br />

Local (%) 72 21 28 13 15 7 29%<br />

Systemic (%) 19 62 34 58 76 54 43%<br />

Systemic +<br />

Compli.(%)**<br />

Venom level<br />

(ng/ml)<br />

Local enven.<br />

Mean (range)<br />

Systemic<br />

enven.<br />

Mean (range)<br />

Clot<br />

restoration<br />

Time >6h%<br />

Pyrogen<br />

reaction %<br />

*1/ 8 47 29 67 54 47 42%<br />

23<br />

(10-45)<br />

64<br />

(50-70)<br />

67<br />

(12-18h)<br />

n=6<br />

24<br />

(10-40)<br />

71<br />

(55-100)<br />

57<br />

(12-48h)<br />

n=14<br />

26<br />

(10-50)<br />

61<br />

(30-100)<br />

37<br />

(12-42h)<br />

n=27<br />

20<br />

(10-40)<br />

20<br />

(10-40)<br />

65.5<br />

(20-100)<br />

n=18<br />

22<br />

(10-30)<br />

22<br />

(10-30)<br />

69<br />

(50-100)<br />

n=20<br />

20<br />

(20-)<br />

64<br />

(30-80)<br />

50<br />

(12-24h)<br />

n=14<br />

22.5<br />

(10-50)<br />

65.7<br />

(20-100)<br />

54%<br />

(12- 48h)<br />

n=99<br />

21 (9/43) 67 (16/24) 50 (22/44) - - 82 (23/28) 50<br />

(70/139)<br />

* number <strong>of</strong> cases<br />

** Calculation based on systemic cases<br />

enven.=envenoming<br />

Compli=complications<br />

Development <strong>of</strong> systemic complications following the bites is shown in Table 4. In<br />

general, systemic bleeding <strong>and</strong> complications are observed in all cases; however, some<br />

features are more common in some localities such as gum bleeding, epistaxis, haemoptysis<br />

37

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