Heparins and mechanical methods for thromboprophylaxis in ...

Analysis 02.02. Comparison 02 Thromboembolic events (TE). LDH vs. placebo, Outcome 02 PEReview: Heparins and mechanical methods for thromboprophylaxis in colorectal surgeryComparison: 02 Thromboembolic events (TE). LDH vs. placeboOutcome: 02 PEStudy LDH Placebo Peto Odds Ratio Weight Peto Odds Ration/N n/N 95% CI (%) 95% CILahnborg 1974 2/11 3/8 100.0 0.39 [ 0.05, 2.91 ]Total (95% CI) 11 8 100.0 0.39 [ 0.05, 2.91 ]Total events: 2 (LDH), 3 (Placebo)Test for heterogeneity: not applicableTest for overall effect z=0.92 p=0.40.1 0.2 0.5 1 2 5 10Favours treatmentFavours controlAnalysis 02.03. Comparison 02 Thromboembolic events (TE). LDH vs. placebo, Outcome 03 DVT and/or PE.Review: Heparins and mechanical methods for thromboprophylaxis in colorectal surgeryComparison: 02 Thromboembolic events (TE). LDH vs. placeboOutcome: 03 DVT and/or PE.Study LDH Placebo Peto Odds Ratio Weight Peto Odds Ration/N n/N 95% CI (%) 95% CICovey 1975 3/9 1/11 12.9 4.22 [ 0.49, 36.09 ]Lahnborg 1974 2/11 3/8 14.7 0.39 [ 0.05, 2.91 ]Negus 1980 0/14 6/19 19.2 0.13 [ 0.02, 0.74 ]Torngren 1978 7/41 11/34 53.2 0.44 [ 0.15, 1.26 ]Total (95% CI) 75 72 100.0 0.46 [ 0.21, 0.98 ]Total events: 12 (LDH), 21 (Placebo)Test for heterogeneity chi-square=6.16 df=3 p=0.10 I² =51.3%Test for overall effect z=2.00 p=0.050.1 0.2 0.5 1 2 5 10Favours treatmentFavours controlHeparins and mechanical methods for thromboprophylaxis in colorectal surgery (Review)Copyright © 2006 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd24