Heparins and mechanical methods for thromboprophylaxis in ...

Analysis 08.01. Comparison 08 Thromboembolic events (TE). LDH vs. LMWH, Outcome 01 DVTReview: Heparins and mechanical methods for thromboprophylaxis in colorectal surgeryComparison: 08 Thromboembolic events (TE). LDH vs. LMWHOutcome: 01 DVTStudy LDH LMWH Peto Odds Ratio Weight Peto Odds Ration/N n/N 95% CI (%) 95% CIKoppenhagen 1992 6/92 6/103 12.1 1.13 [ 0.35, 3.62 ]Mcleod 2001 44/468 44/468 85.8 1.00 [ 0.64, 1.55 ]Onarheim 1986 1/24 1/22 2.1 0.91 [ 0.06, 15.13 ]Total (95% CI) 584 593 100.0 1.01 [ 0.67, 1.52 ]Total events: 51 (LDH), 51 (LMWH)Test for heterogeneity chi-square=0.04 df=2 p=0.98 I² =0.0%Test for overall effect z=0.06 p=10.1 0.2 0.5 1 2 5 10Favours treatmentFavours controlAnalysis 08.02. Comparison 08 Thromboembolic events (TE). LDH vs. LMWH, Outcome 02 PEReview: Heparins and mechanical methods for thromboprophylaxis in colorectal surgeryComparison: 08 Thromboembolic events (TE). LDH vs. LMWHOutcome: 02 PEStudy LDH LMWH Peto Odds Ratio Weight Peto Odds Ration/N n/N 95% CI (%) 95% CIx Fricker 1988 0/2 0/4 0.0 Not estimableMcleod 2001 0/468 1/468 100.0 0.14 [ 0.00, 6.82 ]Total (95% CI) 470 472 100.0 0.14 [ 0.00, 6.82 ]Total events: 0 (LDH), 1 (LMWH)Test for heterogeneity: not applicableTest for overall effect z=1.00 p=0.30.1 0.2 0.5 1 2 5 10Favours treatmentFavours controlHeparins and mechanical methods for thromboprophylaxis in colorectal surgery (Review)Copyright © 2006 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd32