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Replacement FluidsAccessM100PR I S MAReturnReplacement(pre-dilution)Pre-Dilution– Lowers HCT, decreases riskof clotting– UF chemistries do notreflect true plasma soluteconcentrationsEffluent
Replacement FluidsAccessM100PR I S MAReturnReplacement(post-dilution)Post-Dilution– Typically lower replacementsolution rates– May increase anticoagulationneeds– UF chemistries reflect trueplasma solute concentrationsEffluent
Page 1 and 2: CRRT Dose WorkshopWilliam R. Clark,
Page 3 and 4: Dose of Treatment• The concept of
Page 5 and 6: Ultrafiltrationpositive pressureneg
Page 7 and 8: Diffusion vs. ConvectionDiffusion i
Page 9 and 10: AdsorptionMolecular adherence to th
Page 11: Modes of Renal Replacement TherapyP
Page 15: Blood Flow Rate Requirementsin Post
Page 18 and 19: Clearance (mL/min)Solute Equilibrat
Page 20 and 21: Effluent-Based Clearance: Post-Dilu
Page 22 and 23: Effluent-Based Clearance: Pre-Dilut
Page 24 and 25: Effluent-Based Clearance: CVVHDQ E
Page 26 and 27: Effluent-Based Clearance: CVVHDFQ R
Page 28 and 29: CRRT Dose: Urea-Based Versus Efflue
Page 30 and 31: Dose vs Outcome in Post-Dilution CV
Page 32 and 33: Treatment Parameters in Comparative
Page 34 and 35: ATN Trial1164 patients31 sites (24
Page 36 and 37: ATN Study: Characteristics of IHD G
Page 38 and 39: ATN Study: Primary OutcomeVA/NIH Tr
Page 40 and 41: R.E.N.A.L. Trial1508 patients35 sit
Page 42 and 43: Mortality Outcomes in RENAL
Page 44 and 45: Comparison of RENAL with ATNVariabl

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