Exploring the amyloid state of proteins by micro

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Defining <strong>the</strong>Amyloid Pharmacophore
GGVVIA +JugloneMeytal LandauGGVVIA + R-(−)-ApomorphineGGVVIA + 1.2,2′-DihydroxybenzophenoneGGVVIA +CurcuminGGVVIA +Chicago SkyBlueGGVVIA +Phenol RedGGVVIA +BenserazideVQIVYK +RhodamineVQIVYK+PhenolRedVQIVYK +NeocuproineVQIVYK +JugloneVQIVYK +PerphenazineVQIVYK +AZETGGVVIA +EGCGKLVFFA +ThTVQIVYK +Phenol RedAbeta17-40+ FDDNPVQIVYK +ThTGVVEVD +Orange GVQIVYK +MethyleneBlueSSTNVG +Phenol redVQIVYK +Azure CVQIVYK +MeclocyclinesulfosalicylateVQIVYK + 1,2-NaphthoquinoneVQIVYK+RhodamineVQIVYK+Hexadecyltrimethylammonium bromideVQIVYK+ApomorphineVQIVYK +RolitetracyclineGGVVIA+ThTGGVVIA +RhodamineGGVVIA +Rifamycin SVGGVVIA + 1,2-NaphthoquinoneSSTNVG+Phenol RedVQIVYK +Chicago skyblue 6BVQIVYK+DobutamineGGVVIA+Chicago SkyBlueGGVVIA +Orange GGGVVIA+Azure CGGVVIA +Trimethyl(tetradecyl)ammoniumbromideGGVVIA + CreosolGGVVIA +Eosin YVQIVYK+FDDNP
Page 1 and 2: The Amyloid State of Proteinsand Mi
Page 3 and 4: Amyloid• Unbranched, elongated pr
Page 5 and 6: My Scientific Dilemma in 2001Import
Page 7 and 8: 10-100 mM < 24 hrGNNQQNY microcryst
Page 9 and 10: Packing of GNNQQNY peptides in micr
Page 11 and 12: Microfocus is required to reducebac
Page 13 and 14: GNNQQNY, a dry steric zipperFibers
Page 15 and 16: As of April 2011, ~90 X-raycrystal
Page 17: D-TLKIVW prevents fibril formation
Page 21 and 22: Structure of KLVFFA with Orange GKL
Page 23 and 24: Amyloid-like crystalsof KLIMY from
Page 25 and 26: Nano-crystals oflonger (11-residue)
Page 27 and 28: 10 micron Mictigen micromesh in cry
Page 29 and 30: Drosophila crystal cellon 10 µm me
Page 31 and 32: Cell Types Containing Intracellular
Page 33 and 34: The Amyloid State of ProteinsUCLA:

Exploring the amyloid state of proteins by micro

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