Biomarkers of High Grade Dysplasia in Barrett's Esophagus
Biomarkers of High Grade Dysplasia in Barrett's Esophagus
Biomarkers of High Grade Dysplasia in Barrett's Esophagus
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Grad<strong>in</strong>g <strong>Dysplasia</strong> <strong>in</strong> BEFeature Negative IND LGD HGDSurface + + - -maturationArchitecture Normal Normal or mild Mild alteration Marked alterationalterationCytology Normal or Mild alterations or Mild alterations (D) Marked alteration;reactive focal marked with or marked (F); loss <strong>of</strong> polarity<strong>in</strong>flammation ma<strong>in</strong>ta<strong>in</strong>ed polarity(Montgomery et al Human Pathology 2001)
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