Biomarkers of High Grade Dysplasia in Barrett's Esophagus

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LGD
Page 1: Biomarkers of High GradeDysplasia i
Page 7: Barrett’s Esophagus• 5-15% of a
Page 12 and 13: Barrett’s Esophagus SequelaeUlcer
Page 14 and 15: Histopathologic Dx of DysplasiaDysp
Page 16 and 17: Dysplasia in Barrett’s Esophagus
Page 20 and 21: Surveillance GuidelinesInitial scre
Page 22 and 23: Barrett’s Related DysplasiaIntero
Page 24 and 25: ObjectivesIdentify differentially e
Page 26 and 27: Methods (1)• Esophageal biopsies
Page 28 and 29: Methods (2)• RNA Extraction/Prepa
Page 30 and 31: Biopsy of HGD
Page 32 and 33: Laser Capture MicrodissectionBarret
Page 34 and 35: Results132 genes with 2.5 > increas
Page 37 and 38: Table 2. Differentially Expressed G
Page 39 and 40: Protein Expression Confirmed by Imm
Page 41 and 42: Lipocalin-2
Page 43 and 44: Trefoil factor 1
Page 45 and 46: Next Steps……1. Continue testing
Page 47: Molecular Pathology CoreRonald DeLe

Biomarkers of High Grade Dysplasia in Barrett's Esophagus

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