Infectiologic differential diagnosis of chronic Lyme disease and so ...

More documents

Recommendations

Info

Table 7 Laboratory diagnostics for bartonellosis - Blood smear - Serology - Pathogen detection using culture methods - Pathogen detection using PCR - Histopathological investigations In cases of infection with Bartonella, the blood smear initially shows pathogens on the outer membrane; in the further course the pathogens are increasingly localized intracellularly. In the process, the light colored center of the erythrocytes is lost (Fig. 1). A. B. 10
11 Fig. 1. Erythrocytes infected with Bartonella henselae (Bh). A. Early stage, Bh on the outside of the erythrocytes; b. With increasing duration of infection, Bh primarily intracellular; erythrocytes loose their lightcolored center. There is no information on the value of serology in the literature. In particular, the question as to whether seronegativity rules out the disease has not been clarified. On the other hand, as is the case for many other infectious diseases, a positive serological finding merely proves that an infection took place, but does not indicate that the disease currently exists. Detecting Bartonella in culture is extremely problematical, and the sensitivity is very low so that this method of investigation is not part of routine diagnostics. Detection of pathogens using PCR in biopsies appears to be very promising [87, 232], but the investigation with PCR must follow the biopsy nearly immediately [88]. The chronic course of bartonellosis has been described in numerous studies, in part, on large groups [90 - 94]. The long duration of the disease, which frequently covers many years, and the high similarity of the disease manifestations makes it extremely difficult to distinguish from chronic Lyme disease. Thus, bartonellosis is of great importance in the infectiologic differential diagnosis of Lyme disease. In this context, attention should be paid to the fact that B. henselae has been found in ticks and that the transmission of B. henselae by ticks has been documented by means of pathogen detection in the liquor [95]. Additionally, the prevalence of B. henselae in ticks is apparently high; scientific studies determined a prevalence of 40% [96]. According to my own surveys, 78% of the patients with chronic Lyme disease proved to be seropositive for Bartonella henselae.
Page 1 and 2: Infectiologic differential diagnosi
Page 3 and 4: 3 Anamnistically, one has to consid
Page 5 and 6: Table 2 LD coinfections (not tick-b
Page 7 and 8: Table 5 Bartonellosis’ infection
Page 9: Table 6 Main disease manifestations
Page 13 and 14: 13 Bartonellae are localized in ery
Page 15 and 16: ESR und CRP elevated Hypercalcemia
Page 18 and 19: Table 9 Antibiotic treatment of bar
Page 20 and 21: antibiosis is that the antibiotic i
Page 22 and 23: The laboratory diagnostics for Chla
Page 24 and 25: The arthritis occurs in 1% of the u
Page 26 and 27: In the differential diagnosis of Ly
Page 28 and 29: Late phase: - Reactive arthritis -
Page 30 and 31: the depiction of chronic yersiniosi
Page 32 and 33: In Yersinia-PCR-positive patients,
Page 34 and 35: - Incubation period 3 weeks - Atypi
Page 36 and 37: system, of the skin and other organ
Page 38 and 39: - Ehrlichia chaffeensis [1] - Anapl
Page 40 and 41: Since seroprevalence merely express
Page 42 and 43: B. microti is the predominant patho
Page 44 and 45: epresent a major health hazard and
Page 46 and 47: The decisive diagnostic information
Page 48 and 49: Probable: IFA IgG 1:1024 and one of
Page 50 and 51: The main manifestation of the Campy
Page 52 and 53: The term “reactive arthritis” i
Page 54 and 55: In the diagnosis of a “reactive a
Page 56 and 57: Table 27 Disease manifestations of
Page 58 and 59: addition, other pathogens discussed
Page 60 and 61:
[8] Schouls LM, Van De Pol I, Rijpk
Page 62 and 63:
[25] Hermanowska-Szpakowicz T, Skot
Page 64 and 65:
[43] Bakken JS, Krueth JK, Lund T,
Page 66 and 67:
[60] Fox LM, Wingerter S, Ahmed A e
Page 68 and 69:
[80] Marra CM. Neurologic complicat
Page 70 and 71:
[100] Pulliainen AT, Dehio C. Barto
Page 72 and 73:
[118] Bass JW, Freitas BC, Freitas
Page 74 and 75:
[137] Gaydos CA, Roblin PM, Hammers
Page 76 and 77:
[155] Cover TL, Aber RC. Yersinia e
Page 78 and 79:
multi-organ donors for the presence
Page 80 and 81:
[190] Straubinger RK, Straubinger A
Page 82 and 83:
[208] Bitnun A, Ford-Jones E, Blase
Page 84 and 85:
patients with reactive and undiffer
Page 86 and 87:
[242] Appelbaum PC, Gillespie SH, B
Page 88 and 89:
pneumoniae infection associated wit
Page 90 and 91:
[276] Thomas NH, Collins JE, Robb S
Page 92 and 93:
[294] File TM Jr, Segreti J, Dunbar
Page 94 and 95:
[310] Sorvillo FJ, Lieb LE, Waterma
Page 96 and 97:
henselae Isolates Collected from Ca
Page 98 and 99:
[345] Raoult D, Levy PY, Harlé JR,
show all

Infectiologic differential diagnosis of chronic Lyme disease and so ...

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?