Infectiologic differential diagnosis of chronic Lyme disease and so ...
Infectiologic differential diagnosis of chronic Lyme disease and so ...
Infectiologic differential diagnosis of chronic Lyme disease and so ...
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system, <strong>of</strong> the skin <strong>and</strong> other organs [265], macula edema [270], bilateral uveitis<br />
[291], nephritis [292], arthritis, hepatitis, pericarditis [292].<br />
The laboratory diagnostics for Mycoplasma pneumoniae is presented in Table 20.<br />
The serology only becomes positive after several weeks, as is the case for most<br />
infectious <strong>disease</strong>s. It is therefore significant for the <strong>chronic</strong> <strong>disease</strong> course.<br />
Seropositivity substantiates the infection, but not the <strong>disease</strong>. Whether a <strong>chronic</strong><br />
infection can al<strong>so</strong> exist in cases <strong>of</strong> seronegativity has not yet been scientifically<br />
clarified.<br />
The LTT for Mycoplasma pneumoniae has not been validated by studies.<br />
Pathogen detection, e.g. in articular effusion is possible, but it is difficult, has a low<br />
sensitivity <strong>and</strong> is therefore not part <strong>of</strong> routine diagnostics.<br />
Table 20<br />
Laboratory diagnostics for Mycoplasma pneumoniae infection<br />
Serology<br />
LTT<br />
Pathogen detection<br />
� PCR<br />
� Culture<br />
The antibiotic treatment <strong>of</strong> Mycoplasma pneumoniae is presented in Table 21. The<br />
drugs <strong>of</strong> choice are azithormycin [293] und lev<strong>of</strong>loxacin [294].<br />
Table 21<br />
Antibiotic treatment <strong>of</strong> Mycoplasma pneumoniae infection<br />
Antibiotic Dose / Day<br />
Azithormycin 500 mg<br />
Lev<strong>of</strong>loxacin 500 mg<br />
Doxycycline 400 mg<br />
36
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