Cover Introduction ProSure Clinical Studies ... - Abbott Nutrition

Supplemental drinks enriched with omega-3 fatty acids improve nutritional statusand quality of life in lung cancer patientsCovervan der Meij BS, Languis JA, Zadelaar SM, Spreeuwenberg MD, von Blomberg ME, Paul MA, Smit EF, van Leeuwen PAJPEN J Parenter Enteral Nutr. 2009;33:207IntroductionProSureClinical StudiesSupportingPublicationsvan der Meij and colleagues conducted a double-blind, randomized,placebo-controlled trial in patients with stage III non-small cell lungcarcinoma who were randomized to receive either ProSure or acontrol supplement during 5 weeks of chemo-radiotherapy.ObjectiveTo compare the effects on nutritional status, quality of life, physicalactivity and immune parameters of a supplemental drink enriched withomega-3 fatty acids with a placebo supplemental drink in patientswith non-small cell lung cancer receiving chemo-radiotherapy.Study Design• Study Population: Patients with stage III non-small cell lungcarcinoma receiving chemo-radiotherapy (n = 40; ProSure = 20,control = 20)• length of Study: 5 weeks• Intervention: 2 servings ProSure (240 mL/ serving) or isocaloricisonitrogenous controlOutcomes• Compared to the control group, the ProSure group had betterweight maintenance during weeks 1 2, and 4 (1.1 kg, 1.4 kg, and1.7 kg, P < 0.05) and higher physical functioning as measured byEORTC-QLQ-C30 and physical activity measured by wearing thePersonal Activity Monitor at weeks 3 and 5 (P < 0.05).Study ConclusionsResults of this study suggest beneficial effects of a high-protein,calorically-dense, low-fat nutritional supplement enriched with EPA(ProSure) on nutritional status, physical activity and quality of life,but not on immune parameters in patients with non-small cell lungcarcinoma undergoing chemo-radiotherapy.EPA -eicosapentaenoic acid