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Core facilities at EMBL – an overview - Molmedrex Project

Core facilities at EMBL – an overview - Molmedrex Project

Core facilities at EMBL – an overview - Molmedrex Project

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Applic<strong>at</strong>ions <strong>at</strong> <strong>EMBL</strong>• Whole-genome <strong>an</strong>alyses of tr<strong>an</strong>scriptome,miRNome & occup<strong>an</strong>cy profiling• Identific<strong>at</strong>ion of DNA <strong>an</strong>d RNA protein binding sites(ChIP-Seq, CLIP-Seq)• Identific<strong>at</strong>ion of methyl<strong>at</strong>ion p<strong>at</strong>terns (Methyl-Seq)• Identific<strong>at</strong>ion of small ncRNA (miRNA) sequences• Digital gene expression profiling (RNA-Seq)• Whole genome sequencing• De novo sequencing <strong>an</strong>d re-sequencing (pairedendedreads)• Structural vari<strong>at</strong>ion of genomes – CNV, SNP, in/del

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