Drugs of abuse and tranquilizers in Dutch surface waters, drinking ...

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RIVM Report 703719064ContentsAcknowledgements—7Summary—111 Introduction—152 Methods and materials—172.1 Selection of sampling locations—172.2 Selection of compounds—172.3 Sample collection—212.4 Analytical methods—212.4.1 Identification and confirmation—222.4.2 Limit of quantification—223 Results and discussion—253.1 Surface waters and drinking water—253.1.1 DOA in the drinking water treatment chain—263.2 Wastewater—343.3 Estimated loads of DOA based on monitoring data—363.3.1 Loads through the Rhine and Meuse rivers—363.3.2 Loads through STPs—373.3.3 Estimated cocaine consumption of the population—393.4 Comparing results of the three laboratories—393.5 Comparing Dutch monitoring results with other countries—403.6 Provisional drinking water limits for DOA—424 Conclusions and recommendations—454.1 Conclusions—454.2 Recommendations—47References—49Appendix A UHPLC-MS/MS at UJI—53Appendix B HPLC-MS/MS at RIVM—57Appendix C HPLC-LTQ-Orbitrap MS at KWR—65Appendix D HPLC-MS/MS at UA—69Appendix E Monitoring results surface waters and drinking water - 71Appendix F Monitoring results for wastewater—75Appendix G Cocaine load back-calculation method—79Appendix H Provisional drinking water limits—81Page 9 of 90
RIVM Report 703719064Page 10 of 90
Page 1: ugs ofbuse andDrugs of abuse and tr
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Page 13 and 14: RIVM Report 703719064 Urban wastewa
Page 15 and 16: RIVM Report 703719064As this first
Page 17 and 18: RIVM Report 7037190642. to evaluate
Page 19 and 20: RIVM Report 703719064Results of a p
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Page 23 and 24: RIVM Report 703719064The addition o
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Page 27 and 28: RIVM Report 7037190643.1.1 DOA in t
Page 29 and 30: RIVM Report 703719064Andijk70ng/l60
Page 31 and 32: RIVM Report 703719064At Weesperkars
Page 33 and 34: RIVM Report 703719064Ouddorp70ng/l6
Page 35 and 36: RIVM Report 703719064Bankfiltrate70
Page 37 and 38: RIVM Report 7037190643.3 Estimated
Page 39 and 40: RIVM Report 703719064further resear
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Page 45 and 46: RIVM Report 703719064concentration
Page 47 and 48: RIVM Report 703719064Barbiturates a
Page 49 and 50: RIVM Report 703719064Further resear
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RIVM Report 703719064Quality contro
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RIVM Report 703719064Table B.2. Res
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RIVM Report 703719064Table B.2. Res
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RIVM Report 703719064Appendix C HPL
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RIVM Report 703719064Table C.3 pres
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RIVM Report 703719064Appendix D HPL
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RIVM Report 703719064Appendix E Mon
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RIVM Report 703719064LEGEND - below
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RIVM Report 703719064Appendix F Mon
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RIVM Report 703719064Chemical class
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RIVM Report 703719064Appendix G Coc
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RIVM Report 703719064Appendix H Pro
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RIVM Report 703719064haemodynamic c
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RIVM Report 703719064carcinogenicit
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RIVM Report 703719064provisional dr
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RIVM Report 703719064ReferencesAmio
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N.G.F.M. van der Aa | E. Dijkman |
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