Molecular Biology Databases - CNB - Protein Design Group

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GENE ONTOLOGYAnnotators•Database curators•Gene Ontology Annotation (GOA) database: central repository, applies-this controlled vocabulary to a non-redundant set of proteinsGO browsers• Search GO terms for a gene/protein• Retrieve genes/proteins associated to a GO term
GenBank and EMBL● GenBank and the EMBL nucleotide databases were founded in 1986.● Contain ALL DNA sequences ever published .● Submissions are made by the laboratories or centers that obtain them.● Depositing sequences in GenBank / EMBL is a requisite of most journalsto accept manuscripts in which new sequences are reported.● In August 2003 they contained:● 18,197.000 sequence files● 22.617,000.000 nucleotides● Every two months a new complete version of the database is published.
Page 1 and 2: MOLECULAR BIOLOGYDATABASESJuan Carl
Page 3 and 4: Ouellette, 2000
Page 5 and 6: GROWING NUMBER OF DATABASESThe numb
Page 7 and 8: HOW TO ACCESS DATABASESDatabases ar
Page 9 and 10: CONTENT OF PRIMARY DATABASESExperim
Page 11 and 12: CLASSIFICATION OF MOLECULARBIOLOGY
Page 13 and 14: DATABASE SEARCHES:QUERY TYPESTEXT Q
Page 15 and 16: DATABASE SEARCHES:QUERY TYPESQUERIE
Page 17 and 18: NUCLEOTIDE DATABASESGenBank• Main
Page 19 and 20: GENOME DATABASESEnsemblEnsembl, EBI
Page 21 and 22: GENOME DATABASESEntrez Genome• In
Page 23 and 24: GENE-CENTERED DATABASESComplete inf
Page 25 and 26: PROTEIN DATABASESNon-redundant data
Page 27 and 28: PROTEIN DATABASESUniProtKB/Swiss-Pr
Page 29 and 30: STRUCTURE DATABASESProtein Data Ban
Page 31 and 32: PROTEIN DOMAINS DATABASESProtein do
Page 33 and 34: GENE EXPRESSION DATABASESGene expre
Page 35 and 36: PATHWAY DATABASESDisplay metabolic
Page 37 and 38: ONTOLOGIES IN MOLECULAR BIOLOGYCont
Page 39: GENE ONTOLOGYDeveloped and maintain
Page 43 and 44: • Entrez is the indexing and data
Page 45 and 46: MAIN DATABASESACCESIBLE WITH ENTREZ
Page 47: FASTA format> essentialGIAccession.
Page 50 and 51: GBFF: FEATURESFEATURESLocation/Qual
Page 52 and 53: EMBL AND SwissProt FORMATThe field
Page 54 and 55: EMBL AND SwissProt FORMATFT source
Page 58 and 59: • Sequence Retrieval System is a
Page 60: ACKNOWLEDGMENTSThis presentation co

Molecular Biology Databases - CNB - Protein Design Group

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