Pro-oxidant activity of vitamin C in drinking water ... - Ãbo Akademi

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ReferencesREFERENCES1. Arrigoni O, De Tullio MC. Ascorbic acid: Much more than just an antioxidant. BiochimBiophys Acta. 2002;1569:1-92. Naidu KA. Vitamin C in human health and disease is still a mystery? An overview. Nutr J.2003;2:73. D'Agostini F, Izzotti A, Balansky RM, Bennicelli C, De Flora S. Modulation of apoptosisby cancer chemopreventive agents. Mutat Res. 2005;591:173-1864. Schneider JE, Browning MM, Floyd RA. Ascorbate/iron mediation of hydroxyl free radicaldamage to P322 plasmid DNA. Free Radic Biol Med. 1988;5:287-2955. Buettner GR, Jurkiewicz BA. Catalytic metals, ascorbate and free radicals: Combinations toavoid. Radiat Res. 1996;145:532-5416. Halliwell B. Vitamin C: Antioxidant or pro-oxidant in vivo? Free Radic Res. 1996;25:439-4547. Podmore ID, Griffiths HR, Herbert KE, Mistry N, Mistry P, Lunec J. Vitamin C exhibitspro-oxidant properties. Nature. 1998;392:5598. Carr AC, Frei B. Toward a new recommended dietary allowance for vitamin C based onantioxidant and health effects in humans. Am J Clin Nutr. 1999;69:1086-11079. Carr A, Frei B. Does vitamin C act as a pro-oxidant under physiological conditions? Faseb J.1999;13:1007-102410. Hathcock JN, Azzi A, Blumberg J, Bray T, Dickinson A, Frei B, Jialal I, Johnston CS, KellyFJ, Kraemer K, Packer L, Parthasarathy S, Sies H, Traber MG. Vitamins E and C are safeacross a broad range of intakes. Am J Clin Nutr. 2005;81:736-74511. Rivers JM. Safety of high-level vitamin C ingestion. Int J Vitam Nutr Res Suppl. 1989;30:95-10212. Goldman HM, Gould BS, Munro HN. The antiscorbutic action of L-ascorbic acid and D-isoascorbic acid (erythorbic acid) in the guinea pig. Am J Clin Nutr. 1981;34:24-3313. Pimentel L. Scurvy: Historical review and current diagnostic approach. Am J Emerg Med.2003;21:328-33214. Jacob RA. Three eras of vitamin C discovery. Subcell Biochem. 1996;25:1-1615. Manchester KL. An orange a day keeps the scurvy away. Trends Pharmacol Sci. 1998;19:167-17016. Oeffinger KC. Scurvy: More than historical relevance. Am Fam Physician. 1993;48:609-61317. Szent-Gyorgyi A. Observation of the functions of peroxidase systems and the chemistry ofthe adrenal cortex. Biochem J. 1928;22:1387-140949
References18. Svirbely J, Szent-Gyorgyi A. The chemical nature of vitamin C. The Biochemical Journal.1932;26:865-87019. Stone N, Meister A. Function of ascorbic acid in the conversion of proline to collagenhydroxyproline. Nature. 1962;194:555–55720. Levine M. New concepts in the biology and biochemistry of ascorbic acid. N Engl J Med.1986;314:892-90221. Kallner AB, Hartmann D, Hornig DH. On the requirements of ascorbic acid in man:Steady-state turnover and body pool in smokers. Am J Clin Nutr. 1981;34:1347-135522. Hornig D. Metabolism and requirements of ascorbic acid in man. S Afr Med J. 1981;60:818-82323. Johnston CS. Biomarkers for establishing a tolerable upper intake level for vitamin C. NutrRev. 1999;57:71-7724. Pauling L. Are recommended daily allowances for vitamin C adequate? Proc Natl Acad Sci US A. 1974;71:4442-444625. Pauling L. Vitamin C therapy of advanced cancer. N Engl J Med. 1980;302:694-69526. Moertel CG, Fleming TR, Creagan ET, Rubin J, O'Connell MJ, Ames MM. High-dosevitamin C versus placebo in the treatment of patients with advanced cancer who have hadno prior chemotherapy. A randomized double-blind comparison. N Engl J Med.1985;312:137-14127. Pauling L, Herman ZS. Criteria for the validity of clinical trials of treatments of cohorts ofcancer patients based on the Hardin Jones principle. Proc Natl Acad Sci U S A.1989;86:6835-683728. Hemila H. Vitamin C supplementation and common cold symptoms: Factors affecting themagnitude of the benefit. Med Hypotheses. 1999;52:171-17829. Douglas RM, Hemila H, D'Souza R, Chalker EB, Treacy B. Vitamin C for preventing andtreating the common cold. Cochrane Database Syst Rev. 2004:CD00098030. Douglas RM, Hemila H. Vitamin C for preventing and treating the common cold. PLoSMed. 2005;2:e168; quiz e21731. Machefer G, Groussard C, Rannou-Bekono F, Zouhal H, Faure H, Vincent S, Cillard J,Gratas-Delamarche A. Extreme running competition decreases blood antioxidant defensecapacity. J Am Coll Nutr. 2004;23:358-36432. Stahl W, Sies H. Antioxidant defense: Vitamins E and C and carotenoids. Diabetes. 1997;46Suppl 2:S14-1833. Frei B. On the role of vitamin C and other antioxidants in atherogenesis and vasculardysfunction. Proc Soc Exp Biol Med. 1999;222:196-20450
Page 1 and 2:
Pro-oxidant activity of vitamin C i
Page 3 and 4:
Supervised byDocent Tommy Nordströ
Page 5 and 6: ContentsCONTENTSLIST OF ORIGINAL PU
Page 8 and 9: List of original publicationsLIST O
Page 10 and 11: AcknowledgementsACKNOWLEDGEMENTSThi
Page 12 and 13: AbbreviationsABBREVIATIONSAsc …
Page 14 and 15: Review of the literatureREVIEW OF T
Page 16 and 17: Review of the literatureSince vitam
Page 18 and 19: Review of the literaturestill added
Page 20 and 21: Review of the literatureantioxidant
Page 22 and 23: Review of the literatureThe α-toco
Page 24 and 25: Review of the literatureCopper, wil
Page 26 and 27: Review of the literatureOH • + H
Page 28 and 29: Review of the literatureFormation o
Page 30 and 31: Review of the literature3.2. The ro
Page 32 and 33: Review of the literaturecopper conc
Page 34 and 35: Experimental proceduresEXPERIMENTAL
Page 36 and 37: Experimental procedures2.2. Measure
Page 38 and 39: Experimental procedurestetrahydrate
Page 40 and 41: ResultsRESULTS1. Vitamin C induces
Page 42 and 43: Results3. Oxidative decomposition o
Page 44 and 45: Resultsdifferent water samples vari
Page 46 and 47: DiscussionDISCUSSIONNowadays, ascor
Page 48 and 49: DiscussionCu 2+ + Asc → Cu + + As
Page 50 and 51: Discussion3. Iron inhibits vitamin
Page 52 and 53: Discussionperoxide might have an im
Page 54 and 55: ConclusionsCONCLUSIONSThe main focu
Page 58 and 59: References34. Padayatty SJ, Katz A,
Page 60 and 61: References66. Sies H, Stahl W, Sund
Page 62 and 63: References95. Halliwell B. Role of
Page 64 and 65: References127. Park S, Han SS, Park
Page 66 and 67: References157. Critchley MM, Cromar
Page 68 and 69: References185. Liao CH, Kang SF, Wu
Page 70 and 71: References214. Orr CW. Studies on a
Page 72: References243. Miller C, Kennington
Page 88 and 89: Free Radical Research, Volume 38 Nu
Page 90 and 91: VITAMIN C OXIDATION IN DRINKING WAT
Page 92 and 93: VITAMIN C OXIDATION IN DRINKING WAT
Page 94 and 95: Free Radical Research, May 2005; 39
Page 96 and 97: Iron inhibits Vitamin C/copper-indu
Page 98 and 99: Iron inhibits Vitamin C/copper-indu
Page 100 and 101: Free Radical Research, November 200
Page 102 and 103: Hydrogen peroxide formation in drin
Page 104 and 105: Hydrogen peroxide formation in drin
Page 106 and 107:
Hydrogen peroxide formation in drin
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