Professional Panel Screen by LC/MS/MS

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Calibrator Mix: <strong>Professional</strong> <strong>Panel</strong>Ketamine 100 ng/mLMeperidine 300 ng/mLTramadol 300 ng/mLPentazocine 25 ng/mLButorphanol 25 ng/mLMeperidine-D4 IS300 ng/mL
LOQ Control
Page 1 and 2: Professional Panel Screen byLC/MS/M
Page 3 and 4: 1200L LC/MS & LC/MS/MSProStar Binar
Page 5 and 6: MRM Scanning of m/z Parent >Daughte
Page 7 and 8: Specimen Preparation for LC/MS/MS R
Page 9 and 10: LC/MS/MS for Screening?Advantages:1
Page 11 and 12: Tramadol with 246.0 m/z qualifier24
Page 13 and 14: Other Advantages of LC/MS/MS• Rap
Page 15 and 16: Ion Guides (Q1 and Q3)Pre-ion guide
Page 17 and 18: Collision Cell: Curved DesignIonSou
Page 19 and 20: 1200L LC/MSElectrospray Ionization
Page 21 and 22: Off-axis Spray NeedleOff-axis orien
Page 23 and 24: Adjustable NebulizationLiquidNebuli
Page 25 and 26: Fully Adjustable SprayNeedleX-Adjus
Page 27 and 28: Desolvation andDeclusteringGasHeate
Page 29 and 30: Wide Bore, Metal CapillaryGasHeater
Page 31 and 32: ELECTROSPRAY IONIZATION (ESI)Mandat
Page 33 and 34: For ESI need low ionic strengths of
Page 35 and 36: Chromatogram Plots
Page 37 and 38: - 25 % Control
Page 39: Butorphanol (25 ng/mL cutoff)
Page 43 and 44: Typical Negative Screen
Page 45 and 46: Butorphanol +/- 25% ControlsLCMSMS
Page 47 and 48: 450400350300250200150100Meperidine
Page 49 and 50: 450400350300250200150100Meperidine
Page 51 and 52: Pentazocine +/- 25% ControlsLCMSMS
Page 53 and 54: 450400350300250200150100Tramadol +/
Page 55 and 56: Composite Precision: Professional P

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