Professional Panel Screen by LC/MS/MS
Professional Panel Screen by LC/MS/MS
Professional Panel Screen by LC/MS/MS
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<strong>LC</strong>/<strong>MS</strong>/<strong>MS</strong> for <strong>Screen</strong>ing?Advantages:1. No need to derivitize, , faster processing for multipleanalytes.2. Can screen more analytes with a single simple, rapidextraction.3. More specific, even at peaks appearing at same retentiontimes (RT).4. Higher sensitivity, no need to dry down SPE eluates.Disadvantages:1. Same MW parents generally need RT separation, e.g.,morphine / hydromorphone, and codeine / hydrocodone.2. Generally limited to a multiple screen of @ 10 analytes for“rapid” <strong>LC</strong>/<strong>MS</strong>/<strong>MS</strong> screening runs of @ 1min.
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