Professional Panel Screen by LC/MS/MS

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Analyzer ComponentsQ1Multiplier+/- 5kV postaccelerationQ3Q2Curved186 mmPath
MRM Scanning of m/z Parent >Daughter mass fragmentsAnalyte Parent > Daughter RTCollision EnergyMeperidine-D4: 252.3 > 224.0 0.483 min -18.5 VoltsKetamine: 238.2 > 125.0 0.434 min -24.5 VoltsPentazocine: 286.5 > 218.0 0.524 min -17.5 VoltsButorphanol: 328.4 > 310.0 0.497 min -19.5 VoltsMeperidine:248.2 > 220.0 0.484 min -18.5 VoltsTramadol: 264.2 > 58.00.459 min -10.5 Volts264.2 > 246.0 0.459 min -09.0 Volts
Page 1 and 2: Professional Panel Screen byLC/MS/M
Page 3: 1200L LC/MS & LC/MS/MSProStar Binar
Page 7 and 8: Specimen Preparation for LC/MS/MS R
Page 9 and 10: LC/MS/MS for Screening?Advantages:1
Page 11 and 12: Tramadol with 246.0 m/z qualifier24
Page 13 and 14: Other Advantages of LC/MS/MS• Rap
Page 15 and 16: Ion Guides (Q1 and Q3)Pre-ion guide
Page 17 and 18: Collision Cell: Curved DesignIonSou
Page 19 and 20: 1200L LC/MSElectrospray Ionization
Page 21 and 22: Off-axis Spray NeedleOff-axis orien
Page 23 and 24: Adjustable NebulizationLiquidNebuli
Page 25 and 26: Fully Adjustable SprayNeedleX-Adjus
Page 27 and 28: Desolvation andDeclusteringGasHeate
Page 29 and 30: Wide Bore, Metal CapillaryGasHeater
Page 31 and 32: ELECTROSPRAY IONIZATION (ESI)Mandat
Page 33 and 34: For ESI need low ionic strengths of
Page 35 and 36: Chromatogram Plots
Page 37 and 38: - 25 % Control
Page 39 and 40: Butorphanol (25 ng/mL cutoff)
Page 41 and 42: LOQ Control
Page 43 and 44: Typical Negative Screen
Page 45 and 46: Butorphanol +/- 25% ControlsLCMSMS
Page 47 and 48: 450400350300250200150100Meperidine
Page 49 and 50: 450400350300250200150100Meperidine
Page 51 and 52: Pentazocine +/- 25% ControlsLCMSMS
Page 53 and 54: 450400350300250200150100Tramadol +/
Page 55 and 56:
Composite Precision: Professional P
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Professional Panel Screen by LC/MS/MS

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