Research on Essence of Chicken - Mahidol University
Research on Essence of Chicken - Mahidol University
Research on Essence of Chicken - Mahidol University
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Effect <strong>of</strong> four doses <strong>of</strong> carnosine <strong>on</strong> posttetanicand l<strong>on</strong>g-term potentiati<strong>on</strong> <strong>of</strong>dentate gyrus. Top panel: inserts <strong>of</strong>grand averaged raw data (ten waveformsfor each rat) at three different timewindows (Baseline: prior to the first HFS;post-HFS: after the last HFS; andEndExp: prior to the end <strong>of</strong> theexperiment) in c<strong>on</strong>trol and four differentcarnosine (car) doses (in lg/lL).Calibrati<strong>on</strong> bars: 5 ms and 4 mV. Middlepanel: Time course <strong>of</strong> populati<strong>on</strong> spikeamplitude (left) and excitatorypostsynaptic potential slope (right)recorded in dentate gyrus in resp<strong>on</strong>se tomedial perforant pathway stimulati<strong>on</strong>.x axis: time (min) and y axis: percent <strong>of</strong>baseline activity. Each plot representsmean values <strong>of</strong> carnosine-infused rats indoses <strong>of</strong> 0.1 lg/lL (black square), 1 lg/lL(black triangle), 10 lg/lL (cross), or 100lg/lL (star) and aCSF-infused rats (blackdiam<strong>on</strong>d) in the 2 min before HFSprotocol. Horiz<strong>on</strong>tal bar: timing <strong>of</strong>infusi<strong>on</strong> Bottom panel: Bars are shownas mean + SEM <strong>of</strong> each experimentalgroup in the four time windows(baseline, post-tetanic, inducti<strong>on</strong> andmaintenance phases).Effect <strong>of</strong> four doses <strong>of</strong> carnosine<strong>on</strong> baseline synaptic activity <strong>of</strong>dentate gyrus in resp<strong>on</strong>se to teststimuli. Time course <strong>of</strong> excitatorypostsynaptic potential slope(EPSP, left) and populati<strong>on</strong> spikeamplitude (PS, right) recorded indentate gyrus in resp<strong>on</strong>se tomedial perforant pathwaystimulati<strong>on</strong> with test stimuli. x axis:time (min) and y axis: percent <strong>of</strong>baseline activity. Each pointrepresents mean values <strong>of</strong>carnosine-infused rats (n = 4 foreach group) in doses <strong>of</strong> 0.1 lg/lL(square), 1 lg/lL (triangle); 10 lg/lL(cross), or 100 lg/lL (star) andaCSF-infused rats (diam<strong>on</strong>d) inthe 2 min before HFS protocol.‘inf’ bar: timing <strong>of</strong> infusi<strong>on</strong>.Effects <strong>of</strong> Drinking <strong>of</strong> the <strong>Essence</strong> <strong>of</strong> <strong>Chicken</strong><strong>on</strong> Horm<strong>on</strong>al Levels in Normal Human VolunteersChittin Chindadoungratana, Naiphinich Kotchabhakdi,and William G.A. L<strong>on</strong>gworthNeuro-Behavioural Biology Center,Institute <strong>of</strong> Science and Technology for <str<strong>on</strong>g>Research</str<strong>on</strong>g>and Development, <strong>Mahidol</strong> <strong>University</strong>, Salaya,Nakornpathom 73170 Thailand.Email: scnkc@mahidol.ac.thCopyright 2000 by N.Kotchabhakdi et al & <strong>Mahidol</strong>-Cerebos Collaborative <str<strong>on</strong>g>Research</str<strong>on</strong>g> Project
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