Names for MNS Blood Group Alleles

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Names for MNS blood group alleles v2.0 110914Table 1. MNS alleles with single nucleotide polymorphisms that generate blood group antigens.A. GYPA: Reference allele MNS*01 encodes M, En a , ENEH, ENEP, ENAV, ENDA, ENEV.Note: In most cases, the nucleotide changes also can occur on an N allele; these nucleotide changes are not given.Phenotype Allele name Nucleotide change Intron/ExonMNS:1 or M+MNS:2N+MNS:1,-2,8†M c +MNS:7,9,–40Vw+MNS:-1,-2,11M g +MNS:12Vr+MNS:14Mt(a+)MNS:16Ri(a+);GYPA*01Amino acid changeGYPA*M 59C; 71G; 72T 2 Ser20, Gly24GYPA*02GYPA*N 59C>T; 71G>A; 72T>G 2 Ser20Leu, Gly24GluGYPA*08GYP.Mc71G>A,72T>G 2Gly24GluGYPA*09GYPA*Vw 140C>T 3 Thr47MetGYPA*11GYPA*Mg68C>A 2 Thr23AsnGYPA*12GYPA*Vr 197C>A 3 Ser66TyrGYPA*14GYPA*Mta 230C>T 3 Thr77IleGYPA*16GYPA*Ria 226G>A 3 Glu76LysMNS:18Ny(a+) GYPA*18 138T>A 3 Gln46GluMNS:7,19,–40Hut+MNS:31Or+MNS:37ERIK+GYPA*19GYPA*Hut 140C>A 3 Thr47LysGYPA*31GYPA*Or 148C>T 3 Arg50TrpGYPA*37GYPA*ERIK 232G>A 4 Gly78ArgMNS:38 GYPA*38 217C>T 3 Pro73SerCommentsSee alsoGYP.EBH in hybrid tablePage 2 of 10
Names for MNS blood group alleles v2.0 110914Phenotype Allele name Nucleotide change Intron/ExonOs(a+)GYPA*OsaMNS:–39,41HAG+MNS:–42,43MARS+GYPA*41GYPA*HAG 250G>C 4 Ala84ProGYPA*43GYPA*MARS 244C>A 4 Glu82LysMNS:–45ENEV– GYPA*–45 242T>G 4 Val81GlyMNS:46MNTD+GYPA*46GYPA*MNTD 107C>G 3 Thr36ArgAmino acid changeComments† Most anti-M but only few anti-N react with M c + RBCsPage 3 of 10
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Names for MNS Blood Group Alleles

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