Names for MNS Blood Group Alleles

Names for MNS blood group alleles v2.0 110914Phenotype Allele name Nucleotide Protein CommentsMNS:10,32Mur +, Dane+MNS:10,32,–44Mur +, Dane+,ENDA–MNS:26, 27Hop+,Nob+MNS:–26,27Hop–,Nob+MNS:20, –34Hil+, MINY–GYP.Vw Numbers have not been assigned to theseGYP.Hutalleles in this series and they are included intable 1. It has been proposed that they areGYP.Mcderived from hybrid genes but the crossoverGYP.Mgpoints have not been determinedexperimentally.GYP*301.01GYP.DaneGYP*301.02GYP.DaneGYP*302.01GYP.JohGYP*302.02GYP.NobGYP*303GYP.KIGYP(A1-159–BΨ160-177–A178-450); 191T>AGYP(A1-159–BΨ160-177–A178-450)GYP(A1-202–BΨ203–A204-450)GYP(A1-202–BΨ203-212–A213-450)203G>C; 212A>CGYP(A1-238–B239-242–A243-450)239G>C; 242T>GGP(A1-52-B53-58-A59-149);Ile46AsnGP(A1-52-B53-58-A59-149)GPA(1-67)-B(68)-GPA(69-150)Arg68ThrGPA(1-67)-B(68-72)-GPA(73-150)Arg68Thr; Tyr71SerGPA(1-79)-B(80-81)-GPA(82-150)Arg80Thr;Val81GlyAlso expresses Mur antigenAlso expresses Mur antigen; does notexpress ENDAGene conversion in exon 3 replaces GYPAnucleotide 203 with the correspondingnucleotide from GYPBΨ3. This is theminimum but the breakpoint is not defined.Gene conversion in exon 3 replaces GYPAnucleotides (203-212) with correspondingnucleotides from GYPBΨ3. This is theminimum but the breakpoint is not defined.Gene conversion in exon 4 replaces GYPAnucleotides (239-242) with correspondingnucleotides from GYPB. This is the minimumbut the breakpoint is not defined.Page 7 of 10